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Single dose of osanetant reduces fear response in female mice after trauma

A new Brevia (peer-reviewed research report) published in Brain Medicine reveals that a single dose of the drug Osanetant, administered shortly after a traumatic event, significantly dampens fear expression in female mice.

8 Apr 2025

Proteins linked to Parkinson's and ALS found to protect mitochondria

Scientists at Johns Hopkins Medicine say they have discovered how a group of proteins linked to Parkinson's disease and amyotrophic lateral sclerosis act as "guardians" of mitochondria, small organelles, or subunits, within a cell that make and store energy and are found in almost all plants and animals.

8 Apr 2025

New studies reveal how cytokines affect mood and behavior

Physicians have long observed a mystifying phenomenon: After a bout of infection or an autoimmune disease flare-up, some people experience prolonged mood swings, emotional dysregulation, and changes in behavior.

7 Apr 2025

Vitamin C from fresh foods helps lower heart disease risk in type 2 diabetes

Low vitamin C levels are linked to higher cardiovascular disease prevalence in people with type 2 diabetes. Fresh fruit and vegetable intake is associated with higher vitamin C levels and may offer protective cardiovascular effects.

7 Apr 2025

Bone aging is more complex than previously thought

A new research paper was published in Aging (Aging-US) on March 18, 2025, in Volume 17, Issue 3, titled "Mitochondrial oxidative stress or decreased autophagy in osteoblast lineage cells is not sufficient to mimic the deleterious effects of aging on bone mechanoresponsiveness."

7 Apr 2025

Scientists discover cellular mechanism to protect and repair mitochondria

Damage to the genetic material of mitochondria – the mitochondrial DNA or mtDNA for short – can lead to diseases such as Parkinson's, Alzheimer's, amyotrophic lateral sclerosis (ALS), cardiovascular diseases and type 2 diabetes.

4 Apr 2025

Immigration crackdowns disrupt the caregiving industry. Families pay the price.

Alanys Ortiz reads Josephine Senek's cues before she speaks. Josephine, who lives with a rare and debilitating genetic condition, fidgets her fingers when she's tired and bites the air when something hurts.

4 Apr 2025

Reducing cardiometabolic risk and inflammation with pomegranate

Pomegranate extract shows promise in lowering systolic blood pressure and inflammatory markers, highlighting its role in promoting healthy aging for adults 55+.

4 Apr 2025

Study identifies 17 modifiable risk factors shared between stroke, dementia, and depression

Age-related brain diseases such as stroke, dementia, and late-life depression are a debilitating part of growing older, but people can lower their risk of these diseases through behavioral and lifestyle changes.

3 Apr 2025

Study links neurotensin deficiency to ovulatory dysfunction in PCOS

Polycystic ovary syndrome (PCOS) represents a significant health concern for women of reproductive age, manifesting as a complex endocrine disorder with diverse clinical presentations.

3 Apr 2025

Bach2 protein identified as key regulator in atopic dermatitis

Atopic dermatitis is an allergy affecting approximately 10% of the Japanese population, with symptoms closely related to social stress.

3 Apr 2025

Trump’s DEI undoing undermines hard-won accommodations for disabled people

For years, White House press conferences included sign language interpreters for the deaf.

3 Apr 2025

Wealth inequality drives higher US mortality compared to Europe

Comparing wealth and survival rates in the U.S. with those in Europe, researchers found that over a 10-year period, Americans across all wealth levels were more likely to die than their European counterparts.

3 Apr 2025

Experts develop new guidelines for the treatment of schizophrenia

New guidelines have been developed for the treatment of schizophrenia after a collaboration of international experts from 30 countries.

2 Apr 2025

Fat cells trigger liver stress through secreted lipids

The endoplasmic reticulum (ER) is the portion of the cell responsible for manufacturing and folding proteins.

2 Apr 2025

New drug shows neuroprotective and anti-inflammatory effects in murine models of Alzheimer's

Alzheimer's disease, the most common cause of dementia, is currently incurable. The current drugs available have very limited efficacy and only in mild stages of the disease.

2 Apr 2025

Cedars-Sinai study investigates diet's role in treating gut disorders

A new study from Cedars-Sinai examined whether a specialized diet could improve symptoms of gastrointestinal disorders linked to an imbalance in gut microbiota.

1 Apr 2025

Hydrogel-based drug delivery offers hope for post-traumatic osteoarthritis

Post-traumatic osteoarthritis (PTOA) is a condition that affects joints after an injury. Current treatments focus on relieving symptoms but do not prevent or stop the progression of the condition.

1 Apr 2025

Emotional fear acts as a barrier to constructive communication among partners with PTSD

People with post-traumatic stress disorder (PTSD) symptoms often have trouble communicating and resolving relationship difficulties with their romantic partners, according to previous research by Steffany Fredman, associate professor of human development and family studies at Penn State, and others.

1 Apr 2025