Insulin Resistance News and Research

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Insulin Resistance is a condition in which the body does not respond to insulin properly. This is most common in Type II diabetes or associated with obesity, ketoacidosis, infection, and certain rare conditions. Diminished effectiveness of insulin in lowering blood glucose levels requiring 200 units or more of insulin per day to prevent hyperglycemia or ketosis.

Obesity may accelerate the onset of type 1 diabetes in some

Obesity, long known as a cause of type II diabetes, may accelerate the onset of type 1 diabetes in some - but not all - groups of younger patients, according to research at Wake Forest University School of Medicine and six clinical sites nationally.

5 Feb 2006

Can rimonabant slow atherosclerosis?

Researchers at the University of Rochester Medical Center has announced that they have launched a study to determine whether an experimental drug, rimonabant, can slow atherosclerosis, the fatty build-up in arteries that creates heart attack risk.

2 Feb 2006

Brain plays a major role in the ability of insulin therapy to lower blood sugar in animals with diabetes

"Our findings suggest that, in individuals with diabetes, the ability of insulin to lower blood sugar involves the brain," said senior author of the study, Michael Schwartz of the University of Washington at Seattle. "This effect is not trivial; the brain makes a substantial contribution to insulin response."

10 Jan 2006

Carbohydrates improve insulin control

It is commonly believed that carbohydrates, particularly sugar, are a cause of insulin resistance and type 2 diabetes. However, such thinking has been challenged following the publication of a thorough appraisal of the evidence, in the latest edition of Nutrition Research Reviews.

10 Jan 2006

Study finds short-term lifestyle changes improve health even without major weight loss

Obese and overweight individuals suffering metabolic syndrome and Type 2 diabetes showed significant health improvements after only three weeks of diet and moderate exercise even though the participants remained overweight.

10 Jan 2006

Molecular link between high fat diets and type 2 diabetes established

Howard Hughes Medical Institute researchers have discovered a molecular link between a high-fat, Western-style diet, and the onset of type 2 diabetes. In studies in mice, the scientists showed that a high-fat diet disrupts insulin production, resulting in the classic signs of type 2 diabetes.

29 Dec 2005

Diets bad for your mental health

British psychologists say that skinny people are more likely to be unhappy and commit suicide than those who are overweight.

14 Dec 2005

Suddenly sugar isn't looking so sweet

University of Florida researchers have identified one possible reason for rising obesity rates, and it all starts with fructose, found in fruit, honey, table sugar and other sweeteners, and in many processed foods.

7 Dec 2005

2 million American children at risk of diabetes

According to a new study, as many as 2 million children in the U.S. aged 12 to 19 have a prediabetic condition or prediabetes, that is often linked to obesity and physical inactivity.

8 Nov 2005

Rate of weight gain, not the degree of fatness at any one time, which is the main predictor of future problems

Research published today indicates that the risk of heart disease in adulthood is more strongly related to how quickly children gain weight between the ages of two and eleven than their actual body weight at any particular age. Scientists believe this is linked to differences in insulin processing in later life.

27 Oct 2005

Growth patterns before birth, after birth and into childhood reveal a risk of coronary heart disease later in life

The risk of developing coronary heart disease as an adult is more strongly related to childhood growth patterns than body weight at any particular point in development, according to a new study published in the Oct. 27 New England Journal of Medicine. Coronary heart disease is the leading cause of death in the United States.

27 Oct 2005

Association of aprotinin with reduced glucose levels during CABG surgery

An anesthesiology research team at Columbia University Medical Center have completed the first human study to show that aprotinin, a protease inhibitor, was associated with lower blood glucose levels during coronary artery bypass graft (CABG) surgery.

25 Oct 2005

Sleletal muscle findings highlight the importance of exercise in obese people

The findings suggest that muscle bears a metabolic memory of obesity, which may help to explain why sustained weight loss can be difficult despite cutting calories, according to the researchers. Exercise might more successfully override the aberrant metabolic program in muscle, they suggest, thereby improving the long-term prognosis of those prone to obesity.

11 Oct 2005

Vanadium may help prepare the body to recover speedily from infections

Dietary supplements containing vanadium are used by body builders to help beef up muscles and by some diabetic people to control blood sugar. New research now suggests the naturally occurring but easily toxic element may help prepare the body to recover speedily from infections from gram-negative organisms such as E. coli.

11 Oct 2005

Obese Zucker rat model shares the symptoms of obesity with a growing number of Americans

A mutant rat that mimics a 400-pound human is helping scientists understand early vascular changes that make walking a pain for more than 2 million Americans.

9 Oct 2005

Children enrolled in fitness-oriented gym classes showed greater loss of body fat

Overweight children who took part in lifestyle-focused, fitness-oriented gym classes showed significant improvement in body composition, fitness, and insulin levels, according to a study in the October issue of Archives of Pediatrics and Adolescent Medicine.

3 Oct 2005

Increlex - first major innovation in 20 years for the treatment of growth failure

Rush University Medical Center is participating in a clinical trial to evaluate the potential benefit of the first major innovation in 20 years for the treatment of growth failure.

26 Sep 2005

Chronically high levels of insulin may block specific hormones that trigger energy release into the body

Their findings, which may point to new approaches to developing improved treatment options for the disease, are published in the journal Nature.

26 Sep 2005

Smoking may increase the risk of developing diabetes

The surprising finding emerged when researchers examined the relationship between smoking and diabetes among participants in a major national study, the Insulin Resistance Atherosclerosis Study (IRAS).

26 Sep 2005

Study clarifies insulin's role in blocking release of energy in patients with type II diabetes

Chronically high levels of insulin, as is found in many people with obesity and Type II diabetes, may block specific hormones that trigger energy release into the body, according to researchers at the University of California, San Diego (UCSD) School of Medicine.

22 Sep 2005

Insulin Resistance News and Research

Further Reading

Obesity may accelerate the onset of type 1 diabetes in some

Can rimonabant slow atherosclerosis?

Brain plays a major role in the ability of insulin therapy to lower blood sugar in animals with diabetes

Carbohydrates improve insulin control

Study finds short-term lifestyle changes improve health even without major weight loss

Molecular link between high fat diets and type 2 diabetes established

Diets bad for your mental health

Suddenly sugar isn't looking so sweet

2 million American children at risk of diabetes

Rate of weight gain, not the degree of fatness at any one time, which is the main predictor of future problems

Growth patterns before birth, after birth and into childhood reveal a risk of coronary heart disease later in life

Association of aprotinin with reduced glucose levels during CABG surgery

Sleletal muscle findings highlight the importance of exercise in obese people

Vanadium may help prepare the body to recover speedily from infections

Obese Zucker rat model shares the symptoms of obesity with a growing number of Americans

Children enrolled in fitness-oriented gym classes showed greater loss of body fat

Increlex - first major innovation in 20 years for the treatment of growth failure

Chronically high levels of insulin may block specific hormones that trigger energy release into the body

Smoking may increase the risk of developing diabetes

Study clarifies insulin's role in blocking release of energy in patients with type II diabetes

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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