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Runx1 overexpression triggers early intervertebral disc degeneration

A new research paper was published in Volume 17, Issue 9 of Aging-US on September 8, 2025, titled, "Runx1 overexpression induces early onset of intervertebral disc degeneration."

17 Oct 2025

Targeting the glycocalyx may offer a new approach to reduce frailty in older adults

A new research paper was published in Volume 17, Issue 9 of Aging-US on August 30, 2025, titled, "Glycocalyx-targeted therapy prevents age-related muscle loss and declines in maximal exercise capacity."

14 Oct 2025

Gaps in sex education can have lasting impacts throughout adulthood, study finds

A new Kinsey Institute study has found gaps in sex education can have lasting impacts throughout adulthood, including relationship struggles, lack of confidence, and reduced quality of life.

10 Oct 2025

Lifestyle choices and hormonal imbalances can impact men's reproductive health

A new research paper was published in Volume 12 of Oncoscience on September 30, 2025, titled "Lifestyle and hormonal factors affecting semen quality and sperm DNA integrity: A cross-sectional study."

10 Oct 2025

New insights into malaria proteins offer pathway to blocking parasite transmission

Using millions of microscope images magnified up to 130,000 times, researchers from Radboud university medical center and Toronto have unraveled the structure of two key proteins in the malaria parasite.

10 Oct 2025

Socially enriched environments linked to better memory and cognitive flexibility in aged rats

A new research paper was published in Volume 17, Issue 9 of Aging-US on August 22, 2025, titled, "The impact of long-term social housing on biconditional association task performance and neuron ensembles in the anterior cingulate cortex and the hippocampal CA3 region of aged rats."

9 Oct 2025

Engineered Salmonella therapy delivers immune payloads to combat cancer

A new research paper was published in Volume 16 of Oncotarget on October 6, 2025, titled "ACTM-838, a novel systemically delivered bacterial immunotherapy that enriches in solid tumors and delivers IL-15/IL-15Rα and STING payloads to engage innate and adaptive immunity in the TME and enable a durable anti-tumor immune response."

8 Oct 2025

Deregulated miR-145 and miR-27b impact adipogenesis in Hutchinson-Gilford progeria syndrome

A new research paper was published in Volume 17, Issue 9 of Aging-US on August 27, 2025, titled, "Deregulated miR-145 and miR-27b in Hutchinson-Gilford progeria syndrome: implications for adipogenesis."

7 Oct 2025

Why do females live longer in mammals but males in birds?

A global study reveals sexual selection influences life expectancy differences between sexes in mammals and birds, reshaping aging research and public health.

7 Oct 2025

Reproductive health agencies call for a major shift in diagnosis and treatment of postpartum hemorrhage

Through landmark new guidelines released today, leading reproductive health agencies are calling for a major shift in how postpartum hemorrhage (PPH) is prevented, diagnosed and treated.

6 Oct 2025

Why women’s periods once synced with the moon — and what changed

Study reveals women's menstrual cycles follow lunar gravity, with synchronization detected during strong seasonal alignments despite artificial light effects.

30 Sep 2025

Does the menstrual cycle change sports performance?

This review analyzes nearly three decades of research on menstrual cycle phases and their inconsistent effects on women's athletic performance and physiology.

26 Sep 2025

Colorectal cancer first presents with unexplained strokes and blood clots

A new case report was published in Volume 12 of Oncoscience on September 15, 2025, titled "When strokes reveal a hidden malignancy: An atypical case of metastatic colorectal cancer with extensive thromboembolism."

25 Sep 2025

Researchers uncover how chromosome crossovers protect fertility

When a woman becomes pregnant, the outcome of that pregnancy depends on many things - including a crucial event that happened while she was still growing inside her own mother's womb.

24 Sep 2025

Loss of Trp53 gene affects immune responses in ovarian cancer

A new research paper was published in Volume 16 of Oncotarget on September 22, 2025, titled "Loss of Trp53 results in a hypoactive T cell phenotype accompanied by reduced pro-inflammatory signaling in a syngeneic orthotopic mouse model of ovarian high-grade serous carcinoma."

24 Sep 2025

Study reveals how a key spinal circuit shapes the choreography of sex

For decades, it was thought that while the brain orchestrated male sexual behaviour – arousal, courtship, and copulation – the spinal cord merely executed the final act: ejaculation.

23 Sep 2025

Senescent cell subtypes do not respond equally to treatment, study shows

A new research paper was published in Volume 17, Issue 8 of Aging-US on August 7, 2025, titled "Senescent cell heterogeneity and responses to senolytic treatment are related to cell cycle status during senescence induction."

23 Sep 2025

Muscle hormone FGF21 linked to longer survival in ALS

A new research paper was published in Volume 17, Issue 8 of Aging-US on August 9, 2025, titled "The myokine FGF21 associates with enhanced survival in ALS and mitigates stress-induced cytotoxicity."

18 Sep 2025

Loss of key Y chromosome gene causes infertility in male mice

In a new study conducted at the University of Hawaiʻi at Mānoa, researchers from the John A. Burns School of Medicine (JABSOM) have shown that the loss of a key male fertility gene leads to infertility and changes expression of hundreds of other important genes.

17 Sep 2025

Common bladder infection may signal urogenital cancer risk

A bout of the common bladder infection, cystitis, may signal the presence of urogenital cancers-which affect parts of the body involved in reproduction and excretion-in middle aged adults, suggests research published in the open access journal BMJ Public Health.

17 Sep 2025