Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Molecular tumor profiling in pediatric cancer patients significantly impacts clinical care

Results of a study of molecular tumor profiling in young patients revealed a high rate of genetic alterations with potential for impacting clinical care, including clarifying diagnoses and treatment with matched, precision cancer drugs.

23 Jun 2022

Novel liquid biopsy test can quickly identify cancer DNA in patients with metastatic breast cancer

A novel, automated liquid biopsy test in development by researchers at the Johns Hopkins Kimmel Cancer Center can accurately detect the presence of cancer DNA in the blood of patients with metastatic breast cancer within five hours.

23 Jun 2022

FUJIFILM Corporation Commit Themselves to Digital Pathology

FUJIFILM Corporation is at the forefront of the digital histopathology revolution, centered around the Dynamyx™ software by Inspirata, and supported by genuine partnerships that drive improvements in patient care.

From FUJIFILM Corporation 22 Jun 2022

Medical societies publish guidelines on how to treat pre-invasive lesions of the vulva

Four international medical societies have collaborated on consensus statements for physicians, published in the Journal of Lower Genital Tract Disease, about how to treat pre-invasive lesions of the vulva.

21 Jun 2022

Research may pave the way for a future test to diagnose ALS

Amyotrophic lateral sclerosis (ALS) is a progressive disease of the nervous system. It affects nerve cells in the brain and spinal cord called motor neurons.

21 Jun 2022

SARS-CoV-2 infection may be a trigger of myelin oligodendrocyte glycoprotein-associated disorder

A new study reported four cases of Myelin Oligodendrocyte Glycoprotein-Associated Disorder that commenced after SARS-CoV-2 infection.

21 Jun 2022

New combination of drugs effective against T-cell acute lymphoblastic leukemia

Acute lymphoblastic leukemia (ALL) is the most common cancer affecting children. The T-ALL form of leukemia that emerges from early T lineage cells has a poorer prognosis than B-lineage ALL. The prognosis for relapsed T-ALL is very poor and new therapies are sorely needed.

20 Jun 2022

Traumatic brain injury changes the connections between nerve cells across the entire brain

Scientists from the University of California, Irvine have discovered that an injury to one part of the brain changes the connections between nerve cells across the entire brain.

17 Jun 2022

Researchers investigate COVID fog and chemokine C–C motif ligand 11

Researchers assessed the characteristics of the brain fog reported by some COVID-19 patients.

17 Jun 2022

Combination drug strategy activates natural killer cell-mediated immunity to attack tumors

Most skin cancer drugs that activate the immune system work by triggering immune cells, called T cells, to attack tumors, but when T cells are activated for too long, they can wear out and cease to function.

16 Jun 2022

Study reveals sex differences in COVID-19 diagnosis at the start of the pandemic

University of Alicante Professor of Preventive Medicine and Public Health María Teresa Ruiz Cantero has prepared a study based on COVID-19 and gender biases in healthcare and the inequalities revealing sex differences, recently presented as part of the 2022 Gender and Health Report of the Spanish Ministry of Health, through the Women's Health Observatory.

16 Jun 2022

Even mild respiratory COVID can affect the brain

In a recent study published in the journal Cell, researchers explored neurological symptoms and subsequent cognitive impairment experienced by survivors of mild respiratory coronavirus disease 2019 (COVID-19).

14 Jun 2022

Temple researcher receives NIH award to study the link between HIV, substance use and heart disease

With prompt diagnosis and the right treatment, people with HIV can live long, healthy lives. In recent years, however, gains in survival among people with HIV have exposed a new concern – an increase in the incidence of early-onset cardiovascular disease associated with long-term HIV.

14 Jun 2022

Targeting macropinocytosis may be an effective therapeutic approach for hepatocellular carcinoma

Researchers from the Department of Pathology, School of Clinical Medicine, LKS Faculty of Medicine, The University of Hong Kong (HKUMed) have identified a new metabolic mechanism in liver cancer cells, by which macropinocytosis, an endocytic process, is used to engulf extracellular proteins as fuels to support the unlimited growth of hepatocellular carcinoma (HCC) in hypoxia (oxygen deprivation).

14 Jun 2022

New research provides credible estimates for prevalence of Alzheimer’s-like brain disorder

New National Institutes of Health-funded research shows that the prevalence of brain changes from Limbic-predominant Age-related TDP-43 Encephalopathy (LATE) may be roughly 40% in older adults and as high as 50% in people with Alzheimer's disease.

13 Jun 2022

Study provides the most definitive assessment of new non-Alzheimer’s dementia

Researchers from the University of Kentucky's Sanders-Brown Center on Aging say a paper recently published in Acta Neuropathologica is the most definitive assessment yet of the prevalence of a form of dementia classified in 2019 and now known as LATE.

13 Jun 2022

Social stress factors have a direct impact on cellular mechanisms that drive deadly breast cancer

Chronically stressful conditions of daily life such as racism, pollution and poverty have a direct impact on the cellular mechanisms that drive lethal, invasive forms of breast cancer, according to a study led by Duke Cancer Institute researchers.

13 Jun 2022

Proteomic analysis of 2002 tumors reveals 11 distinct pan-cancer molecular subtypes

A new study that analyzed protein levels in 2,002 primary tumors from 14 tissue-based cancer types identified 11 distinct molecular subtypes, providing systematic knowledge that greatly expands a searchable online database that has become a go-to platform for cancer data analysis by users worldwide.

10 Jun 2022

Older adults with Type 1 diabetes have greater risk for muscle weakening, cardiovascular complications

Older adults with Type 1 diabetes (T1D) are at significantly higher risk of both muscle weakening and cardiovascular complications, say McMaster University researchers.

10 Jun 2022

Association of neuronal and non-neuronal GABA with neuropsychiatric illness in COVID-19 patients

A new study published in the journal Reports focused on the hijacking of the pancreatic, endothelial, and gut GABA by SARS-CoV-2 and its associated pathology along with interventions.

10 Jun 2022

Pathology News and Research

Further Reading

Molecular tumor profiling in pediatric cancer patients significantly impacts clinical care

Novel liquid biopsy test can quickly identify cancer DNA in patients with metastatic breast cancer

FUJIFILM Corporation Commit Themselves to Digital Pathology

Medical societies publish guidelines on how to treat pre-invasive lesions of the vulva

Research may pave the way for a future test to diagnose ALS

SARS-CoV-2 infection may be a trigger of myelin oligodendrocyte glycoprotein-associated disorder

New combination of drugs effective against T-cell acute lymphoblastic leukemia

Traumatic brain injury changes the connections between nerve cells across the entire brain

Researchers investigate COVID fog and chemokine C–C motif ligand 11

Combination drug strategy activates natural killer cell-mediated immunity to attack tumors

Study reveals sex differences in COVID-19 diagnosis at the start of the pandemic

Even mild respiratory COVID can affect the brain

Temple researcher receives NIH award to study the link between HIV, substance use and heart disease

Targeting macropinocytosis may be an effective therapeutic approach for hepatocellular carcinoma

New research provides credible estimates for prevalence of Alzheimer’s-like brain disorder

Study provides the most definitive assessment of new non-Alzheimer’s dementia

Social stress factors have a direct impact on cellular mechanisms that drive deadly breast cancer

Proteomic analysis of 2002 tumors reveals 11 distinct pan-cancer molecular subtypes

Older adults with Type 1 diabetes have greater risk for muscle weakening, cardiovascular complications

Association of neuronal and non-neuronal GABA with neuropsychiatric illness in COVID-19 patients

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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