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Researchers deplete key protein for DNA replication using protein degradation system

Researchers from Tokyo Metropolitan University and the FIRC Institute of Molecular Oncology in Italy have succeeded in depleting AND-1, a key protein for DNA replication, by using a recently developed conditional protein degradation system.

29 Sep 2018

Verastem Oncology selects US Bioservices to dispense COPIKTRA capsules

US Bioservices, a specialty pharmacy that is a part of AmerisourceBergen, today announced that it has been selected by Verastem OncologyTM to dispense COPIKTRA (duvelisib) capsules.

28 Sep 2018

RTI Surgical showcases innovative spine portfolio at NASS 2018

RTI Surgical, Inc., a global surgical implant company, will showcase research reinforcing the strength of its spine portfolio, notably the Fortilink IBF series featuring TETRAfuse 3D Technology, at the North American Spine Society's 33rd Annual Meeting in Los Angeles, September 26-29.

26 Sep 2018

Logos Biosystems Introduces the New CELENA X High Content Imaging System

Logos Biosystems has released the all-new CELENA® X integrated High Content Imaging System, providing the complete solution for rapid high content image acquisition and quantitative analysis.

From Logos Biosystems 20 Sep 2018

Study reveals new therapeutic target for pediatric tumor-associated intractable epilepsy

Pediatric brain tumors are characterized by frequent complications due to intractable epilepsy compared to adult brain tumors. However, the genetic cause of refractory epilepsy in pediatric brain tumors has not been elucidated yet, and it is difficult to treat patients because the tumors do not respond to existing antiepileptic drugs and debilitate children's development.

19 Sep 2018

Researchers describe cell mechanism that optimizes proteins production in stressful situations

The different genes within the genome must be expressed in precise levels and in the exact moment if the complex balance regulating cell activity is to be maintained.

19 Sep 2018

Vitamin D may reduce breast cancer mortality in women with lower BMI

Vitamin D is already well known for its benefits in building healthy bones. A new study supports the idea that it also may reduce cancer risk as well as breast cancer mortality, especially in women with a lower body mass index.

19 Sep 2018

Researchers use CRISPR screen to reveal new targets in squamous cell carcinomas

A little p63 goes a long way in embryonic development - and flaws in p63 can result in birth defects like cleft palette, fused fingers or even missing limbs.

18 Sep 2018

New program combines basic science and social benefits to address HIV risk among young women

A program established by investigators from the Ragon Institute of Massachusetts General Hospital, MIT and Harvard is addressing the persistently elevated risk of HIV infection among young women in South Africa from two angles - first, investigating biological factors that modulate infection risk along with the early immunologic events following viral exposure, and second, alleviating the socioeconomic factors that limit opportunities for young women, the group at greatest risk of infection in the region of the world hardest hit by the HIV epidemic.

17 Sep 2018

Investigators pinpoint exact stage of retinoblastoma development in children

Investigators at Children's Hospital Los Angeles have been able to pinpoint the exact stage of development of the human retina, when cells can grow out of control and form cancer-like masses.

14 Sep 2018

Case Western Reserve professor wins $2 million grant to study colorectal cancer

Lan Zhou, MD, PhD, associate professor of pathology at Case Western Reserve University School of Medicine, has received a five-year, $2 million grant from the National Cancer Institute of the National Institutes of Health to study human colorectal cancer.

14 Sep 2018

MAPK pathway mediates normal kidney development, reveals study

The prevalence of kidney diseases is growing rapidly due to an aging population and an increased incidence of diseases like diabetes.

14 Sep 2018

New research sheds light on the causes of diabetes

The main cause of all forms of diabetes is pancreatic beta-cell dysfunction. Beta cells, found in the pancreatic islets, store and release insulin.

14 Sep 2018

Blood serum induces spontaneous movement and growth of skin cells

What happens to skin cells when they are confronted with blood? A team of researchers from Oslo University Hospital, led by Emma Lång and Stig Ove Bøe, performed experiments on blood-deprived cells that were subsequently exposed to blood serum.

13 Sep 2018

Aging may have originated at the very beginning of life, says study

A new USC Dornsife study indicates that aging may have originated at the very beginning of the evolution of life, at the same time as the evolution of the first genes.

13 Sep 2018

How 'bad' bacteria gain an upper hand in the human gut

A study has revealed that the bacterium C. difficile gains a competitive advantage over protective bacteria in the human gut by producing para-cresol.

11 Sep 2018

Gene involved in circadian rhythms can be potential target for glioblastoma treatment

Scientists with the Virginia Tech Carilion Research Institute say a gene involved in the body's circadian rhythms is a potential target for therapies to help patients with a deadly form of brain cancer known as glioblastoma.

11 Sep 2018

Study: Better infrastructure and governance associated with lower measures of antimicrobial resistance

An international team of researchers from CDDEP, Australian National University and Cardiff University and the Monarch Institute has published a new study showing that the proliferation of disease-causing antibiotic resistant organisms is correlated with many social and environmental factors such as poor sanitation, unsafe water and higher incomes.

7 Sep 2018

Researchers reveal how rapidly spreading ovarian cancer cells take the next steps

In nearly 80 percent of women with ovarian cancer, the disease has already spread to the omentum before it was diagnosed. Within the omentum - a large, energy-dense fat pad that covers the intestines - the cancer grows even faster.

7 Sep 2018

Verastem doses first patient in Phase I/II clinical trial of duvelisib in combination with venetoclax

Verastem, Inc., operating as Verastem Oncology, a biopharmaceutical company focused on developing and commercializing medicines to improve the survival and quality of life of cancer patients, today announced dosing of the first patient in a multicenter Phase I/II clinical trial at the Dana-Farber/Harvard Cancer Center of duvelisib in combination with venetoclax in patients with relapsed or refractory chronic lymphocytic leukemia or small lymphocytic lymphoma.

6 Sep 2018

Proliferation News and Research

Researchers deplete key protein for DNA replication using protein degradation system

Verastem Oncology selects US Bioservices to dispense COPIKTRA capsules

RTI Surgical showcases innovative spine portfolio at NASS 2018

Logos Biosystems Introduces the New CELENA X High Content Imaging System

Study reveals new therapeutic target for pediatric tumor-associated intractable epilepsy

Researchers describe cell mechanism that optimizes proteins production in stressful situations

Vitamin D may reduce breast cancer mortality in women with lower BMI

Researchers use CRISPR screen to reveal new targets in squamous cell carcinomas

New program combines basic science and social benefits to address HIV risk among young women

Investigators pinpoint exact stage of retinoblastoma development in children

Case Western Reserve professor wins $2 million grant to study colorectal cancer

MAPK pathway mediates normal kidney development, reveals study

New research sheds light on the causes of diabetes

Blood serum induces spontaneous movement and growth of skin cells

Aging may have originated at the very beginning of life, says study

How 'bad' bacteria gain an upper hand in the human gut

Gene involved in circadian rhythms can be potential target for glioblastoma treatment

Study: Better infrastructure and governance associated with lower measures of antimicrobial resistance

Researchers reveal how rapidly spreading ovarian cancer cells take the next steps

Verastem doses first patient in Phase I/II clinical trial of duvelisib in combination with venetoclax

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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