Hormones News and Research

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Targeted uterine mRNA treatment boosts fertility outcomes in mice

Researchers from the Wilmer Eye Institute, Johns Hopkins Medicine Center for Nanomedicine - which designs nanotechnology-based platforms for clinical translation across specialties - developed a strategy for delivering therapeutic messenger RNA (mRNA) to the inner lining of the uterus (endometrium) in mice via modified lipid nanoparticles (LNPs), which are small capsules made of fatty molecules.

22 Jan 2026

Blood lipid–hormone ratios predict future asthma attacks years in advance

This study shows that specific ratios of circulating sphingolipids to steroids can predict the risk of future asthma exacerbations over five years with high discriminatory performance. By integrating metabolomics with longitudinal medical records, the research highlights lipid–hormone pathway imbalance as a key driver of asthma instability.

20 Jan 2026

Ashwagandha aids recovery without blunting training stress in athletes

Six weeks of Ashwagandha root extract supplementation in semi-professional team-sport athletes was associated with sex-specific effects during pre-season training. Females showed improved perceived recovery with stable cortisol, while males demonstrated gains in lower-body power with stable cortisone levels.

18 Jan 2026

Thermogenic beige fat protects blood vessels from hypertension

Obesity causes hypertension. Hypertension causes cardiovascular disease. And cardiovascular disease is the leading cause of death worldwide.

15 Jan 2026

Endocrine-disrupting chemicals and adverse life events during pregnancy affect children's development

Research at Karlstad University shows that exposure to endocrine-disrupting chemicals and adverse life events during pregnancy can influence children's behavior and brain development.

14 Jan 2026

Breastfeeding is linked to lower depression and anxiety years later

A decade-long study links breastfeeding to lower anxiety and depression in mothers, suggesting long-term mental health benefits beyond the postnatal period.

13 Jan 2026

Fish study reveals how ovulation triggers sexual receptivity in females

A research team led by Hiroshima University and Tokyo University of Agriculture and Technology have proposed a neuroendocrine mechanism in bony fish that signals ovulation from the ovaries to the brain, using the medaka fish as a model; the first step to elucidate the neural circuits for facilitation of sexual receptivity in female teleosts.

9 Jan 2026

The gut is not just digestive and new evidence shows it actively controls brain function

This comprehensive review synthesizes a decade of human and animal research to explain how the gut and brain communicate through hormonal, neural, immune, and microbial pathways. It highlights how disruptions in these pathways contribute to gastrointestinal, metabolic, and neurological disorders, and how modern therapies are beginning to exploit gut–brain signaling for clinical benefit.

6 Jan 2026

Can ketogenic diets help PCOS? New analysis points to weight and insulin gains

A systematic review and meta-analysis of 15 studies found that ketogenic diets were associated with short-term reductions in body weight, waist circumference, insulin resistance, and some reproductive hormones in women with polycystic ovary syndrome, primarily among those with overweight or obesity. However, substantial heterogeneity, low certainty of evidence, limited safety reporting, and short follow-up periods mean the clinical effectiveness and long-term sustainability of ketogenic diets in PCOS remain uncertain.

5 Jan 2026

Weaker and fragmented circadian rhythms linked to higher dementia risk

Circadian rhythms that are weaker and more fragmented are linked to an increased risk of dementia, according to a new study published on December 29, 2025, in Neurology®, the medical journal of the American Academy of Neurology.

4 Jan 2026

DNA twisting controls how cells respond to estrogen

Estrogens, the main female sex hormone, although they also perform some functions in men, are involved in a myriad of processes, which is why the body changes so much during menopause. This is because estrogens regulate hundreds of genes.

19 Dec 2025

ACE2 protein may play a protective role against high blood pressure and type 2 diabetes

A collaborative study from the MRC Laboratory of Medical Sciences (LMS) and Imperial College London has found that the protein ACE2 may play a protective role against two common conditions, high blood pressure and type-2 diabetes, which affect millions of people worldwide.

19 Dec 2025

Cutting carbs, not fat, may better control appetite in women

Research indicates low-carb diets may enhance appetite regulation and reduce food cues in women with lipedema, offering a dietary intervention advantage.

19 Dec 2025

Estrogen drives gut pain and explains higher rates of IBS in women

Women are dramatically more likely than men to suffer from irritable bowel syndrome (IBS), a chronic condition causing abdominal pain, bloating, and digestive discomfort.

18 Dec 2025

Injuries don’t rise during menstruation in elite women footballers

The study finds no rise in injuries during menstruation in elite football, yet highlights increased severity, urging better tracking for athlete health.

18 Dec 2025

Early embryos and the uterus engage in active communication during implantation

A new study shows that the embryo and the uterine lining conduct an active "conversation" from the very earliest stages of implantation. They engage in a back and forth of tiny packages called extracellular vesicles and lipid droplets, which carry metabolites and signals.

17 Dec 2025

How Traditional Chinese Medicine may reshape the gut microbiome to ease insulin resistance in PCOS

This review synthesizes evidence that gut microbiota dysbiosis contributes to insulin resistance and symptom severity in polycystic ovary syndrome through impaired barrier function, inflammation, and altered microbial metabolites. It evaluates how Traditional Chinese Medicine may modulate these pathways while highlighting major gaps in clinical validation, safety, and standardization.

16 Dec 2025

Injury burden is higher during menstruation in professional female footballers

The menstrual cycle is a key physiological process in women: it impacts performance, neuromuscular control, metabolism, and immune response.

16 Dec 2025

Tiny blood particles help shuttle a hormone through the body

Researchers at Touro University Nevada have discovered that tiny particles in the blood, called extracellular vesicles (EVs), are a major player in how a group of hormones are shuttled through the body. Physical exercise can stimulate this process.

15 Dec 2025

Scientists create light-controlled versions of cholesterol

High levels of cholesterol are linked to heart disease, stroke, and many other health problems. However, this complex and vital fatty, water insoluble molecule-a lipid-is found in every cell of the body and is not all bad news. It also regulates crucial processes that science has yet to map.

15 Dec 2025