Alzheimer's Disease News and Research

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Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. In most people with AD, symptoms first appear after age 60. AD is the most common cause of dementia among older people, but it is not a normal part of aging. Dementia refers to a decline in cognitive function that interferes with daily life and activities. AD starts in a region of the brain that affects recent memory, then gradually spreads to other parts of the brain. Although treatment can slow the progression of AD and help manage its symptoms in some people, currently there is no cure for this devastating disease.

New compounds can provide a breakthrough in the treatment of neurodegenerative pathologies

Russian scientists have synthesized chemical compounds that can stop the degeneration of neurons in Alzheimer's, Parkinson's, and other severe brain pathologies. These substances can provide a breakthrough in the treatment of neurodegenerative pathologies.

19 Jul 2021

Autophagy disruption may be at the root of early cognitive changes in Huntington’s disease

Huntington's Disease (HD) is a progressive neurodegenerative condition characterized by motor, cognitive, and psychiatric symptoms, and motor symptoms are often preceded by cognitive changes.

15 Jul 2021

Can Biden’s plan to remove urban highways improve the health of American cities?

Mandela Parkway, a four-lane boulevard enhanced by a median with trees and a curving footpath, stretches along a 24-block section of West Oakland. It's the fruit of a grassroots neighborhood campaign to block reconstruction of an elevated freeway leveled by the Loma Prieta earthquake in 1989 and reimagine the thoroughfare to replace it.

15 Jul 2021

Metal-based molecule inhibits the build-up of Alzheimer's peptides in lab tests

In lab tests, Imperial researchers have created a metal-based molecule that inhibits the build-up of a peptide associated with Alzheimer's disease.

14 Jul 2021

Predictive model using vocal features from phone conversations can identify early signs of Alzheimer’s disease

Study shows that a machine learning-based predictive model can be trained using telephone conversations to identify early signs of Alzheimer’s disease.

14 Jul 2021

Blood test could be a simple and effective method for monitoring SARS-CoV-2 infection

A blood test that quantifies the protein ACE2, the cellular protein which allows entry of the coronavirus into cells, as well as ACE2 fragments, produced as a result of interaction with the virus, could be a simple and effective method for monitoring SARS-CoV-2 infection, according to a study led by Javier Sáez-Valero, from the UMH-CSIC Neurosciences Institute in Alicante, published in FASEB Journal.

13 Jul 2021

New approach that uses machine learning could transform drug development

Writing in the July 12, 2021 online issue of Nature Communications, researchers at University of California San Diego School of Medicine describe a new approach that uses machine learning to hunt for disease targets and then predicts whether a drug is likely to receive FDA approval.

12 Jul 2021

Gene therapy shows promise in children with devastating genetic disorder

Children with a devastating genetic disorder characterized by severe motor disability and developmental delay have experienced sometimes dramatic improvements in a gene therapy trial launched at UCSF Benioff Children's Hospitals.

12 Jul 2021

Novel method of gene therapy promises to transform the treatment of rare genetic disorder

A novel method of gene therapy is helping children born with a rare genetic disorder called AADC deficiency that causes severe physical and developmental disabilities.

12 Jul 2021

Why we may never know whether the $56,000-a-year Alzheimer’s drug actually works

The Food and Drug Administration's approval in June of a drug purporting to slow the progression of Alzheimer's disease was widely celebrated, but it also touched off alarms.

12 Jul 2021

Doctors weigh pros and cons of prescribing hot-button Alzheimer’s drug

As physicians and health policy experts debate the merits of Aduhelm, the first new drug for Alzheimer's disease approved in 18 years, patients want to know: "Will this medication help me — and how much?"

9 Jul 2021

Researchers identify potential new treatment targets for Alzheimer's disease

A research team at Washington University School of Medicine in St. Louis has identified potential new treatment targets for Alzheimer's disease, as well as existing drugs that have therapeutic potential against these targets.

