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Researchers use natural pigment for screening cell viability

Synthetic dyes are commonly used to assess the toxicity of chemical compounds in cell cultures. However, these dyes damage cells, rendering the cultures useless for long-term experiments.

25 Sep 2020

Automated computational protocol identifies potential SARS-CoV-2 MPro inhibitor

As scientists race to discover new and effective antiviral drugs against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), many novel approaches are being utilized. Now, a new study published on the preprint bioRxiv in September 2020 reports on the discovery of a potentially beneficial enzyme blocker that could inhibit SARS-CoV-2 viral replication.

24 Sep 2020

Polyphenolic compound offers new therapeutic option for chronic inflammatory disorders

Various plants and their products are known to contain "bioactive" ingredients that can alleviate human diseases. These "phytocompounds" often contain restorative biological properties such as anti-cancerous, antioxidant, and anti-inflammatory effects.

24 Sep 2020

Gruthan Bioscience to develop new class of cholesterol-lowering drugs

Gruthan Bioscience, LLC, a Medical University of South Carolina startup based in Charleston, South Carolina, received a Small Business technology Transfer (STTR) award from the National Heart, Blood and Lung Institute in August to take the next step in developing a novel class of cholesterol-lowering drugs to treat familial hypercholesterolemia.

24 Sep 2020

Chaperone-mediated autophagy could be a new therapeutic target for spinocerebellar ataxia

A research team from Kumamoto University, Japan has developed an animal model that reproduces motor dysfunction and cerebellar neurodegeneration similar to that in spinocerebellar ataxia (SCA) by inhibiting chaperone-mediated autophagy (CMA) in cerebellar neurons.

23 Sep 2020

SGD Pharma introduces Ensiemo, the new complete child-resistant packaging solution for CBD oils

SGD Pharma today announces the launch of its new full packaging solution dedicated to the cannabidiol (CBD) oil market.

From SGD Pharma 23 Sep 2020

Owlstone Medical releases positive study results on use of breath biopsy for better liver disease diagnosis

Owlstone Medical, the global leader in Breath Biopsy for applications in early disease detection and precision medicine, today announced the results of a patient study that successfully demonstrates the use of exhaled limonene as a breath biomarker to measure liver function and stage liver disease.

From Owlstone Medical Ltd 23 Sep 2020

Phase 2 clinical trial to examine the effects of razuprotafib on COVID-19 patients

Researchers at the University of Cincinnati and UC Health will host a Phase 2 clinical trial (NCT04511650) to examine the effects of a drug that targets blood vessel inflammation and injury in patients with COVID-19.

22 Sep 2020

Researchers identify a potential drug candidate for hand, foot and mouth disease

A study appearing next week in the journal Nature Communications offers some good news in the search for antiviral drugs for hard-to-treat diseases. Researchers have identified a potential new drug candidate against enterovirus 71, a common cause of hand, foot and mouth disease in infants and young children

22 Sep 2020

Genomic adaptations to rice‐based diets contribute to mitigation of metabolic risk

The traditional rice-based diet of some east-Asian population has brought to a number of genomic adaptations that may contribute to mitigating the spread of diabetes and obesity.

21 Sep 2020

Researchers identify a compound that inhibits growth of schwannomas

Schwannomas are tumors of the peripheral nervous system, which often occur in the genetic disease neurofibromatosis type 2. The research group of Prof. Dr. Helen Morrison at the Leibniz Institute on Aging - Fritz Lipmann Institute in Jena, Germany, identified a compound that inhibits the growth of such tumors and improves nerve function.

21 Sep 2020

Lopinavir-ritonavir does not suppress SARS-CoV-2 activity in vitro

Among them is the combination of lopinavir and ritonavir, which have been in use in an attempt to reduce the severity of the disease. However, a new South Korean study published on the preprint server bioRxiv in September 2020 shows that this combination is ineffective against the virus.

