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Unveiling the metabolic pathways of Fusobacterium nucleatum in OSCC

A recent study has made significant strides in uncovering how the oral microbiome, particularly the bacterium Fusobacterium nucleatum, plays a crucial role in the progression of oral squamous cell carcinoma (OSCC). By identifying key interactions between this common oral bacterium and host cells, the research has unveiled important metabolic pathways and mechanisms that may serve as potential therapeutic targets.

17 Jan 2025

Majority of naloxone recipients in NYC at high risk of overdose

The overwhelming majority of those in New York City who obtained a naloxone kit to counteract opioid overdose had a high need for the drug, according to a new study by Weill Cornell Medicine investigators and the New York City Department of Health and Mental Hygiene.

16 Jan 2025

Review highlights the pathogenesis and clinical spectrum of Nipah virus infection

Nipah virus (NiV), a zoonotic paramyxovirus with significant human health implications, has garnered considerable attention due to its high fatality rates and potential for human-to-human transmission, posing a global public health threat.

15 Jan 2025

The impact of extreme weather events on HIV prevention and care

Researchers review the impact of extreme weather events related to climate change on HIV strategies.

13 Jan 2025

Innovative tablet combination shows promise in fighting Trichuris trichiura and other helminths

A new tablet combining albendazole and ivermectin is safe and more effective than albendazole alone in treating Trichuris trichiura and other soil-transmitted helminths (STH), according to a clinical trial conducted by the STOP consortium and led by the Barcelona Institute of Global Health (ISGlobal), a centre supported by "la Caixa" Foundation.

10 Jan 2025

Household dogs found to contribute to the spread of antibiotic-resistant Salmonella

Antibiotic-resistant Salmonella is a serious public health concern that has increased in recent years as the bacteria have developed ways to survive drugs.

9 Jan 2025

Aircraft noise pollution harms arteries, but heart drugs show promise in animal model research

Alpha- and beta-blockers reduce oxidative stress and inflammation caused by aircraft noise but fail to prevent hypertension, highlighting their potential to protect vascular health in noise-exposed individuals.

9 Jan 2025

Professor Alison Elliott honored with OBE for contributions to global health

Leading clinical researcher Professor Alison Elliott has been honoured with an OBE in the King's New Year Honours for services to medicine and global health.

3 Jan 2025

Experts warn about counterfeit and illicit alcohol during the holiday season

Experts from a renowned international brewing and distilling centre are warning people to watch out for counterfeit and illicit alcohol - spirits - whether they're travelling abroad over the festive season or celebrating at home.

23 Dec 2024

New method detects human fecal contamination in water

The presence of human waste in sewage overflow or stormwater runoffs that ultimately find their way into rivers and lakes is a major public health hazard.

23 Dec 2024

New insights into respiratory syncytial virus and prevention strategies

Respiratory syncytial virus (RSV) is a major cause of respiratory infections, particularly in infants, children under 5 years, and older adults. Its rapid spread makes RSV a serious public health concern. Currently, there are no effective medications for RSV, and current treatment focuses on providing supportive care and preventing its spread.

20 Dec 2024

US cities struggle with rising number of households without running water

More American cities – even those seen as affluent – are home to people living without running water as people are being 'squeezed' by unaffordable housing and the cost-of-living crisis, new research finds.

20 Dec 2024

Reducing hand hygiene monitoring could save hospitals time and money

Hand hygiene (HH) monitoring in hospitals could be reduced significantly, allowing infection preventionists to redirect efforts toward quality improvement and patient safety initiatives, according to a new study published in the American Journal of Infection Control.

20 Dec 2024

Global study reports significant decline in diarrheal disease mortality

New global study reports a 60% drop in global mortality from diarrheal diseases, but children and the elderly still have the highest death rates, particularly in sub-Saharan Africa and South Asia.

19 Dec 2024

Radboud study links lockdowns to heightened immune reactions post-pandemic

Research from Radboud university medical center shows that the lockdowns during the COVID-19 pandemic had a significant impact on people's immune response to microorganisms.

19 Dec 2024

Women face greater barriers to accessing mobility aids despite higher need

Women are more likely than men to experience mobility limitations that could benefit from the use of mobility aids but are much less likely to use them when needed, according to a new study from researchers at UCL and the London School of Hygiene and Tropical Medicine (LSHTM).

14 Dec 2024

Herpes infections affect 846 million people worldwide

Around 846 million people aged between 15 and 49 are living with genital herpes infections – more than 1 in 5 of this age-group globally – according to new estimates released today.

11 Dec 2024

Vancouver study reveals surge in severe Shigella cases in homeless population

A recent study published in Clinical Infectious Diseases has uncovered an increase in severe multidrug-resistant (MDR) Shigella sonnei infections, particularly among people experiencing homelessness (PEH) in Vancouver, Canada.

6 Dec 2024

Disrupted sleep-wake rhythms linked to liver disease progression

The prevalence of MASLD (metabolic dysfunction-associated steatotic liver disease) is exploding in most regions of the world, boosted by increased obesity and sedentary lifestyles. MASLD (formerly known as non-alcoholic fatty liver disease) is already the most common liver disorder: it affects 30% of adults and between 7% and 14% of children and adolescents, and this prevalence is predicted to rise to more than 55% of adults by 2040.

4 Dec 2024

Disrupted sleep patterns identified in patients with metabolic dysfunction-associated steatotic liver disease

The prevalence of MASLD (metabolic dysfunction-associated steatotic liver disease) is exploding in most regions of the world, boosted by increased obesity and sedentary lifestyles.

2 Dec 2024