8 Jul 2021

Doctors advise against off-label use of new Alzheimer's medicine for cerebral amyloid angiopathy

A novel therapy recently approved by the U.S. Food and Drug Administration for patients with Alzheimer's disease amid considerable controversy should not be prescribed by physicians off-label for cerebral amyloid angiopathy (CAA), a similar cerebrovascular condition, according to Steven Greenberg, MD, PhD, director of the Hemorrhagic Stroke Research Program at Massachusetts General Hospital (MGH) and president of the International Cerebral Amyloid Angiopathy Association (ICAAA).

7 Jul 2021

Digital technologies amplify the ability to detect subtle differences in cognitive function tests

During neuropsychological assessments, participants complete tasks designed to study memory and thinking. Based on their performance, the participants receive a score that researchers use to evaluate how well specific domains of their cognition are functioning.

6 Jul 2021

Scientists discover pathway that sheds new light on brain damage-induced cell division

Most human cells are able to repair damage by dividing at wounds.

6 Jul 2021

IU researchers developing noninvasive brain stimulation technique to treat neurological disorders

Indiana University School of Medicine researchers are developing a new, noninvasive brain stimulation technique to treat neurological disorders, including pain, traumatic brain injury (TBI), epilepsy, Parkinson's disease, Alzheimer's disease and more.

2 Jul 2021

Developing AI technology to detect early signs of Alzheimer's disease

With the support of a new grant worth $3.9 million, Michigan State University researchers are developing technology that scans speech and vocabulary patterns to catch early signs of Alzheimer's disease, the most common cause of dementia.

1 Jul 2021

Study provides renewed hope for treating Alzheimer's and Parkinson's diseases

Nanosized molecules of a particular chemical element can inhibit the formation of plaque in the brain tissues. This new discovery by researchers at Umeå University, Sweden, in collaboration with researchers in Croatia and Lithuania, provides renewed hope for novel treatments of, for instance, Alzheimer's and Parkinson's disease in the long run.

1 Jul 2021

New software tool can help identify gene regulators more efficiently

A team of scientists at the University of Illinois Chicago has developed a software tool that can help researchers more efficiently identify the regulators of genes. The system leverages a machine learning algorithm to predict which transcription factors are most likely to be active in individual cells.

1 Jul 2021

Majority of people were unprepared and did not have a pandemic plan, survey reveals

Researchers point out that if these healthy individuals had a challenging time absorbing COVID-related information, then such challenges may be even greater in people with limited educational opportunities or with neurocognitive disorders, such as Alzheimer's disease or a brain injury, due to low health literacy and impaired memory.

1 Jul 2021

Alzheimer's Disease News and Research

Further Reading

New compounds can provide a breakthrough in the treatment of neurodegenerative pathologies

Autophagy disruption may be at the root of early cognitive changes in Huntington’s disease

Can Biden’s plan to remove urban highways improve the health of American cities?

Metal-based molecule inhibits the build-up of Alzheimer's peptides in lab tests

Predictive model using vocal features from phone conversations can identify early signs of Alzheimer’s disease

Blood test could be a simple and effective method for monitoring SARS-CoV-2 infection

New approach that uses machine learning could transform drug development

Gene therapy shows promise in children with devastating genetic disorder

Novel method of gene therapy promises to transform the treatment of rare genetic disorder

Why we may never know whether the $56,000-a-year Alzheimer’s drug actually works

Doctors weigh pros and cons of prescribing hot-button Alzheimer’s drug

Researchers identify potential new treatment targets for Alzheimer's disease

Doctors advise against off-label use of new Alzheimer's medicine for cerebral amyloid angiopathy

Digital technologies amplify the ability to detect subtle differences in cognitive function tests

Scientists discover pathway that sheds new light on brain damage-induced cell division

IU researchers developing noninvasive brain stimulation technique to treat neurological disorders

Developing AI technology to detect early signs of Alzheimer's disease

Study provides renewed hope for treating Alzheimer's and Parkinson's diseases

New software tool can help identify gene regulators more efficiently

Majority of people were unprepared and did not have a pandemic plan, survey reveals

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