Proliferation News and Research

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Loss of specific protein makes breast cancers more aggressive, resistant to chemotherapy

Researchers in Italy have discovered how specific versions of a protein called Numb protect the key tumor suppressor p53 from destruction.

21 Dec 2017

Stem cells remain healthy following low-dose X-ray exposure, say biophysicists

Biophysicists have shown that following low-dose exposure to X-rays (at 80 milligrays), stem cells remain healthy, proliferate, and do not accumulate DNA damage to be passed on to their progeny. The paper was published in the journal Aging.

20 Dec 2017

Researchers uncover THOR gene involved in cancer development

It turns out Thor, the Norse god of thunder and the Marvel superhero, has special powers when it comes to cancer too.

15 Dec 2017

Study provides insights into molecular mechanisms regulating cellular fate of SCCs

Researchers at Kanazawa University report in EMBO Reports, 7 December 2017, new molecular mechanisms regulating cellular fate of squamous cell carcinomas.

15 Dec 2017

Study reveals impact of diabetes during pregnancy on baby's heart

A new study conducted at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA discovered how increased glucose levels caused either by diabetes or other factors keep heart cells from maturing normally.

13 Dec 2017

Study provides new insights into development of Sonic Hedgehog medulloblastoma

Medulloblastoma is the most common type of solid brain tumor in children. Current treatments offer limited success and may leave patients with severe neurological side effects, including psychiatric disorders, growth retardation and cognitive impairment.

13 Dec 2017

Researchers adopt new approach to treating advanced prostate cancer

Scientists have proposed a new approach to preventing the proliferation of prostate tumor cells that are no longer responding to treatment. Prostate cancer can usually be cured via surgical removal of the tumor and/or the use of radiotherapy, but in one-fifth of cases, patients also require treatment with drugs to continue removing tumor cells. However, these drugs are only effective for up to three years, after which the cancer continues to develop.

13 Dec 2017

Researchers discover new way to attack drug-resistant prostate cancer cells

In most cases, prostate cancer is cured by surgical removal of the tumor and/or by radiotherapy. However, 20% of patients will need treatment to remove tumor cells but this treatment ceases to be effective after two or three years and the cancer develops further.

13 Dec 2017

Researchers discover how high glucose levels in pregnancy affect baby's heart

Researchers at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA have discovered how high glucose levels -- whether caused by diabetes or other factors -- keep heart cells from maturing normally.

12 Dec 2017

In era of increased competition, hospitals fret over ratings

For two years, Saint Anthony Hospital here has celebrated its top-rated "A" grade from the national Leapfrog Group that evaluates hospital safety records. But this fall, when executives opened a preview of their score, they got an unwelcome surprise: a "C."

11 Dec 2017

Drug improves disease-free, overall survival after hematopoietic stem cell transplants

Results from a phase 2 clinical trial, presented by Seattle Children's Research Institute at the 59th American Society of Hematology Annual Meeting, show that the drug Abatacept (Orencia) nearly eliminated life-threatening severe acute graft-versus-host disease (GvHD) in patients receiving hematopoietic stem cell transplants.

11 Dec 2017

Simple molecular test may help predict presence of high-grade pancreatic cancers

A report in The Journal of Molecular Diagnostics, describes a new simple molecular test to detect chromosomal abnormalities -- biomarkers known as telomere fusions--in pancreatic tumor specimens and pancreatic cyst fluids.

8 Dec 2017

Fusobacterium may play role in colon cancer growth, study finds

Like nomads who carry tokens of home on their travels, colorectal cancer cells that spread to other parts of the body appear to bring several of the species of bacteria that were their companions in the colon, Dana-Farber Cancer Institute scientists report in a new study in the journal Science.

7 Dec 2017

Study shows how interplay between two key enzymes promotes brain tumor growth

Study results revealed previously unknown interplay between two key enzymes and a novel understanding of how brain cancer tumors form and spread, according to researchers at The University of Texas MD Anderson Cancer Center.

6 Dec 2017

Scientists reveal ‘anti-metastatic surveillance’ role of Caveolin-1 protein

A new study conducted at the VIB-KU Leuven Center for Cancer Biology in Belgium has labeled the protein Caveolin-1 as a high-potential pursuit in the fight against cancer.

5 Dec 2017

Novel drug combination could enhance immunotherapy responses in patients with lung cancer

Johns Hopkins Kimmel Cancer Center researchers and colleagues have identified a novel drug combination therapy that could prime nonsmall cell lung cancers to respond better to immunotherapy.

30 Nov 2017

Penn researchers reveal new approach to restart replication in cardiomyocytes after heart attack

In mammals, including humans, the cells that contract the heart muscle and enable it to beat do not regenerate after injury.

29 Nov 2017

Scientists identify new strategies used by Helicobacter pylori to target mitochondria

Helicobacter pylori is a bacterial pathogen that colonizes the stomach of approximately half of the world's population. Infection with H. pylori is acquired in childhood and lasts for decades.

29 Nov 2017

Study provides potential explanation for increased prevalence of asthma in adult women

In childhood, asthma is more common in boys than girls. But around the time of puberty, that picture reverses. By midlife women are twice as likely as men to have asthma.

29 Nov 2017

New molecule demonstrates ability to block lymphoma growth

The prestigious scientific journal Clinical Cancer Research has published a study conducted by the research group led by Dr. Francesco Bertoni of the Institute of Oncology Research, that have tested a new molecule that demonstrates its ability to inhibit lymphoma growth.

28 Nov 2017

Proliferation News and Research

Loss of specific protein makes breast cancers more aggressive, resistant to chemotherapy

Stem cells remain healthy following low-dose X-ray exposure, say biophysicists

Researchers uncover THOR gene involved in cancer development

Study provides insights into molecular mechanisms regulating cellular fate of SCCs

Study reveals impact of diabetes during pregnancy on baby's heart

Study provides new insights into development of Sonic Hedgehog medulloblastoma

Researchers adopt new approach to treating advanced prostate cancer

Researchers discover new way to attack drug-resistant prostate cancer cells

Researchers discover how high glucose levels in pregnancy affect baby's heart

In era of increased competition, hospitals fret over ratings

Drug improves disease-free, overall survival after hematopoietic stem cell transplants

Simple molecular test may help predict presence of high-grade pancreatic cancers

Fusobacterium may play role in colon cancer growth, study finds

Study shows how interplay between two key enzymes promotes brain tumor growth

Scientists reveal ‘anti-metastatic surveillance’ role of Caveolin-1 protein

Novel drug combination could enhance immunotherapy responses in patients with lung cancer

Penn researchers reveal new approach to restart replication in cardiomyocytes after heart attack

Scientists identify new strategies used by Helicobacter pylori to target mitochondria

Study provides potential explanation for increased prevalence of asthma in adult women

New molecule demonstrates ability to block lymphoma growth

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