Lipoprotein News and Research

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A lipoprotein is a biochemical assembly that contains both proteins and lipids. The lipids or their derivatives may be covalently or non-covalently bound to the proteins.

COVID-19 triggers metabolic signatures in kids that mirror adult heart risk

Children with acute COVID-19 and MIS-C show significant disruptions in lipid metabolism, including patterns resembling adult severe COVID-19. These findings highlight potential long-term cardiovascular risks in pediatric SARS-CoV-2 cases and underscore the need for follow-up care.

16 Jun 2025

New therapeutic approach targets PCSK9 to regulate blood cholesterol levels

When the amount of cholesterol in the blood is too high, hypercholesterolemia can develop, causing serious damage to the arteries and cardiovascular health.

11 Jun 2025

Heart drug repurposed to kill hospital superbug Acinetobacter baumannii

A new study from Emory University addresses the growing global crisis of antibiotic-resistant infections. Many of these drug-resistant bacteria are spread through hospitals, and there are few antibiotics available for treatment.

10 Jun 2025

Small weight loss leads to big gains in heart health

Even without weight loss, healthy lifestyle changes enhance heart health. This study highlights the importance of habits for cardiometabolic improvement.

9 Jun 2025

Study explores the connection between abnormal uterine bleeding and hyperinsulinemia

Insulin resistance is becoming more common because of a combination of lifestyle factors, genetics, and medical conditions. A lot of those same risk factors play a role in abnormal uterine bleeding.

4 Jun 2025

Phytosterols in plant-based foods linked to lower risk of heart disease and type 2 diabetes

Heart disease and type 2 diabetes rank among the leading causes of death and disability in the United States, and eating a healthy diet rich in plant-based foods can help to prevent or delay both of these conditions.

3 Jun 2025

Research uncovers new links between blood lipid profiles and risk of developing Alzheimer's

People who are at higher risk for heart disease also seem more likely to develop dementia.

30 May 2025

Choosing better carbs in low-carb diets boosts health outcomes

A long-term study of the Framingham Heart Study Offspring cohort found that low-carbohydrate diets emphasizing high-quality carbs, like whole grains, fruits, and vegetables, were linked to reduced inflammation and oxidative stress. Diets low in carbohydrate quality offered no such benefits.

29 May 2025

Coronary inflammation marker helps identify hidden heart risk in young adults

Researchers found that peri-coronary adipose tissue attenuation (PCAT), a marker of coronary inflammation, is independently associated with coronary artery disease (CAD) in young adults. Adding PCAT to standard risk models improved detection of early atherosclerosis, even in patients with a zero calcium score.

28 May 2025

Eating kombu daily enhances gut health and heart markers in men

A 12-week randomized trial found that daily intake of boiled kombu (Laminaria japonica) powder reduced body fat and raised adiponectin in Japanese men, while improving blood pressure and gut microbiota in both sexes. No significant effects were seen in women for body fat reduction or adiponectin.

20 May 2025

Portfolio diet delays heart risk and lowers cholesterol in young adults

A University of Toronto study found that higher adherence to the plant-based Portfolio Diet was associated with lower LDL cholesterol and improved cardiovascular risk markers in young adults. Modeling suggests the diet may delay cardiovascular risk onset by up to 13 years.

14 May 2025

Millions of women may be unaware of their risk for cardiovascular-kidney-metabolic disease

Millions of women may be unknowingly living with risk factors for heart, kidney and metabolic disease – interconnected conditions that together drive risk for cardiovascular disease, the leading cause of death among women, according to experts with the American Heart Association, a global force changing the future of health for all.

12 May 2025

Obicetrapib slashes LDL cholesterol by over 30% in high-risk heart patients

A large multinational trial published in the New England Journal of Medicine shows that obicetrapib significantly lowers LDL cholesterol in high-risk cardiovascular patients. The CETP inhibitor also improved key lipid parameters with no major safety concerns, supporting its role in future combination therapies.

8 May 2025

Low testosterone linked to higher kidney stone risk in men, study finds

A large cross-sectional study in South Korea found that men with low testosterone levels (below 3.33 ng/mL) were significantly more likely to have kidney stones. This association held even after adjusting for age and metabolic risk factors, suggesting testosterone may play a protective role.

6 May 2025

Can your diet affect fertility? Gut-linked dietary score reveals surprising risk pattern

A cross-sectional study of over 3,000 U.S. women found a non-linear link between a gut microbiota-based dietary index (DI-GM) and infertility. Risk decreased with healthier diets but unexpectedly rose beyond a certain threshold score.

4 May 2025

Researchers tie childhood vitamin D shortfalls to adult heart disease

Low childhood levels of 25-hydroxyvitamin D were linked to a significantly higher risk of early adult-onset atherosclerotic cardiovascular disease (ASCVD). The association remained even after accounting for conventional childhood risk factors and persisted across multiple analyses.

30 Apr 2025

Better sleep, BMI, and glucose control lower female infertility odds

A new study using NHANES data found that higher Life’s Crucial 9 (LC9) scores, reflecting better cardiovascular and mental health, were linked to lower odds of female infertility. However, adding depression to the LE8 framework did not significantly improve its predictive value.

29 Apr 2025

Disrupted body clocks raise risk of early death, study finds

A large cohort study from China and the U.S. shows that Circadian Syndrome (CircS)—a cluster of metabolic and behavioral disruptions—is linked to higher all-cause and cause-specific mortality. The risk increases with the number of CircS components, especially among adults aged 40–60.

29 Apr 2025