Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

AI model predicts postoperative recurrence of Crohn disease with high accuracy

Using an artificial intelligence (AI) tool that emulates how humans visualize and is trained to recognize and classify images, investigators constructed a model that predicts the postoperative recurrence of Crohn disease with high accuracy by evaluating histological images.

10 May 2022

Rural California hatches plan for engineered mosquitoes to battle stealthy predator

Bryan Ruiz moved his family into a newly built home in this Central Valley farming center seven months ago and almost immediately found they were under assault.

10 May 2022

Researchers report widespread prevalence of reactive and acute inflammatory CNS microvasculopathy in 36 COVID-19 brain autopsies

A new study has focused on the microcirculatory factors associated with neurological complications of COVID-19.

10 May 2022

Complimentary tests to quantify cognitive changes in dogs could aid humans with Alzheimer's disease

Researchers have found that a suite of complimentary tests can quantify changes in dogs suspected of suffering from cognitive decline.

9 May 2022

Researchers make breakthrough in overcoming drug resistance in a rare, devastating blood cancer

South Australian scientists have made a significant breakthrough in overcoming drug resistance in acute myeloid leukemia (AML), a rare and devastating blood cancer that kills most patients within a few years.

9 May 2022

Study investigates the cause of lymphopenia as seen in COVID-19 patients

Researchers explored the underlying mechanism resulting in thymic atrophy and subsequent lymphopenia in COVID-19 patients.

9 May 2022

The potential impact of oral vaccination against COVID-19 on transmission to naïve individuals studied in a hamster infection model

A recent article published in Science Translational Medicine demonstrated that mucosally delivered adenovirus type 5 (Ad5)-based COVID-19 vaccination minimized COVID-19 transmission and severity.

9 May 2022

New tool can help researchers interpret the clinical significance of somatic mutations in cancer

Researchers at Children's Hospital of Philadelphia have developed a new tool to help researchers interpret the clinical significance of somatic mutations in cancer.

6 May 2022

New technique can accurately detect viruses in tumors from clinical next-generation sequencing

Researchers have developed a method to accurately detect viruses from clinical next-generation sequencing and describe novel associations between specific tumors and viruses that warrant further investigation.

5 May 2022

Study finds brain circuit controlling drug withdrawal-induced anxiety and reinstatement

New research from the University of California, Irvine, finds that drug withdrawal-induced anxiety and reinstatement of drug seeking behaviors are controlled by a single pathway in the brain and centered around dopamine cells.

4 May 2022

Elevated levels of PHGDH enzyme associated with Alzheimer’s disease pathology

Elevated levels of an enzyme called PHGDH in the blood of older adults could be an early warning sign of Alzheimer's disease, and a study led by the University of California San Diego provides new evidence to support this claim.

4 May 2022

Study offers a path to closing the knowledge gap about differences in breast cancer genes

Too many women are getting unnecessary mastectomies and other invasive procedures because of a knowledge gap about differences in cancer genes. A new study offers a path to closing the gap.

4 May 2022

Research shows how Alzheimer's disease affects the functional architecture of the brain

A new study led by investigators at Massachusetts General Hospital (MGH) shows the impact of early amyloid-β and tau protein accumulation on disrupting connections between brain structures that are important for memory.

3 May 2022

Researchers discover how Acinetobacter baumannii can survive on hospital surfaces without water

The pathogen Acinetobacter baumannii can survive on hospital surfaces - without water - for months, an ability that has helped it become a leading cause of hospital-acquired infections.

2 May 2022

The generation of SARS-CoV-2 virus-like particles in insect cells

Researchers have reported the development of a promising COVID-19 vaccine candidate which is based on SARS-CoV-2 VLPs, derived from the co-expression of the spike, membrane, and envelope structural proteins in the baculovirus expression system.

2 May 2022

Scientists gain important insights into novel mutation behind synucleinopathies

Parkinson's disease and Lewy body dementia belong to a family of neurodegenerative disorders called synucleinopathies because they are caused by the pathological accumulation of protein alpha-synuclein into structures called Lewy bodies and Lewy neurites in the brain.

29 Apr 2022

Specific genes that play important role in schizophrenia identified

Identification of a SARS-CoV-2 neutralizing human monoclonal antibody with a remarkable broad-spectrum neutralization and protection efficacy

Researchers identified a human monoclonal antibody (mAb), 87G7, with in vitro neutralizing activity against several SARS-CoV-2 VOCs, including Alpha, Beta, Gamma, Delta, and Omicron.

28 Apr 2022

Pathology News and Research

Further Reading

AI model predicts postoperative recurrence of Crohn disease with high accuracy

Rural California hatches plan for engineered mosquitoes to battle stealthy predator

Researchers report widespread prevalence of reactive and acute inflammatory CNS microvasculopathy in 36 COVID-19 brain autopsies

Complimentary tests to quantify cognitive changes in dogs could aid humans with Alzheimer's disease

Researchers make breakthrough in overcoming drug resistance in a rare, devastating blood cancer

Study investigates the cause of lymphopenia as seen in COVID-19 patients

The potential impact of oral vaccination against COVID-19 on transmission to naïve individuals studied in a hamster infection model

New tool can help researchers interpret the clinical significance of somatic mutations in cancer

New technique can accurately detect viruses in tumors from clinical next-generation sequencing

Study finds brain circuit controlling drug withdrawal-induced anxiety and reinstatement

Elevated levels of PHGDH enzyme associated with Alzheimer’s disease pathology

Study offers a path to closing the knowledge gap about differences in breast cancer genes

Research shows how Alzheimer's disease affects the functional architecture of the brain

Researchers discover how Acinetobacter baumannii can survive on hospital surfaces without water

The generation of SARS-CoV-2 virus-like particles in insect cells

Scientists gain important insights into novel mutation behind synucleinopathies

Specific genes that play important role in schizophrenia identified

Yale researchers identify immune system culprit in severe COVID cases

Tufts scientists discover a previously unknown function performed by astrocytes

Identification of a SARS-CoV-2 neutralizing human monoclonal antibody with a remarkable broad-spectrum neutralization and protection efficacy

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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