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Phase III trials indicate reversible cognitive side effects in brain metastases treatment

A substantial number of patients with brain metastases who experience cognitive side effects following radiation therapy may fully regain cognitive function, according to a pooled analysis of three large, phase III clinical trials.

29 Sep 2024

Extending survival in meningioma patients with innovative radiopharmaceutical therapy

A radiopharmaceutical therapy that has successfully extended progression-free survival for patients with neuroendocrine tumors shows early promise for delivering similar benefits to patients with difficult-to-treat meningioma, a type of brain tumor.

29 Sep 2024

Brusatol may serve as potential adjuvant therapy for pancreatic ductal adenocarcinoma

Announcing a new publication for Acta Materia Medica journal. Chemoresistance to gemcitabine (Gem) remains a substantial obstacle in the treatment of pancreatic ductal adenocarcinoma carcinoma (PDAC).

29 Sep 2024

Diet and gut dysbiosis linked to rheumatoid arthritis

Review highlights how gut dysbiosis and dietary factors are linked to rheumatoid arthritis, influencing disease progression and inflammation. Researchers explore how specific diets may help modulate the gut microbiome to improve symptoms.

29 Sep 2024

From patient to physician: EJ Beck's medical journey at NYU Langone Health

As a child, EJ Beck was treated for a rare pediatric thyroid cancer at NYU Langone Health. About 10 years after the scan that declared her cancer-free, Beck was accepted into her No. 1 choice for a medical school: NYU Grossman School of Medicine.

27 Sep 2024

UCLA Health researchers showcase advances in radiation oncology at ASTRO

UCLA Health Jonsson Comprehensive Cancer Center researchers and physicians who specialize in treating patients with radiation therapies will present data on the latest radiation oncology research and clinical trial results at the 66th annual American Society for Radiation Oncology (ASTRO) meeting in Washington D.C., Sept. 29 to Oct. 2.

27 Sep 2024

Estrogen found to promote tumor growth in breast cancers without receptors

Estrogens are known to drive tumor growth in breast cancer cells that carry its receptors, but a new study by Duke Cancer Institute researchers unexpectedly finds that estrogens play a role in fueling the growth of breast cancers without the receptors, as well as numerous other cancers.

27 Sep 2024

Novel approach combines glutaminase and HuR blockade to suppress breast cancer growth

A study led by Brazilian researchers and reported in an article published in the journal Nature Communications proposes that simultaneously targeting the enzyme glutaminase and the protein HuR, both of which are essential to tumor progression, may be effective in treating breast cancer.

27 Sep 2024

Study offers new insight into the link between oral microbiome and head and neck cancers

More than a dozen bacterial species among the hundreds that live in people's mouths have been linked to a collective 50% increased chance of developing head and neck squamous cell carcinoma (HNSCC), a new study shows.

26 Sep 2024

Study reveals positive correlation between type 2 immunity and long-term cancer remission

Results from a preclinical study in mice, led by EPFL, and a collaborative clinical study in patients show that the type 2 immune response – associated with parasitic infection and thought to play a negative role in cancer immunity – is positively correlated with long-term cancer remission.

26 Sep 2024

Innovative CAR-T cells effectively target glioblastoma with reduced toxicity

Glioblastoma is the most common and most aggressive primary brain tumor, with an average survival after diagnosis of less than two years, and against which current treatments remain ineffective.

26 Sep 2024

Targeting tumor immunity with transferrin receptor-directed photodynamic therapy

This new article publication from Acta Pharmaceutica Sinica B, discusses a transferrin receptor-targeted immunostimulant for photodynamic immunotherapy against metastatic tumors through β-catenin/CREB interruption.

26 Sep 2024

Barcoding technology reveals secrets of cancer metastasis

Metastatic cancer can be a devastating diagnosis. The cancer is spreading. It may travel to multiple organs in the body. This could mean more pain and ultimately, death.

26 Sep 2024

Multi-omics analysis reveals mechanism of action for ruthenium-based anti-cancer agent

This study is led by Prof. Cai-Ping Tan, Prof. Zong-Wan Mao (MOE Key Laboratory of Bioinorganic and Synthetic Chemistry, School of Chemistry, Sun Yat-Sen University) and Prof. Zheng-Qiu Li (School of Pharmacy, MOE Key Laboratory of Tumor Molecular Biology, Jinan University).

26 Sep 2024