Therapeutics News and Research

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Midbody remnant found to play role in cancer spread

Once thought to be the trash can of the cell, a little bubble of cellular stuff called the midbody remnant is actually packing working genetic material with the power to change the fate of other cells - including turning them into cancer.

9 Oct 2023

Advanced neuroimaging reveals surprising link between glaucoma and Alzheimer's disease

The overlap in clinical and magnetic resonance imaging (MRI) findings between Alzheimer's disease and glaucoma.

9 Oct 2023

Researchers explore immunomodulating targets for improving glioblastoma therapies

Researchers have delved into the intricate heterogeneity of glioblastoma, a notoriously aggressive brain tumor, using advanced single-cell RNA sequencing and innovative zebrafish avatars. Their findings spotlighted the LGALS1 gene's role in immunosuppression and suggested potential therapeutic avenues for personalized GBM treatment.

8 Oct 2023

Researchers develop innovative treatment option for therapy-resistant epilepsy

Neuroscientist Professor Sonja Bröer from Freie Universität Berlin is involved in the development of an innovative treatment option for therapy-resistant epilepsy.

6 Oct 2023

Study discovers protective genetic mutation for kidney disease

African Americans have long been known to be at increased risk of kidney disease due to a dangerous genetic mutation that creates a hole in the kidney cells, but Vanderbilt University Medical Center (VUMC) researchers have now discovered a protective genetic mutation that covers the hole to eliminate the risk.

6 Oct 2023

BIOVECTRA signs service agreement with Acuitas Therapeutics for unique lipid nanoparticle (LNP) delivery system used in manufacturing mRNA-based therapies

BIOVECTRA and Acuitas Therapeutics, Inc. today announced that they have entered into a technology transfer service.

From BIOVECTRA 6 Oct 2023

New antibody shows promise in reducing tau proteins associated with Alzheimer's disease

A team led by researchers from Mass General Brigham reports promising results for a monoclonal antibody that takes aim at a new target for Alzheimer's disease.

5 Oct 2023

Researchers identify new potential treatments for children with rare genetic conditions of blood vessels

A research team at the Francis Crick Institute and Great Ormond Street Hospital (GOSH)/UCL Great Ormond Street Institute of Child Health have identified new potential treatments for children with rare genetic conditions of blood vessels, which cause severe, lifelong, and disabling symptoms like seizures and impaired development.

5 Oct 2023

Researchers spearhead a new method to hone in on new cancer drug targets

Searching for new ways to block the growth of cancer cells is like looking for a needle in a haystack. Tumor cells rely on thousands of proteins to function, but only a few of those proteins can be precisely targeted by drugs to treat cancer safely and effectively.

5 Oct 2023

Blood test for pan-cancer biomarker could revolutionize early cancer detection

Diagnostic tools for timely, accurate and inexpensive early cancer detection that can assess risk or monitor response to treatment could help patients get the care they need faster and improve existing care strategies.

5 Oct 2023

Groundbreaking research focuses on brain health monitoring, early detection of neurodegenerative diseases

Associate Professor at the University of Oulu Teemu Myllylä, a leading expert in biomedical engineering, recently discussed his team's groundbreaking work in brain health monitoring and early detection of neurodegenerative diseases at the recent 6G-enabled sustainable society event.

4 Oct 2023

New AI model predicts therapeutic targets for age-related diseases

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 18, entitled, "Biomedical generative pre-trained based transformer language model for age-related disease target discovery."

4 Oct 2023

Study highlights the patient heterogeneity in atopic dermatitis and demonstrates the promises of personalized treatment

Researchers investigated endotype-phenotype associations in atopic dermatitis (AD) beyond its general clinical severity.

4 Oct 2023

Sphere Fluidics’ Cyto-Mine system selected by FairJourney Biologics to advance cell line development workflows

Sphere Fluidics, a company developing single cell analysis systems underpinned by its patented picodroplet technology, today announced the Cyto-Mine® platform has been selected by FairJourney Biologics, a world leading end-to-end antibody partner, providing integrated services across antibody discovery, engineering, and production, to expand its cell line development capabilities.

