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Elucidating the function of BRCA2 gene offers insight into cancer development

A new study shows exactly how the gene BRCA2, linked to susceptibility to breast and ovarian cancer, functions to repair damaged DNA.

3 Apr 2023

Triglyceride cycling enables fatty acid modification

Fat molecules serve as energy storage for fat cells. They consist of three fatty acids attached to a backbone of glycerol.

3 Apr 2023

Membrane attack complex could be a potential therapeutic target to slow or prevent AMD

A study from the National Eye Institute (NEI) identified rare genetic variants that could point to one of the general mechanisms driving age-related macular degeneration (AMD), a common cause of vision loss in older adults.

3 Apr 2023

Researchers report surprising first steps that promote resistance to commonly prescribed antibiotics

Antibiotic resistance is a global health threat. In 2019 alone, an estimated 1.3 million deaths were attributed to antibiotic resistant bacterial infections worldwide.

31 Mar 2023

Developing lipid nanoparticles to carry mRNA specifically to the pancreas

Therapeutics that use mRNA - like some of the COVID-19 vaccines - have enormous potential for the prevention and treatment of many diseases.

31 Mar 2023

Researchers create a visualization of the full-length human BRCA2 protein at single molecule level

Using a self-built inverted microscope complete with laser optical tweezers to capture DNA, Yale Cancer Center and University of California Davis researchers for the first time created a visualization of the full-length human BRCA2 protein at the single molecule level.

31 Mar 2023

High consumption of common artificial sweetener lowers activation of T-cells in mice

Scientists at the Francis Crick Institute have found that high consumption of a common artificial sweetener, sucralose, lowers activation of T-cells, an important component of the immune system, in mice.

31 Mar 2023

Lipid Nanoparticles (LNPs) and DNA delivery – unlocking the future of medical research

In this interview, Kate Stumpo speaks to Michael Girgis about Lipid nano particles, and the future of the field.

From Bruker Daltonics 31 Mar 2023

New insights and emerging disease-modifying drugs for Alzheimer’s disease treatment

A recent review published in Biochemical Pharmacology summarized the ongoing research, providing insights into pathophysiology and emerging drugs for Alzheimer’s disease (AD).

31 Mar 2023

Black sea urchin extract shows promise in combating atherosclerosis

A team of Italian scientists has identified potential anti-inflammatory and vasculoprotective effects of red cell extracts of the Black Sea urchin Arbacia lixula. The study has been published in the journal Nutrients.

30 Mar 2023

Common amino acid discovery improves understanding of the biological causes of depression

A common amino acid, glycine, can deliver a "slow-down" signal to the brain, likely contributing to major depression, anxiety and other mood disorders in some people, scientists at the Wertheim UF Scripps Institute for Biomedical Innovation & Technology have found.

30 Mar 2023

Riboswitch may be the key to advance gene therapy, regenerative medicine

The Okinawa Institute of Science and Technology, in collaboration with Astellas Pharma Inc., has developed a new toolkit that uses small molecules to control the activity of a piece of synthetic RNA, and ultimately regulate gene expression.

30 Mar 2023

Pulsating blood vessels drive brain waste clearance during sleep

The word "brainwashing" usually triggers negative associations. But our brain health for sure depends on it. Scientists at the University of Oslo have recently made new and important discoveries about how and why this happens when we are sleeping.

30 Mar 2023

AI outperforms the leading tools in predicting enzyme function

A new artificial intelligence tool can predict the functions of enzymes based on their amino acid sequences, even when the enzymes are unstudied or poorly understood.

30 Mar 2023

Study indicates interleukin-6-dependant pathway dysregulation as a key druggable feature of COVID-19

Researchers identified an interleukin 6 dependent alternative pathway as a therapeutic strategy against coronavirus disease 2019.

30 Mar 2023

Study paves the way for wider applications of cell reprogramming in medicine

Sanford Burnham Prebys researchers have identified a group of proteins that could be the secret to cellular reprogramming, an emerging approach in regenerative medicine in which scientists transform cells to repair damaged or injured body tissues.

29 Mar 2023

Study investigates how loss of angulin-1/LSR affects the malignancy of lung adenocarcinoma

A new research paper was published in Oncotarget's Volume 14 on March 24, 2023, entitled, "Downregulation of angulin-1/LSR induces malignancy via upregulation of EGF-dependent claudin-2 and TGF-β-dependent cell metabolism in human lung adenocarcinoma A549 cells."

29 Mar 2023

Drugs to activate STING could help prevent cancer metastasis

A team of scientists at the Sloan Kettering Institute have identified the STING cellular signaling pathway as a key player in keeping dormant cancer cells from progressing into aggressive tumors months, or even years, after they've escaped from a primary tumor.

29 Mar 2023

Study offers a novel therapeutic option to combat antibiotic-resistant pneumonia

Increases in multidrug-resistance in the bacteria Streptococcus pneumoniae have made it the fourth-leading cause of death associated with antibiotic resistance.

29 Mar 2023

Advancements and challenges of constructing artificial mitochondria and chloroplasts

Energy production in nature is the responsibility of chloroplasts and mitochondria and is crucial for fabricating sustainable, synthetic cells in the lab.

28 Mar 2023

Molecule News and Research

Elucidating the function of BRCA2 gene offers insight into cancer development

Triglyceride cycling enables fatty acid modification

Membrane attack complex could be a potential therapeutic target to slow or prevent AMD

Researchers report surprising first steps that promote resistance to commonly prescribed antibiotics

Developing lipid nanoparticles to carry mRNA specifically to the pancreas

Researchers create a visualization of the full-length human BRCA2 protein at single molecule level

High consumption of common artificial sweetener lowers activation of T-cells in mice

Lipid Nanoparticles (LNPs) and DNA delivery – unlocking the future of medical research

New insights and emerging disease-modifying drugs for Alzheimer’s disease treatment

Black sea urchin extract shows promise in combating atherosclerosis

Common amino acid discovery improves understanding of the biological causes of depression

Riboswitch may be the key to advance gene therapy, regenerative medicine

Pulsating blood vessels drive brain waste clearance during sleep

AI outperforms the leading tools in predicting enzyme function

Study indicates interleukin-6-dependant pathway dysregulation as a key druggable feature of COVID-19

Study paves the way for wider applications of cell reprogramming in medicine

Study investigates how loss of angulin-1/LSR affects the malignancy of lung adenocarcinoma

Drugs to activate STING could help prevent cancer metastasis

Study offers a novel therapeutic option to combat antibiotic-resistant pneumonia

Advancements and challenges of constructing artificial mitochondria and chloroplasts

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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