Pathology News and Research

RSS

Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Gene fusion patterns refine classification of rare acute leukemias

Acute leukemias with chimeric fusion genes involving FET (FUS, EWSR1, and TAF15) family proteins and ETS (E26 transformation-specific)-like transcription factors often present with unique clinical and pathological characteristics.

27 Jun 2026

Artificial intelligence improves diagnostic accuracy in clinical breast pathology

Artificial intelligence (AI) is increasingly reshaping diagnostic pathology, with breast pathology representing one of the most advanced and clinically impactful areas of adoption.

26 Jun 2026

New accessible multiplex imaging workflow advances spatial liver research

Spatial biology technologies are reshaping modern biomedical research by enabling the visualization of cellular organization and interactions within intact tissues.

26 Jun 2026

Iron overload gradually increases neurons' vulnerability to neurodegeneration

Neurodegenerative diseases affect tens of millions of people worldwide. Among these, Alzheimer's and Parkinson's diseases are the most common; in the United States alone, the Alzheimer's Disease Association and Parkinson's Foundation report roughly 7 million people with Alzheimer's and another million with Parkinson's.

25 Jun 2026

New diagnostic platform enables automated HER2 scoring of breast cancer tissue samples

Researchers at the University of California, Los Angeles have developed a compact, cost-effective diagnostic platform combining lensfree holography and deep learning for automated HER2 scoring of breast cancer tissue samples.

25 Jun 2026

Researchers uncover key mechanism driving chronic Sjögren disease

Sjögren disease, an autoimmune disease characterized by dry mouth and dry eyes, may reduce patients’ quality of life.

24 Jun 2026

New TRUECAM wrapper makes medical artificial intelligence more trustworthy

Medical artificial intelligence (AI) faces a fundamental challenge: uncertainty quantification. Artificial neural networks are largely unaware of the limits of their training data and can become overconfident when confronted with unfamiliar inputs. Suppose you train a neural network to distinguish among African mammals.

23 Jun 2026

New AI platform tracks cancer treatment responses in tumor organoids

Researchers at the UCLA Health Jonsson Comprehensive Cancer Center have developed a new platform that combines 3D bioprinting, advanced imaging and artificial intelligence to better monitor how cancer responds to treatment.

22 Jun 2026

Psychological traits may uncover why Alzheimer’s biology differs between patients

In 822 deceased older adults from ROS and MAP, researchers linked stable psychological traits to multi-omic molecular subtypes of Alzheimer’s dementia using postmortem brain tissue from the dorsolateral prefrontal cortex. Neuroticism and loneliness were associated with molecular progression, while purpose in life showed subtype-specific inverse associations, suggesting psychological traits may align with Alzheimer’s biology beyond conventional neuropathology.

22 Jun 2026

Researchers advocate local data strategies for early cancer detection

Researchers are calling for the application of locally driven strategies, supported by stronger regional evidence, to improve early cancer detection and precise care.

22 Jun 2026

Synthetic gut communities reveal how diet rewires the microbiome

Synthetic microbial communities give researchers controlled models for testing how diet reshapes gut microbial ecology, metabolism, and host-relevant responses. The review highlights how SynComs can strengthen causal inference, improve intervention testing, and support future precision nutrition, while noting major challenges in stability, standardization, and ecological realism.

21 Jun 2026

AI imaging technique detects early endometrial cancer with high accuracy

Endometrial cancer is the most common gynecologic cancer, with more than 69,000 cases diagnosed in the U.S. in 2025 and increasing up to 3% annually.

18 Jun 2026

Massage gun use around eyes may cause serious retinal injuries

Using a massage gun on or around the eyes risks major tearing and bruising to the retina-the light sensitive tissue at the back of the eye-doctors warn in the online journal BMJ Case Reports after treating a young man who had used one of these devices.

18 Jun 2026

New spatial map reveals treatment vulnerabilities in bladder cancer

Researchers at The University of Texas MD Anderson Cancer Center have developed a spatial map of muscle-invasive bladder cancer, revealing how tumor cell states, immune environments and therapeutic vulnerabilities are organized within tumors.

18 Jun 2026

Early life stress leaves unique biological signatures in cells

New research links childhood adversity to mitochondrial bioenergetic changes later in life, underscoring the impact of stress in early life on cellular health.

18 Jun 2026

Preoperative radiation boosts immunotherapy response in brain metastases

A new study led by researchers at The University of Texas MD Anderson Cancer Center demonstrated that pre-operative radiation therapy for brain metastases not only targets tumor cells directly but also can activate immune pathways that can make tumors more receptive to immunotherapy.

17 Jun 2026

WashU study identifies shared target for a new diarrhea vaccine

The bacteria enterotoxigenic E. coli and Shigella together cause hundreds of millions of infections each year and are among the leading causes of diarrheal death, especially in children.

17 Jun 2026

Key Alzheimer's protein actively protects neurons from nuclear damage

Researchers at Niigata University's Brain Research Institute have uncovered a new function of amyloid precursor protein (APP), a molecule long studied as the precursor to amyloid-β (Aβ) in Alzheimer's disease (AD).

17 Jun 2026

Houston Methodist study reveals how strep bacterium causes infection

A fast-rising strep bacterium has become increasingly notorious for causing serious infections in humans, including complications that can lead to muscle damage and patient death. New Houston Methodist research appearing in The American Journal of Pathology, published by Elsevier, sheds light on how Streptococcus dysgalactiae subspecies equisimilis (SDSE) causes disease and may provide important insights to aid in vaccine development.

17 Jun 2026

USC study reveals nuanced Alzheimer's genetic risk in Hispanic populations

Researchers at the USC Mark and Mary Stevens Neuroimaging and Informatics Institute (Stevens INI) at the Keck School of Medicine of USC analyzed brain imaging and clinical data from more than 17,000 participants across five major aging and Alzheimer's disease studies.

17 Jun 2026