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The human brain is the center of the human nervous system and is a highly complex organ. Enclosed in the cranium, it has the same general structure as the brains of other mammals, but is over three times as large as the brain of a typical mammal with an equivalent body size.

New anti-cocaine monoclonal antibody moves forward towards clinical studies in humans

A University of Cincinnati researcher who has developed an immunotherapy to help reverse cocaine addiction that's been successful in animal models says he hopes to have it in clinical trials in human volunteers within a year.

28 Feb 2017

New molecule may inhibit growth of aggressive pediatric brain tumor

Northwestern Medicine scientists have found a molecule that stops the growth of an aggressive pediatric brain tumor. The tumor is always fatal and primarily strikes children under 10 years old.

27 Feb 2017

Scientists gain new insight into early brain pathology of schizophrenia using adult skin cells

The skin cells of four adults with schizophrenia have provided an unprecedented "window" into how the disease began while they were still in the womb, according to a recent paper in Schizophrenia Research.

27 Feb 2017

$Study finds ketogenic diet as 'feasible' option for people with super-refractory status epilepticus$

Study finds ketogenic diet as 'feasible' option for people with super-refractory status epilepticus

In a small phase I and II clinical trial, Johns Hopkins researchers and colleagues elsewhere found that the high-fat, low-carbohydrate ketogenic diet was a safe and effective treatment option for the majority of adults experiencing a relatively rare, often fatal and always severe form of epilepsy marked by prolonged seizures that require medically induced comas to prevent them from further damaging the body and the brain.

27 Feb 2017

Researchers identify genetic variants that may contribute to schizophrenia

New research has identified sections of DNA associated with altered regulation of gene expression underlying schizophrenia.

27 Feb 2017

New wearable brain-imaging device measures how brains sync up when humans interact

Great ideas so often get lost in translation -- from the math teacher who can't get through to his students, to a stand-up comedian who bombs during an open mic night.

27 Feb 2017

Hypoxia may be cause for seizure-related neuronal degeneration in epilepsy, study finds

Neuronal degeneration is the most severe long-term consequence of repetitive seizures in patients with epilepsy, which until now was thought to be primarily caused by excitotoxicity, or over-stimulation of the neurons.

27 Feb 2017

Study finds new mechanism underlying epileptic seizures

Prolonged epileptic seizures may cause serious problems that will continue for the rest of a patient's life. As a result of a seizure, neural connections of the brain may be rewired in an incorrect way.

27 Feb 2017

GUMC launches phase II clinical study to examine safety of cancer drug for Parkinson's disease

Georgetown University Medical Center today announces the launch of a phase II clinical trial to study the safety of the cancer drug nilotinib and its effects on clinical outcomes and biomarkers in people with Parkinson's disease.

27 Feb 2017

Living with children linked to insufficient sleep among women, study finds

New research backs up what many women already know: They're sleep deprived. Unlike men, a good night's sleep for women is affected by having children in the house, according to a preliminary study released today that will be presented at the American Academy of Neurology's 69th Annual Meeting in Boston, April 22 to 28, 2017.

27 Feb 2017

Study finding suggests new ways in which genetic mutations may cause brain disorders

Many kids say they love their mom and dad equally, but there are times when even the best prefers one parent over the other. The same can be said for how the body's cells treat our DNA instructions. It has long been thought that each copy - one inherited from mom and one from dad - is treated the same. A new study from scientists at the University of Utah School of Medicine shows that it is not uncommon for cells in the brain to preferentially activate one copy over the other.

25 Feb 2017

Researchers shed new light on molecular pump that ejects anticancer agents

Sometimes cells resist medication by spitting it back out. Cancer cells, in particular, have a reputation for defiantly expelling the chemotherapy drugs meant to kill them. Researchers at The Rockefeller University have shed new light on a molecular pump that makes this possible, by determining its three-dimensional structure, down to the level of atoms.

25 Feb 2017

Deep brain stimulation may help improve mental, physical health in patients with anorexia nervosa

Deep brain stimulation might alter the brain circuits that drive anorexia nervosa symptoms and help improve patients’ mental and physical health, according to a small study published in The Lancet Psychiatry.

25 Feb 2017

New study confirms benefits of Medtronic’s Solitaire stent retriever for stroke patients in real-world setting

Data presented today on Medtronic’s Solitaire stent retriever at the International Stroke Conference in Houston demonstrate that the results from the four pivotal randomized controlled trials – SOLITAIRE FR With the Intention For Thrombectomy as PRIMary Endovascular Treatment for Acute Ischemic Stroke, Endovascular Treatment for Small Core and Proximal Occlusion Ischemic Stroke, EXtending the Time for Thrombolysis in Emergency Neurological Deficits - Intra-Arterial and Endovascular Revascularization With Solitaire Device Versus Best Medical Therapy in Anterior Circulation Stroke Within 8 Hours – can be replicated in U.S. centers, in a pragmatic, real-world setting reconfirming the benefits of mechanical thrombectomy in patients suffering acute ischemic stroke (AIS).

25 Feb 2017

MGH researchers discover regulators of gene expression programs in medulloblastoma

Massachusetts General Hospital researchers have identified a mechanism that controls the expression of genes regulating the growth of the most aggressive form of medulloblastoma, the most common pediatric brain tumor. In their report published online in Cancer Discovery, the team also identifies potential targets for future treatments.

24 Feb 2017

Pitt study sheds light on shared roots of schizophrenia and rheumatoid arthritis

An in-depth computational analysis of genetic variants implicated in both schizophrenia and rheumatoid arthritis by researchers at the University of Pittsburgh points to eight genes that may explain why susceptibility to one of the disorders could place individuals at lower risk for the other, according to the results of a study published today in the journal npj Schizophrenia.

24 Feb 2017

Brain News and Research

Further Reading

New anti-cocaine monoclonal antibody moves forward towards clinical studies in humans

New molecule may inhibit growth of aggressive pediatric brain tumor

Scientists gain new insight into early brain pathology of schizophrenia using adult skin cells

Study finds ketogenic diet as 'feasible' option for people with super-refractory status epilepticus

Researchers identify genetic variants that may contribute to schizophrenia

New wearable brain-imaging device measures how brains sync up when humans interact

Hypoxia may be cause for seizure-related neuronal degeneration in epilepsy, study finds

Study finds new mechanism underlying epileptic seizures

GUMC launches phase II clinical study to examine safety of cancer drug for Parkinson's disease

Living with children linked to insufficient sleep among women, study finds

Study finding suggests new ways in which genetic mutations may cause brain disorders

Researchers shed new light on molecular pump that ejects anticancer agents

Deep brain stimulation may help improve mental, physical health in patients with anorexia nervosa

New study confirms benefits of Medtronic’s Solitaire stent retriever for stroke patients in real-world setting

MGH researchers discover regulators of gene expression programs in medulloblastoma

Pitt study sheds light on shared roots of schizophrenia and rheumatoid arthritis

Dietary prebiotics can improve sleep after stress exposure, study suggests

Princeton-Intel collaboration builds new software to decode brain scans

New humanized model enables better characterization of Alzheimer's pathology

Newly discovered gene variants increase risk of anxiety disorders

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

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Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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