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Tandem myeloablative ASCT consolidation boosts neuroblastoma outcomes

Research presented at the American Society of Clinical Oncology annual conference suggests that consolidation therapy with tandem compared with single myeloablative autologous stem cell transplant can improve outcomes in paediatric patients with high-risk neuroblastoma.

12 Jun 2016

Immunoablation strengthens haemopoietic stem-cell transplantation effects in MS

Intensifying current transplant conditioning to remove rather than suppress immune cells ahead of autologous haematopoietic stem cell transplantation may result in long-term remission of multiple sclerosis, phase II trial findings show.

10 Jun 2016

About 30% of iPSCs not safe for clinical use, report multi-institutional researchers

As the promise of using regenerative stem cell therapies draws closer, a consortium of biomedical scientists reports about 30 percent of induced pluripotent stem cells they analyzed from 10 research institutions were genetically unstable and not safe for clinical use.

10 Jun 2016

MRI-guided focal laser ablation could be feasible, safe in prostate cancer patients

Prostate cancer patients may soon have a new option to treat their disease: laser heat. UCLA researchers have found that focal laser ablation - the precise application of heat via laser to a tumor - is both feasible and safe in men with intermediate risk prostate cancer.

10 Jun 2016

New method helps speed up bacterial identification

Pinpointing the type of bacteria that are at the root of an infection in clinical samples removed from living tissues, such as blood, urine or joint fluids, to quickly identify the best anti-microbial therapy still poses a formidable challenge.

10 Jun 2016

Carfilzomib therapy shows promise for pre-kidney transplant patients

Early findings by researchers at the University of Cincinnati College of Medicine suggest that the use of a second generation cancer drug, carfilzomib, may provide an improved approach for the reduction of antibodies in potential kidney transplant candidates.

10 Jun 2016

RNA editing enzyme ADAR1 may play role in regeneration of leukemia stem cells

Cancer stem cells are like zombies — even after a tumor is destroyed, they can keep coming back. These cells have an unlimited capacity to regenerate themselves, making more cancer stem cells and more tumors.

10 Jun 2016

First limbal stem cell transplant performed in Ireland

On Tuesday 7th June 2016, the first Limbal Stem Cell transplant in Ireland was performed by Mr. William Power, Consultant Ophthalmologist at the Royal Victoria Eye and Ear Hospital in Dublin.

10 Jun 2016

New study finds underutilization of PR therapy among older COPD patients

A new study from The University of Texas Medical Branch at Galveston investigating trends on the use of pulmonary rehabilitation therapy among older adults with chronic obstructive pulmonary disease found that this therapy was underutilized, despite its health benefits and cost effectiveness.

10 Jun 2016

Intrinsic subtyping of breast cancer can aid prognosis, treatment of tumor patients

Published in JAMA Oncology, Principal Investigator of Vall d´Hebron Institute of Oncology´s Translational Genomics Group, Team Leader of translational genomics and targeted therapeutics in solid tumors at the August Pi I Sunyer Biomedical Research Institute, and Head of Medical Oncology at the Hospital Clínic in Barcelona, Aleix Prat has led a study showing the intrinsic subtyping of breast cancer by means of a genomic test as the most important prognostic factor in advanced or metastatic hormone-sensitive breast cancer.

10 Jun 2016

Study shows rheumatologists underestimate disease severity in OA patients

The results of a study presented today at the European League Against Rheumatism Annual Congress showed patients with osteoarthritis (OA) are more likely to have the impact of their condition underestimated by rheumatologists than patients with Rheumatoid Arthritis (RA).

10 Jun 2016

Tackling Healthcare Challenges in a Changing World: an Interview with Professor Jeremy Nicholson

As individuals and as populations our risks of getting diseases are determined partly genetically and partly from the environment that we live in. An important part of that environment that mediates between the outside world and the inside world of our bodies is the microbiome.

