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Dartmouth TB vaccine moves one step closer to a full Phase 3 efficacy trial

Results from the Phase 2 trial of the DAR-901 tuberculosis (TB) vaccine were announced today by investigators at Dartmouth's Geisel School of Medicine and published in the journal Vaccine.

29 Sep 2020

WHO offers guideline on managing pharmaceutical prices

Unaffordable prices can be one of the biggest barriers to access to pharmaceutical products. A new WHO guideline for countries on managing pharmaceutical prices aims to help governments overcome this barrier and better address national public health needs.

29 Sep 2020

COVID-19-related interruptions in rehabilitation care causes emotional distress in breast cancer survivors

Beyond the tragic surges in hospitalizations and deaths, the first months of the COVID-19 pandemic disrupted healthcare for people with a wide range of medical conditions - including cancer.

29 Sep 2020

New agreements to ensure all countries have fair access to COVID-19 rapid diagnostic tests

A set of agreements to make available, for low and middle-income countries, affordable, high-quality COVID-19 antigen rapid tests were today announced by the Access to COVID-19 Tools (ACT) Accelerator.

28 Sep 2020

J&J's COVID-19 vaccine shows potent immune response in phase 2 human trial

A multicenter phase 1/2a randomized, double-blinded, placebo-controlled clinical trial has been conducted recently to evaluate the safety, reactogenicity, and immunogenicity of a non-replicating adenovirus-based vaccine, namely Ad26.COV2.S against severe acute respiratory coronavirus 2 (SARS-CoV-2) infection.

28 Sep 2020

Resveratrol and pterostilbene inhibit SARS-CoV-2 infection in vitro

A team of scientists at the University of Groningen, in the Netherlands, demonstrates that a natural plant product, resveratrol, and its structural analog, pterostilbene, have long-lasting antiviral effects against severe acute respiratory coronavirus 2 (SARS-CoV-2) infection. The study is currently available on the bioRxiv preprint server.

28 Sep 2020

Clover Biopharma's new trimeric subunit vaccine candidate prevents COVID-19 in monkeys

The vaccine candidate produced a high level of neutralizing antibodies in animal models. Rhesus macaques immunized with the vaccine candidate showed reduced viral loads in the lungs. The research is published on the preprint server bioRxiv.

28 Sep 2020

New study highlights success of health program's clinical van and street outreach

A novel mobile health program created in early 2018 by the Kraft Center for Community Health at Massachusetts General Hospital (MGH) has proven to be an effective model for bringing opioid addiction treatment services directly to marginalized individuals, particularly the homeless, a population that faces the highest risk of near-term death from drug overdose.

26 Sep 2020

Conflict, climate instability, and COVID-19 are affecting the health of women and children

Fragile gains made to advance women and children's health are threatened by conflict, the climate crisis and COVID-19, according to a new report from Every Woman Every Child.

25 Sep 2020

Experimental cancer drug AR-12 inhibits SARS-CoV-2 virus

Nine months into the global pandemic, which has infected more than 32 million people, there is still no approved effective and safe drug or vaccine against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

24 Sep 2020

Federal restrictions on corneal donations prevent vision-restoring surgery

Some forms of blindness and visual impairment can be cured with a corneal transplant surgery using donated eye tissue. However, federal regulations in the United States and Canada severely restrict the ability of sexually active gay and bisexual men from donating their eye tissue.

24 Sep 2020

These secret safety panels will pick the COVID vaccine winners

Most Americans have never heard of Dr. Richard Whitley, an expert in pediatric infectious diseases at the University of Alabama-Birmingham.

24 Sep 2020

AI used to define the cytokine storm implicated in fatal COVID-19

A new study published on the preprint server bioRxiv* in September 2020 reports the use of artificial intelligence (AI) to identify an invariant or universal host immune response found in all viral pandemics so far. The association of this response with severe COVID-19 phenotypes indicates a new understanding of the human immune response in viral pandemics.

24 Sep 2020

Fourth Phase 3 clinical trial evaluating COVID-19 vaccine begins in the U.S.

A fourth Phase 3 clinical trial evaluating an investigational vaccine for coronavirus disease 2019 (COVID-19) has begun enrolling adult volunteers.

23 Sep 2020

New T-cell-based vaccine strategy provides broader protection against seasonal influenza

As Americans begin pulling up their sleeves for an annual flu vaccine, researchers at the University of Wisconsin-Madison have provided new insights into an alternative vaccine approach that provides broader protection against seasonal influenza.

23 Sep 2020

Drugs used to treat HIV and hepatitis B could be repurposed to prevent type 2 diabetes

A group of drugs used to treat HIV and hepatitis B could be repurposed to prevent type 2 diabetes, a new study suggests.

23 Sep 2020

HIV drugs cause immune-system changes that can improve resistance to viral infections

Drugs currently used to keep the HIV virus in check also cause immune-system changes that might make humans better able to resist viral infections – but might also cause harmful inflammation, according to a study published today in Cell Reports Medicine.

23 Sep 2020

HIV News and Research

Dartmouth TB vaccine moves one step closer to a full Phase 3 efficacy trial

WHO offers guideline on managing pharmaceutical prices

COVID-19-related interruptions in rehabilitation care causes emotional distress in breast cancer survivors

New agreements to ensure all countries have fair access to COVID-19 rapid diagnostic tests

J&J's COVID-19 vaccine shows potent immune response in phase 2 human trial

Resveratrol and pterostilbene inhibit SARS-CoV-2 infection in vitro

Clover Biopharma's new trimeric subunit vaccine candidate prevents COVID-19 in monkeys

New study highlights success of health program's clinical van and street outreach

Conflict, climate instability, and COVID-19 are affecting the health of women and children

Experimental cancer drug AR-12 inhibits SARS-CoV-2 virus

Federal restrictions on corneal donations prevent vision-restoring surgery

These secret safety panels will pick the COVID vaccine winners

AI used to define the cytokine storm implicated in fatal COVID-19

Fourth Phase 3 clinical trial evaluating COVID-19 vaccine begins in the U.S.

New T-cell-based vaccine strategy provides broader protection against seasonal influenza

Drugs used to treat HIV and hepatitis B could be repurposed to prevent type 2 diabetes

HIV drugs cause immune-system changes that can improve resistance to viral infections

A subunit SARS-CoV-2 vaccine may offer broader protection against virus

Hospitalized COVID-19 patients may face increased risk for kidney injury

Study explores women's interest in long-acting injectable PrEP to prevent HIV

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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