Gene Expression News and Research

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Gene Expression is the process by which a gene gets turned on in a cell to make RNA and proteins. Gene expression may be measured by looking at the RNA, or the protein made from the RNA, or what the protein does in a cell.

Three different autism risk genes found to have similar effects on brain development

Autism spectrum disorder has been associated with hundreds of different genes, but how these distinct genetic mutations converge on a similar pathology in patients has remained a mystery.

2 Feb 2022

UCLA researchers develop first human genomic transgenic mouse model of Huntington's disease

Researchers at the Jane and Terry Semel Institute for Neuroscience and Human Behavior at UCLA and the David Geffen School of Medicine at UCLA have developed a new mouse model of Huntington's disease that recapitulates more Huntington's disease-like characteristics than earlier models.

2 Feb 2022

CECR2 gene inhibition prevents triple-negative breast cancer from metastasizing, study shows

A new study by researchers at Yale Cancer Center shows inhibition of the CECR2 gene prevents triple-negative breast cancer from advancing or metastasizing.

2 Feb 2022

Researchers discover mechanism behind loss of smell in people with COVID-19

Researchers have discovered a mechanism that may explain why people with COVID-19 lose their sense of smell.

2 Feb 2022

TTUHSC project awarded new NIH grant to advance research on amygdala pain mechanisms

It is estimated that more than 100 million U.S. adults are affected by chronic pain, a condition that annually costs the country an estimated $560-635 billion in health care costs, disability and lost productivity.

1 Feb 2022

SARS-CoV-2 protein NSP2 found to impair microRNA-induced gene silencing in human cells

In a new study, a team of researchers used co-immunoprecipitation and in vitro interaction assays to identify the molecular basis of interaction of SARS-CoV-2 non-structural protein 2 with eIF4E-homologous protein (4EHP)-GRB10-interacting glycine-tyrosine-phenylalanine domain protein 2 complex, involved in microRNA-mediated gene silencing in human cells.

1 Feb 2022

Study identifies drugs that could help combat mortality in patients with COVID-19

Inflammation is a defense mechanism of the body to fight pathogens. However, when it is widespread and excessive, it can aggravate the pathology and even cause death.

31 Jan 2022

Damon Runyon Cancer Research Foundation announces newest cohort of Fellows and Breakthrough Scientists

The Damon Runyon Cancer Research Foundation has announced its newest cohort of Damon Runyon Fellows, 13 outstanding postdoctoral scientists conducting basic and translational cancer research in the laboratories of leading senior investigators.

29 Jan 2022

New approach accelerates the detection of cancer biomarkers for point-of-care diagnostics

The detection and quantification of cancer-associated molecular biomarkers in body fluids, or liquid biopsies, prove minimally invasive in early cancer diagnostics.

29 Jan 2022

New atlas characterizes immune cells that play a role in hemorrhagic stroke

In work that will enhance the study of such disparate diseases as stroke and dementia, researchers at UC San Francisco have catalogued all the cells that form the blood vessels of the human brain, along with their locations and the genes transcribed in each.

28 Jan 2022

Predicting pregnancy health and preeclampsia risk with blood RNA sequencing

In this interview, News-Medical speaks to Dr. Thomas McElrath about his latest research into a maternal-fetal medicine technique for predicting pregnancy health.

27 Jan 2022

Diet leaves permanent genetic alterations in the gut microbes

Our gut is inhabited by a diverse community of microbes, the gut microbiota. This community, composed of hundreds of different species, is essential to our health: it influences our immune system, protects us from infections, and helps us digest food.

27 Jan 2022

Drug combo delivered in a nanoparticle formulation extends the survival of mice with medulloblastoma

UNC Lineberger Comprehensive Cancer Center researchers have demonstrated that a novel combination of two drugs that act as targeted inhibitors, delivered in a nanoparticle formulation, extend the survival of mice with medulloblastoma.

27 Jan 2022

Study helps understand how smoking can lead to an increased risk of heart attacks

Smoking cigarettes may increase the risk of a heart attack by activating a gene that affects blood clotting, according to a new study by scientists at the University of Bristol.

26 Jan 2022

Study demonstrates differential alternative splicing in betacoronaviruses

A new study investigates whether the proportion of ribosomal genes displaying differential gene expression and differential alternative splicing differed between three betacoronaviruses and six other viruses and bacteria.

26 Jan 2022

Study finds overexpression of 3 SARS-CoV-2 genes could globally compromise transcriptome of human pluripotent stem cell-derived cardiomyocytes

In a recent study, whole mRNA-seq was used to investigate the global effects of SARS-CoV-2 viral genes Nsp6, Nsp8, and M on the transcriptome of hPSC-CMs.

26 Jan 2022

Understanding immune responses to SARS-CoV-2 infections in children

A study published in the journal Immunity analyzed the varied manifestations of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in children.

26 Jan 2022

Cannabidiol inhibits SARS-CoV-2 replication in human cells and mice

In research recently published in the journal of Science Advances, an interdisciplinary team of researchers from the University of Chicago assessed the potential role of cannabidiol (CBD), a natural product extracted from the cannabis plant, to prevent and inhibit severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections in human cells and mice.

26 Jan 2022

Spike-mediated CFTR inhibition accounts for airway inflammation in COVID-19

A new study looks at the molecular level inhibition of the protective CFTR gene by the SARS-CoV-2 spike protein.

25 Jan 2022

Researchers develop a computational approach to identify genomic safe harbors for therapeutic genes

Many future gene and cell therapies to treat diseases like cancer, rare genetic and other conditions could be enhanced in their efficacy, persistence, and predictability by so-called "genomic safe harbors (GSHs)."

24 Jan 2022

Gene Expression News and Research

Further Reading

Three different autism risk genes found to have similar effects on brain development

UCLA researchers develop first human genomic transgenic mouse model of Huntington's disease

CECR2 gene inhibition prevents triple-negative breast cancer from metastasizing, study shows

Researchers discover mechanism behind loss of smell in people with COVID-19

TTUHSC project awarded new NIH grant to advance research on amygdala pain mechanisms

SARS-CoV-2 protein NSP2 found to impair microRNA-induced gene silencing in human cells

Study identifies drugs that could help combat mortality in patients with COVID-19

Damon Runyon Cancer Research Foundation announces newest cohort of Fellows and Breakthrough Scientists

New approach accelerates the detection of cancer biomarkers for point-of-care diagnostics

New atlas characterizes immune cells that play a role in hemorrhagic stroke

Predicting pregnancy health and preeclampsia risk with blood RNA sequencing

Diet leaves permanent genetic alterations in the gut microbes

Drug combo delivered in a nanoparticle formulation extends the survival of mice with medulloblastoma

Study helps understand how smoking can lead to an increased risk of heart attacks

Study demonstrates differential alternative splicing in betacoronaviruses

Study finds overexpression of 3 SARS-CoV-2 genes could globally compromise transcriptome of human pluripotent stem cell-derived cardiomyocytes

Understanding immune responses to SARS-CoV-2 infections in children

Cannabidiol inhibits SARS-CoV-2 replication in human cells and mice

Spike-mediated CFTR inhibition accounts for airway inflammation in COVID-19

Researchers develop a computational approach to identify genomic safe harbors for therapeutic genes

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