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Mapping the evolutionary timeline and population distribution of E. coli’s protective outer capsule

In a new study, published today (15 June) in Nature Communications, a multi-centre team led by the Wellcome Sanger Institute, the University of Oslo, Imperial College London and UCL, has mapped for the first time the evolutionary timeline and population distribution of Escherichia coli’s protective outer capsule, which is responsible for the bacterium’s virulence.

15 Jun 2023

Complete genomics announces updated mission and new partnerships on 18th anniversary

Complete Genomics, Inc., a pioneering genomics company, today unveiled updated mission/vision statement to reflect renewed ambitions in taking on more for a better world, in celebration of its 18th anniversary.

From MGI 15 Jun 2023

New method of insulin delivery lowers the risk of hypoglycemia compared to current diabetes treatments

Insulin production has, for the last 50 or so years, come with some risks to the patient. Even so, the medication is lifesaving for the estimated 537 million adults living with diabetes worldwide, with that number expected to grow.

15 Jun 2023

Understanding the developmental link: vitamin D's role in metabolic disease risk

Study showed that transplanting fetal hematopoietic stem cells exposed to vitamin D deficiency induces diabetes.

14 Jun 2023

Tracing the ancestry of hybrids using a new method

If you've ever kept a garden, you're probably familiar with hybrids, from disease-resistant tomatoes to Stargazer lilies.

13 Jun 2023

Berlin scientists further improve nasal vaccine against coronavirus

After having successfully tested a mucosal vaccine against coronavirus in animals just months ago, Berlin scientists have now further developed their live SARS-CoV-2 vaccine.

13 Jun 2023

ACMG publishes updated recommendations for CFTR carrier screening

The American College of Medical Genetics and Genomics (ACMG) has released updated recommendations for CFTR carrier screening –Updated recommendations for CFTR carrier screening: A position statement of the American College of Medical Genetics and Genomics.

13 Jun 2023

Breaking barriers: hydrogel reservoir unleashes the potential of HSV-1 virotherapy in cancer

Researchers evaluated the therapeutic efficacy of Navoximod.

13 Jun 2023

Blood culture vs. metagenomic next-generation sequencing for the detection of pathogenic microbes in patients with suspected bloodstream infections

A recent study published in Scientific Reports compared the detection of pathogenic microbes between blood culture and metagenomic next-generation sequencing in patients suspected of bloodstream infections.

13 Jun 2023

"Homing gene drive system" could help suppress agricultural pests

Researchers have developed a "homing gene drive system" based on CRISPR/Cas9 that could be used to suppress populations of Drosophila suzukii vinegar flies – so-called "spotted-wing Drosophila" that devastate soft-skinned fruit in North America, Europe and parts of South America – according to new research from North Carolina State University.

12 Jun 2023

Scientists find clues to how we maintain constant blood sugar levels after meals

Scientists from the Berlin Institute of Health at Charité (BIH), along with colleagues from the United Kingdom, have found clues as to how we maintain constant blood sugar levels after we have eaten.

12 Jun 2023

Study offers novel insights into the evolution of multiple myeloma

A new study by researchers at The University of Texas MD Anderson Cancer Center highlights novel insights into the evolution of multiple myeloma from precursor disease, which may help better identify patients likely to progress and develop new interventions.

12 Jun 2023

Study unveils potential early detection algorithm for neurodegeneration in rare genetic disorder

Xeroderma pigmentosum (XP) is a rare and devastating genetic disorder characterised by an inability to repair skin damage caused by ultraviolet (UV) light.

11 Jun 2023

Common genetic factors could be used to identify individuals at high risk of developing colorectal cancer

Rates of colorectal cancer are high despite widespread adoption of screening programs in many high-income European countries.

11 Jun 2023

Scientists use machine learning to unveil new predictors of post-menopausal breast cancer

Researchers identify five novel correlations with post-menopausal breast cancer including urine biomarkers, blood counts, and blood biochemistry.

11 Jun 2023

AI system in eye scans enables better diagnosis of inherited retinal diseases

Inherited retinal diseases (IRDs), single-gene disorders affecting the retina, are very difficult to diagnose since they are uncommon and involve changes in one of many candidate genes.

9 Jun 2023

ABCC9 gene variants influence the pitch of voices

In a paper published today in Science Advances, an international team led by deCODE genetics, a subsidiary of Amgen, reveals the discovery of sequence variants in the gene ABCC9 that influence the pitch of voices.

9 Jun 2023

The BABY1000 study: chasing lifetime risk factors in prenatal and early postnatal life

Preconceptional parental health, pregnancy health, and early infant environment and health.

9 Jun 2023

Study may help advance data on oncolytic adenovirus mediated double suicide-gene therapy for high-grade brain tumors

Researchers in the Hermelin Brain Tumor Center at Henry Ford Health are leading a Phase I clinical trial studying the maximum tolerated dose of an oncolytic adenovirus, a mutated virus engineered to selectively replicate in and destroy cancer tissue, in combination with fractionated stereotactic radiosurgery among patients who are undergoing resection of a recurrent high-grade astrocytoma brain tumor.

8 Jun 2023

DNA study sheds light on how we maintain healthy blood sugar levels after meals

A study of the DNA of more than 55,000 people worldwide has shed light on how we maintain healthy blood sugar levels after we have eaten, with implications for our understanding of how the process goes wrong in type 2 diabetes.

8 Jun 2023

Genome News and Research

Mapping the evolutionary timeline and population distribution of E. coli’s protective outer capsule

Complete genomics announces updated mission and new partnerships on 18th anniversary

New method of insulin delivery lowers the risk of hypoglycemia compared to current diabetes treatments

Understanding the developmental link: vitamin D's role in metabolic disease risk

Tracing the ancestry of hybrids using a new method

Berlin scientists further improve nasal vaccine against coronavirus

ACMG publishes updated recommendations for CFTR carrier screening

Breaking barriers: hydrogel reservoir unleashes the potential of HSV-1 virotherapy in cancer

Blood culture vs. metagenomic next-generation sequencing for the detection of pathogenic microbes in patients with suspected bloodstream infections

"Homing gene drive system" could help suppress agricultural pests

Scientists find clues to how we maintain constant blood sugar levels after meals

Study offers novel insights into the evolution of multiple myeloma

Study unveils potential early detection algorithm for neurodegeneration in rare genetic disorder

Common genetic factors could be used to identify individuals at high risk of developing colorectal cancer

Scientists use machine learning to unveil new predictors of post-menopausal breast cancer

AI system in eye scans enables better diagnosis of inherited retinal diseases

ABCC9 gene variants influence the pitch of voices

The BABY1000 study: chasing lifetime risk factors in prenatal and early postnatal life

Study may help advance data on oncolytic adenovirus mediated double suicide-gene therapy for high-grade brain tumors

DNA study sheds light on how we maintain healthy blood sugar levels after meals

The art of CRISPR: The power and promise of gene editing eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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