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Parkinson's disease diagnosed after SARS-CoV-2

As the COVID-19 pandemic continues to spread, new and unusual chronic sequelae of the disease are cropping up in many medical practices. Now, a new case paper published in The Lancet in September 2020 describes a case of new-onset Parkinson's disease following infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

22 Sep 2020

Research consortium receives $111 million NCI grant to prevent, treat HIV-related cancers

The widespread use of antiretroviral therapy to suppress the HIV virus has helped tens of millions of people with HIV live healthier, longer lives--but an unfortunate consequence of people living longer with HIV is an increased risk of cancer.

22 Sep 2020

Soluble ACE2 microbody blocks SARS-CoV-2 entry into lung cells

A new study by researchers at NYU Langone Medical Center and Weill Cornell Medical College and published on the preprint server bioRxiv* in September 2020 reports the potential of an angiotensin-converting enzyme 2 (ACE2)-antibody Fc complex in a new format that seems to offer more significant inhibition of SARS-CoV-2.

21 Sep 2020

In vitro testing suggests effective novel drug combinations for SARS-CoV-2

A recent study published on the preprint server bioRxiv* in September 2020 shows the value of drug combinations to enhance the therapeutic and preventive efficacy of such repositioned drugs in standard antiviral therapy.

20 Sep 2020

Lopinavir-ritonavir does not suppress SARS-CoV-2 activity in vitro

Among them is the combination of lopinavir and ritonavir, which have been in use in an attempt to reduce the severity of the disease. However, a new South Korean study published on the preprint server bioRxiv in September 2020 shows that this combination is ineffective against the virus.

20 Sep 2020

UConn researchers validate clinical feasibility of CRISPR-based platform for COVID-19 testing

In March, researchers in the Department of Biomedical Engineering-- a shared department in the schools of Dental Medicine, Medicine, and Engineering--began to develop a new, low-cost, CRISPR-based diagnostic platform to detect infectious diseases, including HIV virus, the novel coronavirus (SARS-CoV-2).

19 Sep 2020

Combination of two mosquito-borne viruses may be a trigger for stroke

A deadly combination of two mosquito-borne viruses may be a trigger for stroke, new research published in the The Lancet Neurology has found.

18 Sep 2020

S-pseudotyped VLPs offer promising COVID-19 vaccine platform

A new study published on the preprint server bioRxiv* in September 2020 reports on a Moloney murine leukemia virus (MLV) platform that produces VLPs expressing the important spike antigen of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

18 Sep 2020

Structural and systemic racism in health care system affects HIV care for black women

For Black women in the southern United States, mistrust of the health care system that is grounded in structural and systemic racism is a key factor affecting participation in HIV prevention and treatment services, reports a study in the September/October issue of The Journal of the Association of Nurses in AIDS Care (JANAC). The official journal of the Association of Nurses in AIDS Care, JANAC is published in the Lippincott portfolio by Wolters Kluwer.

18 Sep 2020

Researchers identify cause for thrombosis in COVID-19 patients

A new University of Kentucky College of Medicine study may provide answers for why so many COVID-19 patients experience thrombosis, or the formation of blood clots that obstruct blood flow through the circulatory system.

17 Sep 2020

New method quickly shows how antibiotics combine to stop bacterial growth

Researchers at Uppsala University have developed a new method to determine - rapidly, easily and cheaply - how effective two antibiotics combined can be in stopping bacterial growth.

17 Sep 2020

PrEP prescribing is not routine for many medical practitioners, study finds

Only about 54% of medical practitioners surveyed say they have prescribed pre-exposure prophylaxis, or PrEP, to HIV-vulnerable patients, according to a new study by a Vanderbilt University Medical Center investigator.

17 Sep 2020

Optimal antibody combinations and Fc binding inhibit SARS-CoV-2 in vivo

A recent study by researchers at the University of North Carolina at Chapel Hill and The Rockefeller University and published on the preprint server bioRxiv in September 2020 shows that a combination of neutralizing antibodies with intact Fc effector function can effectively reduce the viral load and prevent infection.

17 Sep 2020

Researchers compare developed carriers for delivery of genome editing tools with existing analogs

Researchers from Peter the Great St.Petersburg Polytechnic University in collaboration with colleagues from the Pavlov University, ITMO University, and the University of Hamburg compared their developed carriers for delivery of genome editing (GE) tools with other available analogs.

16 Sep 2020

Sub-Saharan Africa needs greater access to live-saving antibodies

Sub-Saharan Africa must increase access to live-saving, laboratory-produced antibodies, writes Yolanda Moyo.

16 Sep 2020

COVID vaccine trials move at warp speed, but recruiting Black volunteers takes time

Participation in clinical trials among Black people is low, according to Food and Drug Administration statistics.

16 Sep 2020

Pfizer's anti-viral 3CL protease inhibitor shows antiviral potential against SARS-CoV-2

Now, a new study by researchers from Pfizer, University of Arizona, Purdue University, The Scripps Research Institute, and UC San Diego School of Medicine and published on the preprint server bioRxiv in September 2020 reports that an enzyme inhibitor may act in synergism with the approved antiviral remdesivir to suppress viral replication in COVID-19.

16 Sep 2020

UTEP's MARC receives federal grant to fight opioid abuse in West Texas rural counties

The University of Texas at El Paso's Minority AIDS Research Center (MARC) is the subrecipient of a $1 million implementation grant to target substance use disorders and opioid use disorders in five rural counties along the Texas-Mexico border.

16 Sep 2020

New clinical trial shows combination of two innovative precision medicines could treat multiple cancers

Launching a dual-pronged attack on tumours using a combination of two innovative precision medicines could treat patients with multiple common cancers, a new clinical trial shows.

15 Sep 2020

Biologic therapy for psoriasis could lead to significant reduction in heart disease

Patients with psoriasis treated with biologic therapy, which are protein-based infusions to suppress inflammation, had a significant reduction in high-risk plaque in heart arteries, over one-year, according to new research published today in Circulation: Cardiovascular Imaging, an American Heart Association journal.

15 Sep 2020

HIV News and Research

Parkinson's disease diagnosed after SARS-CoV-2

Research consortium receives $111 million NCI grant to prevent, treat HIV-related cancers

Soluble ACE2 microbody blocks SARS-CoV-2 entry into lung cells

In vitro testing suggests effective novel drug combinations for SARS-CoV-2

Lopinavir-ritonavir does not suppress SARS-CoV-2 activity in vitro

UConn researchers validate clinical feasibility of CRISPR-based platform for COVID-19 testing

Combination of two mosquito-borne viruses may be a trigger for stroke

S-pseudotyped VLPs offer promising COVID-19 vaccine platform

Structural and systemic racism in health care system affects HIV care for black women

Researchers identify cause for thrombosis in COVID-19 patients

New method quickly shows how antibiotics combine to stop bacterial growth

PrEP prescribing is not routine for many medical practitioners, study finds

Optimal antibody combinations and Fc binding inhibit SARS-CoV-2 in vivo

Researchers compare developed carriers for delivery of genome editing tools with existing analogs

Sub-Saharan Africa needs greater access to live-saving antibodies

COVID vaccine trials move at warp speed, but recruiting Black volunteers takes time

Pfizer's anti-viral 3CL protease inhibitor shows antiviral potential against SARS-CoV-2

UTEP's MARC receives federal grant to fight opioid abuse in West Texas rural counties

New clinical trial shows combination of two innovative precision medicines could treat multiple cancers

Biologic therapy for psoriasis could lead to significant reduction in heart disease

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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