From Fluidic Sciences and Sphere Bio 4 Oct 2023

Ubiquigent collaborates with Imperial College London on DUB probe discovery to facilitate preclinical and clinical target engagement studies

Ubiquigent Limited (Ubiquigent), a drug discovery and development company harnessing novel deubiquitinase (DUB) modulators as new therapeutics for areas of high unmet medical need, today announced it is supporting a PhD student in the Institute of Chemical Biology EPSRC Centre for Doctoral Training (CDT) in Chemical Biology, at Imperial College London.

From Ubiquigent Limited 4 Oct 2023

New meningitis vaccine safe and effective for infants in Africa

University of Maryland School of Medicine (UMSOM) researchers, as part of the Infectious Diseases Clinical Research Consortium (IDCRC), provided an interim analysis showing that the pentavalent (NmCV-5) meningitis vaccine is safe for use in 9-month-old infants in the meningitis belt of sub-Saharan Africa.

3 Oct 2023

Research opens the door for better use of people's own immune system T cells to fight cancer

Using laboratory-grown cells from humans and genetically engineered mice, scientists at Johns Hopkins Medicine say they have evidence that modifying a specific protein in immune white blood cells known as CD8+ T cells can make the cells more robust, potentially opening the door for better use of people's own immune system T cells to fight cancer.

3 Oct 2023

NIH grant to fund development of new gene therapy platform for brain diseases

A two-phase NIH grant will fund research into a new CRISPR-based gene therapy platform that will target genetic brain diseases like Angelman syndrome and H1-4 (HIST1H1E) syndrome.

3 Oct 2023

Study identifies potential drug target for lymphedema

The human lymphatic system consists of a vast network of vessels that drain protein-rich fluid in tissues and transport it to lymph nodes.

3 Oct 2023

Could seaweeds be the superfood and medicine of the future?

Researchers consolidate the diverse nutritional and medicinal benefits of seaweeds, touting their potential in food, nutraceuticals, and pharmaceuticals. The study also highlights challenges and opportunities in industrial applications, calling for more research to optimize extraction and refinement processes.

2 Oct 2023

Therapeutics News and Research

Midbody remnant found to play role in cancer spread

Advanced neuroimaging reveals surprising link between glaucoma and Alzheimer's disease

Researchers explore immunomodulating targets for improving glioblastoma therapies

Researchers develop innovative treatment option for therapy-resistant epilepsy

Study discovers protective genetic mutation for kidney disease

BIOVECTRA signs service agreement with Acuitas Therapeutics for unique lipid nanoparticle (LNP) delivery system used in manufacturing mRNA-based therapies

New antibody shows promise in reducing tau proteins associated with Alzheimer's disease

Researchers identify new potential treatments for children with rare genetic conditions of blood vessels

Researchers spearhead a new method to hone in on new cancer drug targets

Blood test for pan-cancer biomarker could revolutionize early cancer detection

Groundbreaking research focuses on brain health monitoring, early detection of neurodegenerative diseases

New AI model predicts therapeutic targets for age-related diseases

Study highlights the patient heterogeneity in atopic dermatitis and demonstrates the promises of personalized treatment

Sphere Fluidics’ Cyto-Mine system selected by FairJourney Biologics to advance cell line development workflows

Ubiquigent collaborates with Imperial College London on DUB probe discovery to facilitate preclinical and clinical target engagement studies

New meningitis vaccine safe and effective for infants in Africa

Research opens the door for better use of people's own immune system T cells to fight cancer

NIH grant to fund development of new gene therapy platform for brain diseases

Study identifies potential drug target for lymphedema

Could seaweeds be the superfood and medicine of the future?

Understanding the DNA Damage Response in Innate Immunity eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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