Molecule News and Research

RSS

Researchers discover key epigenetic alteration associated with clinical course of liver cancer

Researchers at the Josep Carreras Leukaemia Research Institute, led by Dr. Manel Esteller, have discovered a key epigenetic alteration that anticipates the clinical course of liver cancer.

16 May 2023

Researchers report the role of RNA-binding protein Msi 1 to maintain breast cancer stem cells

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 9, entitled, "Increased expression of musashi 1 on breast cancer cells has implication to understand dormancy and survival in bone marrow."

16 May 2023

LabGenius Debuts T-cell Engager Optimisation Capability That Yields Molecules with >400-fold Tumour Killing Selectivity Versus Clinical Benchmark

Through a recent platform demonstration project, LabGenius’ machine learning-driven lead optimisation capability delivered dozens of novel T-cell engagers with best-in-class killing selectivity.

From LabGenius 16 May 2023

Research sheds light on potential application of cyclodextrin derivatives in drug-supersaturated formulations

In the medicine market, most newly introduced drugs and drug candidates show poor water solubility, which prevents their absorption in the body.

15 May 2023

New compound with antibacterial activity shows promising results within one hour in laboratory trials

Resistance to antibiotics is a problem that alarms the medical and scientific community. Bacteria resistant to three different classes of antibiotics, known as multi-drug resistant (MDR) bacteria, are far from rare.

15 May 2023

Study reveals how serotonin affects animal behavior at the whole-brain scale

Because serotonin is one of the primary chemicals the brain uses to influence mood and behavior, it is also the most common target of psychiatric drugs.

15 May 2023

Phase 1 clinical trial of CAR-NKT cell therapy shows promising results in neuroblastoma patients

Researchers at Baylor College of Medicine/Texas Children's Cancer Center and collaborating institutions report interim results from a first-in-human phase 1 clinical trial evaluating the safety, antitumor activity and immunological characteristics of a genetically engineered natural killer T (NKT) cell immunotherapy for neuroblastoma, a childhood tumor that most commonly arises in the adrenal gland.

15 May 2023

Creating the Lab of the Future; What does it entail?

As part of our SLAS US 2023 coverage, we speak to Luigi Da Via, Team Leader in Analytical Development at GSK, about the lab of the future, and what it may look like.

From Society for Laboratory Automation and Screening (SLAS) 15 May 2023

Study offers hope for better recovery of stroke patients

Ischemic stroke, caused by a blockage of blood flow to the brain, is a common cause of death and disability.

11 May 2023

New drug delivery system delivers antioxidant directly to mitochondria in the liver

A new drug delivery system delivers an antioxidant directly to mitochondria in the liver, mitigating the effects of oxidative stress.

10 May 2023

Leveraging proteomics datasets to discover potential therapeutic targets for cancer patients

A new research perspective was published in Oncotarget's Volume 14 on May 4, 2023, entitled, "Using cancer proteomics data to identify gene candidates for therapeutic targeting."

10 May 2023

New AI-powered, laser-based breathalyzer can detect COVID-19 in real-time

With each breath, humans exhale more than 1,000 distinct molecules, producing a unique chemical fingerprint or "breathprint" rich with clues about what's going on inside the body.

10 May 2023

Sodium showdown: How the food service industry battles salt to make America healthier

Research paper discusses the challenges faced by the food service industry in reducing sodium content in foods prepared and consumed away from home (FAFH), as well as successful strategies used to reduce sodium in FAFH.

10 May 2023

New SNAP approach to customizing T cell-based immunotherapies

University of Pittsburgh researchers have developed a universal receptor system that allows T cells to recognize any cell surface target, enabling highly customizable CAR T cell and other immunotherapies for treating cancer and other diseases.

9 May 2023

Military personnel exposed to explosions show abnormal amyloid accumulation in the brain

New research finds that the brains of otherwise healthy military personnel who are exposed to explosions show an abnormal brain accumulation of amyloid-beta protein - a protein that plays a role in the development of Alzheimer's disease.

9 May 2023

Boosting gut health with short-chain fatty acids

Research paper provides an overview of short-chain fatty acids (SCFAs) and their role in regulating gut homeostasis. It also discusses SCFA-producing bacteria and potential therapeutic approaches to boost SCFA levels in the gut to treat related diseases.

9 May 2023

New toolkit enables in-vivo cross-linking of protein complexes in live cells

As the executor of life activities, proteins exert their specific biological functions through interactions such as forming protein complexes.

9 May 2023

Ultra-long protein fibrils are a signature of severe Alzheimer’s disease, study shows

During the course of Alzheimer's disease, protein fibrils appear in the spinal fluid of affected individuals. Empa researchers, together with the Department of Neurology at the Cantonal Hospital in St. Gallen, have now visualized the wide spectrum of protein aggregates from oligomers, protofibrils to fibrils in the spinal fluid.

9 May 2023

New small-molecule drugs show potential clinical utility in treating world’s leading causes of blindness

In a University of California, Irvine-led study, researchers have discovered small-molecule drugs with potential clinical utility in the treatment of age-related macular degeneration (AMD), diabetic retinopathy (DR), and retinitis pigmentosa (RP).

9 May 2023

Anticoronavirals: the development of COVID-19 therapies and the challenges that remain

Researchers highlighted the pace of development of COVID-19 therapies during the pandemic and the challenges that hinder the widespread availability of anticoronavirals.

8 May 2023

Molecule News and Research

Researchers discover key epigenetic alteration associated with clinical course of liver cancer

Researchers report the role of RNA-binding protein Msi 1 to maintain breast cancer stem cells

LabGenius Debuts T-cell Engager Optimisation Capability That Yields Molecules with >400-fold Tumour Killing Selectivity Versus Clinical Benchmark

Research sheds light on potential application of cyclodextrin derivatives in drug-supersaturated formulations

New compound with antibacterial activity shows promising results within one hour in laboratory trials

Study reveals how serotonin affects animal behavior at the whole-brain scale

Phase 1 clinical trial of CAR-NKT cell therapy shows promising results in neuroblastoma patients

Creating the Lab of the Future; What does it entail?

Study offers hope for better recovery of stroke patients

New drug delivery system delivers antioxidant directly to mitochondria in the liver

Leveraging proteomics datasets to discover potential therapeutic targets for cancer patients

New AI-powered, laser-based breathalyzer can detect COVID-19 in real-time

Sodium showdown: How the food service industry battles salt to make America healthier

New SNAP approach to customizing T cell-based immunotherapies

Military personnel exposed to explosions show abnormal amyloid accumulation in the brain

Boosting gut health with short-chain fatty acids

New toolkit enables in-vivo cross-linking of protein complexes in live cells

Ultra-long protein fibrils are a signature of severe Alzheimer’s disease, study shows

New small-molecule drugs show potential clinical utility in treating world’s leading causes of blindness

Anticoronavirals: the development of COVID-19 therapies and the challenges that remain

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Latest News