Lymph Node News and Research

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Lymph is clear or white fluid that travels through vessels, moves within tissues and work to keep all the parts of the body clean. After passing through the channels of the lymphatic system they drain into the lymph nodes. The lymph nodes act as filters along the lymphatic system. These nodes trap germs like bacteria, viruses, toxins as well as cancer cells and ensure that these are removed from the body.

No evidence related to transferability of biomarker tests for decision-making on chemotherapy for breast cancer

Following a benefit assessment in 2016 and an addendum in 2018, the German Institute for Quality and Efficiency in Health Care has again examined biomarker-based tests for women with primary breast cancer.

7 Mar 2020

Aggressive features in papillary thyroid microcarcinoma raises the risk for distant metastasis

Although papillary thyroid carcinoma is the most common form of thyroid malignancy, it is considered to be an indolent disease that progresses slowly and has an excellent prognosis.

6 Mar 2020

New type of adoptive cell therapy could target prostate and pancreatic cancers in humans

In experiments with mice, researchers at the Johns Hopkins Kimmel Cancer Center say they have slowed the growth of transplanted human prostate and pancreatic cancer cells by introducing bone marrow cells with a specific gene deletion to induce a novel immune response.

5 Mar 2020

Study provides new evidence about optimal way to treat BRCA carriers with breast cancer

Commonly known as the breast cancer genes, the BRCA gene family plays a role in repairing damaged DNA. Inherited mutations in the genes BRCA1 or BRCA2 raise the risk of developing breast, ovarian, prostate and other cancers.

5 Mar 2020

UAH research could have broad implications for immunotherapy and cancer treatment

Research into engineering artificial organs that mimic the functions of human lymph nodes at The University of Alabama in Huntsville has garnered one of its professors a $507,777 National Science Foundation Faculty Early Career Development Program Award.

21 Feb 2020

Children with suspected appendicitis need better care, finds study

A new study published in the journal The Lancet Child & Adolescent Health reports that suspected appendicitis in children is not only among the most common pediatric conditions but often wrongly treated. The researchers found that literally, hundreds of children in the UK were having their appendices taken out unnecessarily.

13 Feb 2020

Researchers develop new isolated limb infusion method for melanoma treatment

Worldwide, the incidence rates of skin cancer, like other types of cancer, is increasing. People in Europe and the Nordic countries are, compared to other areas of the world, at a higher risk of developing skin cancer due to their predominantly light and sun-sensitive skin type. The number of new cases of cancer in Estonia and Nordic countries has reached the same level as in sunny Australia, New Zealand and Florida. The increasing trend among Estonians to travel to southern counties is also likely to play a role in this.

27 Jan 2020

Patient-specific tumor organoids may one day be used to personalize cancer treatment

A patient-specific tumor organoid platform developed by Wake Forest Institute for Regenerative Medicine researchers and their cancer center colleagues could someday take the guessing game out of immunotherapy treatments.

21 Jan 2020

Early-life disruption to lymphotoxin pathway in mice can compromise adult immunity to rotavirus

Researchers at the University of Toronto have discovered how a brief disruption to a molecular pathway in the guts of mice before they are born can compromise adult immunity to a common and often deadly intestinal virus.

22 Dec 2019

Researchers identify mechanism for spread of HIV-1

New insight on how a type of cell facilitates the spread of HIV-1 has been published today in the open-access journal eLife.

3 Dec 2019

Immunotherapy after CRT is safe in curative treatment of women with node-positive cervical cancer

Results from the NRG Oncology phase I clinical trial NRG-GOG 9929 show that utilizing the immunotherapy drug ipilimumab after chemoradiotherapy (CRT) is tolerated in the curative treatment of women with lymph node-positive cervical cancer.

2 Dec 2019

Russian scientists explain how an additional component can triple vaccine efficiency

A team of Russian scientists carried out a study on the cell immunity level and found out how an adjuvant called azoximer bromide increases the immunogenicity of the anti-flu vaccine.

12 Nov 2019

Drugs can be safely delivered to cancerous lymph nodes using sound waves

Drugs can be safely delivered to cancerous lymph nodes via the lymphatic system and then released inside the nodes using sound waves. Tohoku University researchers tested the treatment on mice with metastatic breast cancer and published their findings in the journal Scientific Reports.

28 Oct 2019

Phase 2 clinical trial of CAR T-cell therapy starts at Atlantic Health System

Atlantic Health System is treating patients in a new Phase 2 clinical trial of CAR T-cell therapy at Morristown Medical Center. A select number of sites across the U.S. are involved in this study, which is done on an outpatient basis.

25 Oct 2019

Older women with DCIS gain no benefit from sentinel lymph node biopsy

Older women with a very early, non-invasive breast cancer known as ductal carcinoma in situ (DCIS) gain no long-term benefit from undergoing a sentinel lymph node biopsy to see if the cancer has spread, new research by the Yale School of Public Health has found.

24 Oct 2019

Osaka University Hospital begins clinical research for prostate cancer diagnosis using PET imaging

Osaka University Hospital began Japan's first clinical research for diagnosis of prostate cancer using PET (positron emission tomography) scan results in September 2019.

7 Oct 2019

New prediction models for improved treatment of lymph nodes in breast cancer patients

In recently published studies, researchers at Lund University and Skåne University Hospital in Sweden have produced new prediction models for improved personalized treatment of lymph nodes in breast cancer patients.

20 Sep 2019

Scientists identify PoEMs that promote breast cancer metastasis

When breast cancer cells spread through the body, they do so mainly through the lymph system that normally removes excess fluid and waste products from our tissues.

28 Aug 2019

Nab-Paclitaxel drug combo reduces risk of breast cancer recurrence

A recent large German study has shown that a new combination therapy for breast cancer treatment leads to a lowered risk of the disease coming back. A commentary on this landmark clinical trial has been published in the latest issue of the Journal of Clinical Oncology by the researchers Masey Ross and Charles Geyer Jr. from the VCU Massey Cancer Center. The commentary was titled, “Nab-Paclitaxel: A New Standard of Care in Neoadjuvant Therapy of High-Risk Early Breast Cancer?”

27 Aug 2019

Researchers develop new strategy to target metastases in lymph nodes

Metastasis, in which cancer cells break free from the primary tumor and form tumors at other sites, worsens the prognosis for many cancer patients.

14 Aug 2019