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Monoclonal antibody shows promise in slowing progression of ALS

New research reveals a type of monoclonal antibody already tested in certain forms of cancer may be a promising treatment in stopping the progression of amyotrophic lateral sclerosis, or ALS, a fatal neurodegenerative disease.

31 Jul 2023

Tiny amounts of hydrogen sulfide could help people live healthier for longer

Future therapies to help people live healthy lives for longer could be developed from drugs that release tiny amounts of the gas hydrogen sulfide (H2S), new research has indicated.

31 Jul 2023

Low levels of 'memory strengthening protein' may serve as early predictor of mild cognitive impairment

Results of a long-term, federally funded study of cognitively healthy adults — most with a family history of Alzheimer's disease — have added to evidence that low spinal fluid levels of a protein linked to learning and memory in mice may serve as an early predictor of mild cognitive impairment (MCI) years before symptoms appear.

31 Jul 2023

$11.5 million award renewal from NIH supports study of how stress influences cardiovascular health

Psychosocial stress profoundly affects people's lives globally, not least because it can be a critical risk factor for cardiovascular disease.

31 Jul 2023

Researchers discover new spiroindolin-1,2-diazepine derivatives with anti-Alzheimer therapeutic potential

In a recent study, researchers designed substituted spiro indolin-1,2-diazepine derivatives '5a–v' with cholinesterase inhibitory activities as anti-Alzheimer's disease agents.

31 Jul 2023

Stem cells offer new hope for Crohn's disease treatment

Research from Ann & Robert H. Lurie Children's Hospital of Chicago found that direct injection of neonatal mesenchymal stem cells, derived from heart tissue discarded during surgery, reduces intestinal inflammation and promotes wound healing in a mouse model of Crohn's disease-like ileitis, an illness marked by chronic intestinal inflammation and progressive tissue damage.

28 Jul 2023

Penn Medicine researchers identify new therapeutic target for Alzheimer's disease

A gene encoding a protein linked to tau production - tripartite motif protein 11 (TRIM11) - was found to suppress deterioration in small animal models of neurodegenerative diseases similar to Alzheimer's disease (AD), while improving cognitive and motor abilities, according to new research from the Perelman School of Medicine at the University of Pennsylvania.

27 Jul 2023

New gene editing approach could revolutionize the treatment of blood disorders

In a step forward in the development of genetic medicines, researchers at Children's Hospital of Philadelphia (CHOP) and the Perelman School of Medicine at the University of Pennsylvania have developed a proof-of-concept model for delivering gene editing tools to treat blood disorders, allowing for the modification of diseased blood cells directly within the body.

27 Jul 2023

New technology could help amputees feel temperature in their phantom limbs

Johns Hopkins Applied Physics Laboratory (APL) researchers have developed one of the world's smallest, most intense and fastest refrigeration devices, the wearable thin-film thermoelectric cooler (TFTEC), and teamed with neuroscientists to help amputees perceive a sense of temperature with their phantom limbs.

27 Jul 2023

Harvard researchers develop ink that enables 3D printing of beating heart tissues

Over the last decade, advances in 3D printing have unlocked new possibilities for bioengineers to build heart tissues and structures.

27 Jul 2023

New collaboration to investigate forms of RNA modification

Universität Mainz Institute of Pharmaceutical and Biomedical Sciences of Mainz University to collaborate with Monash University and ETH Zurich to investigate forms of RNA modification.

27 Jul 2023

More steps linked to improved health for heart failure patients

Mammary fat tissue plays a more active role in breast biology than previously thought

An Icahn School of Medicine at Mount Sinai study sheds light on the intricate interplay between mammary adipose (fat) tissue and breast health, and offers exciting possibilities for understanding breast development, lactation, cancer, and obesity and related metabolic disorders.

26 Jul 2023

Study sheds light on how breast cancer spreads to lymph nodes

Lymph nodes are one of the body's first lines of defense against disease. Immune cells are dispatched from these biological police stations to fight off intruders.

26 Jul 2023

Children's Colorado announces launch of the Precision Medicine Institute

Children's Hospital Colorado (Children's Colorado) today announced the launch of the Precision Medicine Institute, which will allow experts to more efficiently integrate precision medicine into care provided to patients throughout the hospital.

26 Jul 2023

MD Anderson and Nexo Therapeutics partner to advance new cancer therapies against previously undruggable targets

The University of Texas MD Anderson Cancer Center and Nexo Therapeutics today announced a multi-year strategic collaboration that aligns the innovative technology and capabilities of each organization at the earliest stages of drug discovery and development to rapidly advance impactful new cancer therapies against previously undruggable targets.

26 Jul 2023

Meclofenamate shows promise in treating abnormal respiratory mucus

Our respiratory system is lined with a thin fluid layer called mucus on the inside. The mucus protects us from inhaling harmful and unwanted airborne agents from germs to pollutants; it achieves this feat due to its unique gel-like texture imparted by proteins called mucins.

25 Jul 2023

Therapeutics News and Research

Monoclonal antibody shows promise in slowing progression of ALS

Tiny amounts of hydrogen sulfide could help people live healthier for longer

Low levels of 'memory strengthening protein' may serve as early predictor of mild cognitive impairment

$11.5 million award renewal from NIH supports study of how stress influences cardiovascular health

Researchers discover new spiroindolin-1,2-diazepine derivatives with anti-Alzheimer therapeutic potential

Stem cells offer new hope for Crohn's disease treatment

Penn Medicine researchers identify new therapeutic target for Alzheimer's disease

New gene editing approach could revolutionize the treatment of blood disorders

New technology could help amputees feel temperature in their phantom limbs

Harvard researchers develop ink that enables 3D printing of beating heart tissues

New collaboration to investigate forms of RNA modification

More steps linked to improved health for heart failure patients

Mammary fat tissue plays a more active role in breast biology than previously thought

Study sheds light on how breast cancer spreads to lymph nodes

Children's Colorado announces launch of the Precision Medicine Institute

MD Anderson and Nexo Therapeutics partner to advance new cancer therapies against previously undruggable targets

Meclofenamate shows promise in treating abnormal respiratory mucus

Addressing research gaps: The UK's efforts to study lung cancer in never smokers

NK:IO raises £1.2M, bringing total Seed funding to £5.1M, to advance pioneering NK cell therapy

USC study reveals key details about how cancer cells metastasize

Event guide: The Non-Opioid Pain Therapeutics Summit eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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