20 Sep 2020

Ziath introduces new products to assist compound management labs using Acoustix tubes

Ziath has released a module to enable their Mirage, Cube or Express tube readers to decode Brooks Acoustix tubes.

From Ziath Ltd 18 Sep 2020

Scientists investigate how psychedelic drugs interact with brain cells at the molecular level

Psychedelic drugs such as LSD, psilocybin, and mescaline cause severe and often long-lasting hallucinations, but they show great potential in treating serious psychiatric conditions, such as major depressive disorder.

18 Sep 2020

New drug candidate suppresses SARS-CoV-2 replication

Researchers at Stanford University and Utah State University have developed a novel inhibitor of the coronavirus main protease (Mpro) that effectively suppresses the viral replication of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

17 Sep 2020

Could pineapples be a new weapon against COVID-19?

Results of a recent research endeavor from the United States indicate that bromelain or bromelain rich pineapple stem may be utilized as an antiviral agent against coronavirus disease (COVID-19), but also for potential future coronavirus outbreaks. This exciting paper is currently available on the bioRxiv preprint server.

17 Sep 2020

Ceftazidime flagged as a potential inhibitor of the SARS-COV-2 virus

After screening more than 3,500 FDA-approved drugs and small molecules, researchers at the Chinese Academy of Sciences found that ceftazidime, an antibiotic approved for use in treating pneumonia, binds to the receptors that the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) binds to in human cells.

17 Sep 2020

Prolonged loneliness may influence the development of type 2 diabetes

Published in the journal Diabetologia (the journal of the European Association for the Study of Diabetes [EASD]), the study shows that it is the absence of quality connections with people and not the lack of contact that predicts the onset of type 2 diabetes, suggesting that helping people form and experience positive relationships could be a useful tool in prevention strategies for type 2 diabetes.

15 Sep 2020

Researchers develop new PET imaging agent that spotlights inflammation

Many of the most common diseases -- cancer, diabetes, cardiovascular and lung disease, and even COVID-19 -- have been linked to chronic or excessive inflammation.

14 Sep 2020

Yale researchers identify possible treatment for Duchenne muscular dystrophy

Researchers at Yale have identified a possible treatment for Duchenne muscular dystrophy (DMD), a rare genetic disease for which there is currently no cure or treatment, by targeting an enzyme that had been considered "undruggable."

12 Sep 2020

Compound News and Research

Researchers use natural pigment for screening cell viability

Automated computational protocol identifies potential SARS-CoV-2 MPro inhibitor

Polyphenolic compound offers new therapeutic option for chronic inflammatory disorders

Gruthan Bioscience to develop new class of cholesterol-lowering drugs

Chaperone-mediated autophagy could be a new therapeutic target for spinocerebellar ataxia

SGD Pharma introduces Ensiemo, the new complete child-resistant packaging solution for CBD oils

Owlstone Medical releases positive study results on use of breath biopsy for better liver disease diagnosis

Phase 2 clinical trial to examine the effects of razuprotafib on COVID-19 patients

Researchers identify a potential drug candidate for hand, foot and mouth disease

Genomic adaptations to rice‐based diets contribute to mitigation of metabolic risk

Researchers identify a compound that inhibits growth of schwannomas

Lopinavir-ritonavir does not suppress SARS-CoV-2 activity in vitro

Ziath introduces new products to assist compound management labs using Acoustix tubes

Scientists investigate how psychedelic drugs interact with brain cells at the molecular level

New drug candidate suppresses SARS-CoV-2 replication

Could pineapples be a new weapon against COVID-19?

Ceftazidime flagged as a potential inhibitor of the SARS-COV-2 virus

Prolonged loneliness may influence the development of type 2 diabetes

Researchers develop new PET imaging agent that spotlights inflammation

Yale researchers identify possible treatment for Duchenne muscular dystrophy

Advancing therapeutic biopolymer development eBook

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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