10 Jun 2016

New drug ixekizumab helps clear severe psoriasis symptoms

About 80 percent of patients with moderate to severe psoriasis saw their disease completely or almost completely cleared with a new drug called ixekizumab, according to three large, long-term clinical trials led by Northwestern Medicine.

10 Jun 2016

BNPs have potential to enable early diagnosis, long-term treatment of RA with minimal side effects

The results of a study presented today at the European League Against Rheumatism Annual Congress showed that tiny particles made of a biodegradable polymer (BNPs -- biodegradable polymer nanoparticles) have the potential to enable early detection and efficient long-term treatment of rheumatoid arthritis (RA), with minimal side effects.

10 Jun 2016

Antibody-positive patients treated with infliximab less likely to benefit from infliximab biosimilar

The results of a study presented today at the European League Against Rheumatism Annual Congress showed that when antibodies develop in response to the biological treatment Remicade (infliximab), they also cross-react with the biosimilar of infliximab (CT-P13: Inflectra or Remsima).

10 Jun 2016

Scientists discover new ZBTB7A gene mutation that promotes growth of cancer cells

Biomarkers play an important role in modern cancer medicine. They are used as tools to diagnose cancers more precisely and to better predict the course of the disease.

10 Jun 2016

New IVF-based technique can reduce risk of mothers passing on mitochondrial disease to infants

A new IVF-based technique is likely to lead to normal pregnancies and reduce the risk that babies born will have mitochondrial disease, according to researchers at the Wellcome Trust Centre for Mitochondrial Disease at Newcastle University.

9 Jun 2016

Whole-exome sequencing can help characterize genetic alterations for commonly used bladder cancer cell lines

Much of basic cancer research is based on studies with cultured cancer cells. However, the usefulness of these studies greatly depends on how accurately these cancer cells grown in a dish represent human tumors.

9 Jun 2016

UAB receives new image-guided robotic system for early prostate cancer diagnosis

The world-renowned iSR'obotTM Mona Lisa makes its way to the United States, providing urologic surgeons with a tool to diagnose prostate cancer earlier through accurate diagnosis and precise localization that may allow for targeted treatments in the future.

9 Jun 2016

NMR-based metabolomics: an interview with Prof. Claudio Luchinat

Professor Claudio Luchinat, University of Florence and co-founder of the Magnetic Resonance Center (CERM), speaks to News-Medical about his research in NMR-based metabolomics.

From Bruker BioSpin Division 9 Jun 2016

Therapy News and Research

Tandem myeloablative ASCT consolidation boosts neuroblastoma outcomes

Immunoablation strengthens haemopoietic stem-cell transplantation effects in MS

About 30% of iPSCs not safe for clinical use, report multi-institutional researchers

MRI-guided focal laser ablation could be feasible, safe in prostate cancer patients

New method helps speed up bacterial identification

Carfilzomib therapy shows promise for pre-kidney transplant patients

RNA editing enzyme ADAR1 may play role in regeneration of leukemia stem cells

First limbal stem cell transplant performed in Ireland

New study finds underutilization of PR therapy among older COPD patients

Intrinsic subtyping of breast cancer can aid prognosis, treatment of tumor patients

Study shows rheumatologists underestimate disease severity in OA patients

Tackling Healthcare Challenges in a Changing World: an Interview with Professor Jeremy Nicholson

New drug ixekizumab helps clear severe psoriasis symptoms

BNPs have potential to enable early diagnosis, long-term treatment of RA with minimal side effects

Antibody-positive patients treated with infliximab less likely to benefit from infliximab biosimilar

Scientists discover new ZBTB7A gene mutation that promotes growth of cancer cells

New IVF-based technique can reduce risk of mothers passing on mitochondrial disease to infants

Whole-exome sequencing can help characterize genetic alterations for commonly used bladder cancer cell lines

UAB receives new image-guided robotic system for early prostate cancer diagnosis

NMR-based metabolomics: an interview with Prof. Claudio Luchinat

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

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