Therapeutics News and Research

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HMGCR emerges as a promising target for precision cancer therapies

A growing body of evidence is reshaping how scientists and clinicians understand the role of cancer metabolism, placing the enzyme HMGCR at the center of a rapidly evolving therapeutic landscape.

5 Aug 2026

Cellular senescence drives progression of spinal disc degeneration and pain

A growing body of scientific insight is drawing attention to cellular senescence as a central force in the progression of intervertebral disc degeneration (IDD), a leading contributor to chronic low back pain worldwide.

5 Aug 2026

KCNE gene family emerges as a promising target for future precision medicine

A growing understanding of the KCNE gene family is reshaping how scientists view the regulation of electrical signaling across the human body, highlighting its essential role in maintaining normal physiological function and its connection to a wide range of diseases.

5 Aug 2026

Targeted dendritic cell vaccines emerge as a major step forward in cancer immunotherapy

A major step forward in cancer immunotherapy is emerging through the growing development of dendritic cell vaccines, a highly targeted approach designed to harness the body's own immune system to fight tumors.

5 Aug 2026

Review highlights the importance of miR-23b in shaping cancer development and progression

A new review highlights the growing importance of miR-23b, a small but powerful regulator of gene expression, in shaping the development and progression of a wide range of cancers.

5 Aug 2026

Versatile receptor protein plays critical role in regulating tissue repair

A comprehensive new review highlights the expanding importance of Lgr6, a member of the G protein-coupled receptor family, as a critical regulator of tissue homeostasis, injury repair, and disease development across multiple organ systems.

5 Aug 2026

Specialized selenoproteins play critical role in regulating cellular health

A new review highlights the remarkable importance of selenoproteins, a specialized group of molecules that, despite their small size, play a decisive role in shaping cellular fate and maintaining biological balance.

5 Aug 2026

Obscure X chromosome protein emerges as key driver in several cancers

A little-known protein encoded on the X chromosome is attracting growing attention for its potential role in cancer development and treatment.

5 Aug 2026

Intertwined cellular processes reshape understanding of diabetes

A deeper understanding of how key cellular processes interact is reshaping perspectives on diabetes and its wide-ranging complications.

5 Aug 2026

NIH funds research to explore the role of thymulin in inflammaging and cancer

As we age, chronic inflammation-or "inflammaging"-increases throughout the body and weakens our ability to fight cancer.

4 Aug 2026

AI tool helps customize radiopharmaceutical therapy dosing

Radiopharmaceutical therapy (RPT) has made great strides over the last 50 years, having only recently received FDA approval to treat prostate cancer. But despite the progress-and billions of dollars of industry investments-one area that has lagged behind is dosing, which is still one-size-fits-all.

4 Aug 2026

Cryo-EM study reveals dynamic structure of human norovirus

Human norovirus is the leading cause of acute gastroenteritis worldwide and is estimated to infect 600–700 million people each year.

4 Aug 2026

New genomic approach links rare immune cells to autoimmune disease risk

Much of how genetic risk leads to disease has remained hidden. In many cases, genetic variants linked to disease do not act on nearby genes along the chromosome.

4 Aug 2026

Advances in X chromosome inactivation open therapeutic opportunities for X-linked genetic disorders

A new review explores how advances in understanding X chromosome inactivation (XCI) are creating potential therapeutic opportunities for a range of X-linked genetic disorders, including Rett syndrome, Fabry disease, Duchenne muscular dystrophy, hemophilia, and others.

3 Aug 2026

RNA-based therapeutic strategy targets brain pathway behind cancer-associated cachexia

A new path has opened toward stopping cancer-associated cachexia, a devastating complication that gradually wastes patients away.

2 Aug 2026

AI-powered blood test detects liver cancer across distinct populations

Researchers at the Johns Hopkins Kimmel Cancer Center validated an artificial intelligence (AI)-powered blood test that accurately detected liver cancer in people from two geographically and biologically distinct populations and also uncovered the underlying biological signals that make the test effective.

31 Jul 2026

Blocking xenophagocytosis improves donor cell survival and interspecies organ generation

Xenophagocytosis is a natural immune process that limits interspecies organ generation by eliminating living donor cells, report researchers at Institute of Science Tokyo, Japan.

31 Jul 2026

New discovery advances sustainable production of plant-based medicines

Two plants that cause neurotoxicity and paralysis in the tiniest doses are also known to counter pain, malaria, cancer and pests.

31 Jul 2026

Scientists map protective cell networks hiding dormant breast tumor cells

Researchers at the MRC Laboratory of Medical Sciences (LMS), Imperial College London and UCL Genetics Institute have created a detailed map of cells within breast tumors and identified distinct neighborhoods of proliferating and dormant cells.

31 Jul 2026

New OpenABE gene editor improves editing efficiency by up to 36 times

A joint research team led by Professor Daesik Kim (Department of Medicine, Sungkyunkwan University), along with Professor Yong-Sub Kim (University of Ulsan College of Medicine) and Professor Jae-Hyun Park (Sungkyunkwan University School of Medicine), has announced the development of 'OpenABE' (Open Adenine Base Editor).

30 Jul 2026