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Study suggests concomitant antidepressant and statin use could prevent treatment discontinuation

A recent study in the journal BMC Medicine evaluates the real-world impact of combining antidepressants with statins in UK adults, revealing lower discontinuation rates but similar efficacy compared to antidepressant-only treatment.

12 Nov 2023

Obinutuzumab shows promise in preserving kidney function, preventing flares in lupus nephritis patients

In a post hoc analysis of the phase 2 NOBILITY trial, researchers found that treatment with obinutuzumab-;an antibody that targets a protein expressed on certain immune cells-;was superior to placebo for preserving kidney function and preventing flares in patients with lupus nephritis, a kidney condition associated with the autoimmune disease lupus.

10 Nov 2023

Mucosal vaccine shows lasting defense against SARS-CoV-2 Omicron in primate study

In this groundbreaking study, researchers developed a mucosal adenoviral-vector vaccine, ChAd-SARS-CoV-2-S, which demonstrated sustained and robust immunity against a challenging Omicron variant in nonhuman primates, indicating a promising direction for durable COVID-19 protection strategies. Unlike traditional intramuscular vaccines, this mucosal vaccine elicited a comprehensive immune response, potentially paving the way for more effective and long-lasting COVID-19 vaccines.

9 Nov 2023

Patients with advanced HER2-positive breast cancer live longer if treated with pyrotinib, trial shows

Patients with HER2-positive breast cancer that has started to spread to other parts of the body survive for longer if they are treated with a new drug called pyrotinib, according to results from the longest follow-up of the PHOEBE randomized clinical trial in China.

8 Nov 2023

Which pharmacotherapies are associated with improved outcomes for people with alcohol use disorder?

Researchers assessed the efficacy and compared the relative effectiveness of various pharmacological treatments for alcohol use disorder.

8 Nov 2023

The effect of vegetarian diets on sports performance

The effects of vegetarian and omnivorous diets on athletic performance.

8 Nov 2023

Three new studies show low-dose atropine can help slow myopia in children

Myopia, or nearsightedness, is at an all-time high among children in the US. Globally, half the population is expected to be nearsighted by 2050.

6 Nov 2023

Study probes the hidden impact of low-cal sweeteners on gut health

The research scrutinizes the impact of low- and non-calorie sweeteners on gut microbiota, suggesting potential links to glucose tolerance and insulin resistance, with varying results across studies indicating a need for more comprehensive research.

5 Nov 2023

SSRIs show promise in easing post-COVID struggles, Dutch study reveals

Dutch study finds SSRIs significantly alleviate post-COVID syndrome symptoms, offering promising treatment avenues and shedding light on neurobiological mechanisms at play.

5 Nov 2023

How caffeine impacts cerebral blood flow

Caffeine consumption affects cerebral blood flow in young adults, with the study showing a dose-dependent reduction in arterial velocity post-intake. This impact on the cardiovascular system suggests caffeine's vasodilatory effects on cerebral arteries.

5 Nov 2023

Sotagliflozin provides kidney and heart benefits in patients with diabetes and chronic kidney disease

Sodium-glucose cotransporter-2 (SGLT2) inhibitors, which are medications that lower blood sugar levels among other effects, provide kidney- and heart-related benefits to patients with and without diabetes.

3 Nov 2023

High-impact clinical trial results to be presented at ASN Kidney Week 2023

The results of numerous high-impact clinical trials that could affect kidney-related medical care will be presented in-person at ASN Kidney Week 2023 November 1–November 5.

3 Nov 2023

Study launched to test a vaginal film that slowly dissolves over the course of 30 days

A vaginal film designed to slowly dissolve over the course of 30 days is being put to the test for the first time in a study launched this week that aims to determine its feasibility and acceptability as a potential HIV prevention method for women.

2 Nov 2023

New treatment breakthrough: Pyrotinib combo demonstrates remarkable efficacy for HER2 positive metastatic breast cancer

The safety and efficacy of treating human epidermal growth factor receptor 2 (HER2)-positive metastatic breast cancer with pyrotinib.

2 Nov 2023

Daily strawberry consumption could help reduce dementia risk for middle-aged individuals

New research from the University of Cincinnati found that daily strawberry consumption could help reduce the risk of dementia for certain middle-aged populations.

1 Nov 2023

Sweet truths: Could blackcurrant and citrus extracts help prevent type 2 diabetes?

In a recent study, European researchers found that blackcurrant (BC) extracts can lower blood sugar levels immediately after meals, but higher doses aren't more effective and fruit fibers don't boost the effect. Despite limitations, the study offers new directions for researching dietary interventions in managing type 2 diabetes and blood glucose levels.

1 Nov 2023

Spicing up memory: Wasabi found to boost brainpower in seniors

A 12-week study on adults over 60 found that wasabi supplements containing 6-MSITC significantly improved episodic and working memory. While other cognitive domains showed no improvement, the findings suggest that wasabi's anti-inflammatory and anti-oxidant properties may offer new avenues for combating age-related memory decline.

31 Oct 2023

New drug gets FDA approval for the treatment of common genetic disease in young boys

A new drug developed by professors from the School of Pharmacy and Pharmaceutical Sciences at Binghamton University has received Food and Drug Administration (FDA) approval for the treatment of patients with Duchenne muscular dystrophy (DMD), a common genetic disease that mostly affects young boys.

31 Oct 2023

Updated toolkit to guide global menopause care

Care for women with menopausal health issues should improve globally following the release of an updated Monash University-led toolkit that guides health professionals around the world in assessing and treating them.

30 Oct 2023

New drug candidate found to be highly effective in treating rare sight-threatening eye infection

A drug candidate, based on pioneering UCL and Moorfields Eye Hospital research and currently under development by SIFI S.p.A., has been found to be highly effective in treating a rare sight-threatening eye infection in a new international clinical trial.

26 Oct 2023

Placebo News and Research

Study suggests concomitant antidepressant and statin use could prevent treatment discontinuation

Obinutuzumab shows promise in preserving kidney function, preventing flares in lupus nephritis patients

Mucosal vaccine shows lasting defense against SARS-CoV-2 Omicron in primate study

Patients with advanced HER2-positive breast cancer live longer if treated with pyrotinib, trial shows

Which pharmacotherapies are associated with improved outcomes for people with alcohol use disorder?

The effect of vegetarian diets on sports performance

Three new studies show low-dose atropine can help slow myopia in children

Study probes the hidden impact of low-cal sweeteners on gut health

SSRIs show promise in easing post-COVID struggles, Dutch study reveals

How caffeine impacts cerebral blood flow

Sotagliflozin provides kidney and heart benefits in patients with diabetes and chronic kidney disease

High-impact clinical trial results to be presented at ASN Kidney Week 2023

Study launched to test a vaginal film that slowly dissolves over the course of 30 days

New treatment breakthrough: Pyrotinib combo demonstrates remarkable efficacy for HER2 positive metastatic breast cancer

Daily strawberry consumption could help reduce dementia risk for middle-aged individuals

Sweet truths: Could blackcurrant and citrus extracts help prevent type 2 diabetes?

Spicing up memory: Wasabi found to boost brainpower in seniors

New drug gets FDA approval for the treatment of common genetic disease in young boys

Updated toolkit to guide global menopause care

New drug candidate found to be highly effective in treating rare sight-threatening eye infection

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