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5,000 rare diseases need drugs, but Europe only approves a handful each year

Only seven per cent of drug applications for treating people with rare diseases were approved in Europe between 2000 and 2004, despite the fact that there are currently more than 5,000 conditions needing medication.

6 Mar 2006

UCB submits application to FDA for new treatment in Crohn's disease

UCB has announced the submission of a Biologics License Application (BLA) to the United States Food and Drug Administration (FDA) for the approval of CIMZIA (certolizumab pegol, CDP870) for the treatment of patients with Crohn's disease.

6 Mar 2006

FDA grants priority review for Revlimid

Celgene Corporation announced that the U.S. Food and Drug Administration (FDA) has granted a Priority Review designation to its Supplemental New Drug Application (sNDA) for REVLIMID (lenalidomide) for the treatment of relapsed or refractory multiple myeloma.

6 Mar 2006

Study shows Differin Gel works well in combination with systemic or other topical agents

Findings from the M.O.R.E. (Measuring Outcomes in A Real World Experience) Trial presented at the 64th annual meeting of the American Academy of Dermatology (AAD) show that Differin Gel 0.1% is a topical retinoid preparation that, when combined with other acne products, dramatically improves the efficacy of an acne regimen.

6 Mar 2006

New neoprene suit helps save the lives of women suffering from obstetrical hemorrhaging due to childbirth

A simple, low-tech garment has the potential to prevent a major cause of death among women who give birth in many Third World countries, according to a new study by maternal health researchers.

1 Mar 2006

Celebrex safe for osteoarthritis

According to a study by Stanford University School of Medicine, Celebrex causes fewer gastrointestinal complications than traditional nonsteroidal anti-inflammatory painkillers or NSAIDs in osteoarthritis patients and does not increase the risk of heart attacks.

1 Mar 2006

Xenon gas shown to be safe in surgery and could help stop nervedamaging illnesses

Scientists have successfully conducted the first clinical trial giving xenon gas to patients undergoing coronary artery bypass grafting in order to safeguard against postoperative brain damage that can occur following this procedure.

27 Feb 2006

Methotrexate re-use in rheumatoid arthritis is frequently effective despite earlier failures

A second course of methotrexate, the most commonly used drug to treat rheumatoid arthritis, is effective in nearly half of studied patients for whom a previous treatment with the drug was ineffective.

27 Feb 2006

Combination therapy improves Acquired Immunodeficiency Syndrome-Related Lymphoma outcome

Combining aggressive HIV therapy and chemotherapy significantly improves the survival rates of HIV-positive men and women treated for lymphoma, according to a new study.

27 Feb 2006

Coronary stents that release the drugs sirolimus or paclitaxel produce similar results

Use of coronary stents that release the drugs sirolimus or paclitaxel produced similar results in patients with new coronary artery lesions, according to a study in JAMA: The Journal of the American Medical Association.

24 Feb 2006

HIV/AIDS risks reduced when mothers educate daughters

Low-income African American teen girls in Chicago continue to be at high risk for contracting HIV, but the risk decreases when their mothers teach them about the dangers of the disease, according to a new study at the University of Illinois at Chicago.

24 Feb 2006

Efficacy of glucosamine, chondroitin sulfate may depend on level of osteoarthritis pain

The popular dietary supplements glucosamine and chondroitin sulfate proved no better than a placebo in relieving osteoarthritis knee pain in most participants of a major national trial.

23 Feb 2006

Glucosamine/Chondroitin combo helps those with moderate to severe joint pain

According to a new study by the National Institutes of Health, people with moderate to severe joint discomfort found that a combination of glucosamine and chondroitin resulted in significant pain and function improvement.

23 Feb 2006

New oral vaccine against Pseudomonas aeruginosa

A new oral vaccine against Pseudomonas aeruginosa, a bacterium commonly known for afflicting patients with lung dysfunction, has shown to protect healthy human volunteers from infection say researchers from England and Australia.

23 Feb 2006

External counterpulsation not effective as a treatment for heart failure

A new review of studies supports the government's opinion that too little evidence exists to support a device that uses balloon-like pants as a treatment for heart failure.

23 Feb 2006

Extract from Scutellaria Barbata may treat breast cancer

A new clinical formulation extracted from a botanical may provide physicians with a new tool in treating aggressive late-stage breast cancer.

21 Feb 2006

Pfizer receives FDA approval for Eraxis to treat candidemia

Pfizer said today that Eraxis (anidulafungin) has been approved by the U.S. Food and Drug Administration to treat candidemia, a potentially life-threatening bloodstream infection. Candidemia is the most deadly of the common hospital-acquired bloodstream infections, with a mortality rate of approximately 40 percent.

21 Feb 2006

Lung-volume reduction surgery is a good option for many patients with end-stage emphysema

Tens of thousands of Americans living with emphysema would benefit from a surgical procedure that removes part of the lung, according to national research presented by a Saint Louis University cardiothoracic surgeon.

21 Feb 2006

Rimonabant produces sustained weight loss long term

Use of the weight-loss medication rimonabant produced modest yet sustained weight loss after 2 years, and improved HDL cholesterol and triglyceride levels, according to a study in the February 15 issue of JAMA: The Journal of the American Medical Association.

17 Feb 2006

Topical anaesthesia and morphine effective in treating procedural pain in newborn infants

Researchers at The Hospital for Sick Children (SickKids) have found that intravenous morphine used alone or with a topical anaesthetic (tetracaine) effectively reduced levels of pain in newborn infants undergoing insertion of central venous catheters (central lines).

17 Feb 2006

Efficacy News and Research

5,000 rare diseases need drugs, but Europe only approves a handful each year

UCB submits application to FDA for new treatment in Crohn's disease

FDA grants priority review for Revlimid

Study shows Differin Gel works well in combination with systemic or other topical agents

New neoprene suit helps save the lives of women suffering from obstetrical hemorrhaging due to childbirth

Celebrex safe for osteoarthritis

Xenon gas shown to be safe in surgery and could help stop nervedamaging illnesses

Methotrexate re-use in rheumatoid arthritis is frequently effective despite earlier failures

Combination therapy improves Acquired Immunodeficiency Syndrome-Related Lymphoma outcome

Coronary stents that release the drugs sirolimus or paclitaxel produce similar results

HIV/AIDS risks reduced when mothers educate daughters

Efficacy of glucosamine, chondroitin sulfate may depend on level of osteoarthritis pain

Glucosamine/Chondroitin combo helps those with moderate to severe joint pain

New oral vaccine against Pseudomonas aeruginosa

External counterpulsation not effective as a treatment for heart failure

Extract from Scutellaria Barbata may treat breast cancer

Pfizer receives FDA approval for Eraxis to treat candidemia

Lung-volume reduction surgery is a good option for many patients with end-stage emphysema

Rimonabant produces sustained weight loss long term

Topical anaesthesia and morphine effective in treating procedural pain in newborn infants

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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