Alzheimer's Disease News and Research

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Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. In most people with AD, symptoms first appear after age 60. AD is the most common cause of dementia among older people, but it is not a normal part of aging. Dementia refers to a decline in cognitive function that interferes with daily life and activities. AD starts in a region of the brain that affects recent memory, then gradually spreads to other parts of the brain. Although treatment can slow the progression of AD and help manage its symptoms in some people, currently there is no cure for this devastating disease.

New research receives $2 million grant to determine if meningitis, sepsis increase Alzheimer's risk

The role of peripheral and brain infections in the development of Alzheimer's disease is the focus of new research at The University of Texas Health Science Center at Houston, funded with a $2 million grant from the National Institutes of Health.

30 Jun 2021

Promising preclinical results of new dementia treatment candidate set the stage for human trials

Researchers have identified a new treatment candidate that appears to not only halt neurodegenerative symptoms in mouse models of dementia and Alzheimer's disease, but also reverse the effects of the disorders.

29 Jun 2021

LSL60101 compound improves cognitive deficit in murine models with Alzheimer’s

The LSL60101 compound, a specific ligand of the I2-IR receptors in the brain, could shed light on the development of future strategies against Alzheimer's disease.

29 Jun 2021

IU School of Medicine wins $30 million NIA funding to study Alzheimer’s disease and related dementias

National Centralized Repository for Alzheimer's Disease and Related Dementias grant has been renewed for another five years with funding expected to total $30 million from the National Institute on Aging (NIA), within the National Institutes of the Health.

29 Jun 2021

Advanced X-ray technology provides a viable pipeline for multiscale whole brain imaging

Researchers at the University of Chicago and the U.S. Department of Energy's (DOE) Argonne National Laboratory have leveraged existing advanced X-ray microscopy techniques to bridge the gap between MRI (magnetic resonance imaging) and electron microscopy imaging, providing a viable pipeline for multiscale whole brain imaging within the same brain.

29 Jun 2021

FDA's controversial decision to approve aducanumab for Alzheimer's treatment raises major ethical issues

The U.S. Food and Drug Administration's controversial decision to approve aducanumab for the treatment of Alzheimer's disease raises at least three major ethical issues that need to be addressed, states a new article in the Hastings Center Report:

29 Jun 2021

Alternative model of Alzheimer's emphasizes different set of mechanisms that lead to neurodegeneration

In the context of recent debate over the FDA's approval of aducanumab, it's refreshing to learn about a model of Alzheimer's neurodegeneration that doesn't start with the pathogenic proteins amyloid or Tau.

29 Jun 2021

New study reveals how heparan sulfate promotes amyloid deposition in various organs

Amyloid diseases, including Alzheimer's, Parkinson's, type-2 diabetes and other life-threatening diseases, involve pathologic deposits of normally soluble proteins or peptides as insoluble amyloid fibrils. When this happens in vital organs, such as the brain, kidney, liver and heart, it causes organ damage and, if left untreated, death. Unfortunately, the available treatment options are very limited.

29 Jun 2021

Alzheimer's symptoms could be due to decline in brain protein not accumulation of amyloid plaques

Experts estimate more than 6 million Americans are living with Alzheimer's dementia. But a recent study, led by the University of Cincinnati, sheds new light on the disease and a highly debated new drug therapy.

28 Jun 2021

Scientists develop a simple, noninvasive diagnostic solution for Alzheimer's disease

An international research team led by HKUST has developed a simple but robust blood test from Chinese patient data for early detection and screening of Alzheimer's disease (AD) for the first time, with an accuracy level of over 96%.

28 Jun 2021

Virtual reality can help boost brain rhythms linked to learning and memory

A new discovery in rats shows that the brain responds differently in immersive virtual reality environments versus the real world.

28 Jun 2021

Continuity of nursing care in home health visits may prevent rehospitalization for dementia patients

People with dementia receiving home health care visits are less likely to be readmitted to the hospital when there is consistency in nursing staff, according to a new study by researchers at NYU Rory Meyers College of Nursing.

25 Jun 2021

Differences in human and mouse brain cells have implications for research into neurological disorders

A UCLA-led study comparing brain cells known as astrocytes in humans and mice found that mouse astrocytes are more resilient to oxidative stress, a damaging imbalance that is a mechanism behind many neurological disorders.

25 Jun 2021

Research data on biology of Alzheimer's disease is now available to scientists

A growing trove of data to help scientists understand the biology of Alzheimer's disease among diverse populations within the context of sociocultural, behavioral and environmental factors is now available through the Institute for Translational Research at The University of North Texas Health Science Center at Fort Worth (HSC).

25 Jun 2021

Turning down glial genes can help mitigate Huntington's disease pathogenesis

The brain is not a passive recipient of injury or disease. Research has shown that when neurons die and disrupt the natural flow of information they maintain with other neurons, the brain compensates by redirecting communications through other neuronal networks.

24 Jun 2021

Non-invasive technology shows potential to overcome detrimental effects of aging and dementia

Ultrasound can overcome some of the detrimental effects of aging and dementia without the need to cross the blood-brain barrier, Queensland Brain Institute researchers have found.

24 Jun 2021

Scientists use new technology to optimize drug development for brain diseases

Dr. Hayder Amin and Dr. Caghan Kizil from the DZNE's Dresden site aim to speed up developing drugs against brain diseases through cutting-edge technology.

24 Jun 2021

More older adults may have undiagnosed dementia than previously estimated

Only 1 in 10 older adults in a large national survey who were found to have cognitive impairment consistent with dementia reported a formal medical diagnosis of the condition.

23 Jun 2021

Study focuses on retinal roughness in Alzheimer’s disease

Over recent years, the retina has established its position as one of the most promising biomarkers for the early diagnosis of Alzheimer's.

23 Jun 2021

In utero exposure to high levels of manganese, selenium may protect children from high blood pressure

Children who were exposed to higher levels of trace minerals manganese and selenium during their mothers' pregnancy had a lower risk of high blood pressure in childhood, according to a study led by researchers at the Johns Hopkins Bloomberg School of Public Health.

23 Jun 2021

Alzheimer's Disease News and Research

Further Reading

New research receives $2 million grant to determine if meningitis, sepsis increase Alzheimer's risk

Promising preclinical results of new dementia treatment candidate set the stage for human trials

LSL60101 compound improves cognitive deficit in murine models with Alzheimer’s

IU School of Medicine wins $30 million NIA funding to study Alzheimer’s disease and related dementias

Advanced X-ray technology provides a viable pipeline for multiscale whole brain imaging

FDA's controversial decision to approve aducanumab for Alzheimer's treatment raises major ethical issues

Alternative model of Alzheimer's emphasizes different set of mechanisms that lead to neurodegeneration

New study reveals how heparan sulfate promotes amyloid deposition in various organs

Alzheimer's symptoms could be due to decline in brain protein not accumulation of amyloid plaques

Scientists develop a simple, noninvasive diagnostic solution for Alzheimer's disease

Virtual reality can help boost brain rhythms linked to learning and memory

Continuity of nursing care in home health visits may prevent rehospitalization for dementia patients

Differences in human and mouse brain cells have implications for research into neurological disorders

Research data on biology of Alzheimer's disease is now available to scientists

Turning down glial genes can help mitigate Huntington's disease pathogenesis

Non-invasive technology shows potential to overcome detrimental effects of aging and dementia

Scientists use new technology to optimize drug development for brain diseases

More older adults may have undiagnosed dementia than previously estimated

Study focuses on retinal roughness in Alzheimer’s disease

In utero exposure to high levels of manganese, selenium may protect children from high blood pressure

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