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Doctors urged to rethink prescribing parkrun as a health intervention

General practitioners are now "prescribing" parkrun for their patients as part of a social prescribing initiative to promote preventative care.

9 Apr 2025

Dynamic BH3 profiling offers personalized lung cancer therapies

Eighty-five percent of diagnosed cases of lung cancer are non-small cell lung cancer (NSCLC). In this group, 5% of patients show molecular alterations in the ALK gene involved in cell multiplication.

9 Apr 2025

Relaxation methods offer temporary relief for high blood pressure

Relaxation techniques may help lower high blood pressure-at least in the short term-but the longer term effects are unclear, finds a pooled data analysis of the existing research published in the open access journal BMJ Medicine.

9 Apr 2025

QRICH1 protein discovery opens new avenues for cancer and autoimmune therapies

In a study of the immune systems of mice, scientists at Johns Hopkins Medicine say they have found a new role for a protein, QRICH1, which could become a target for drugs to dial up or down the activation of T cells to fight cancers and autoimmune diseases.

9 Apr 2025

New molecular target identified for pancreatic cancer treatment

Researchers at City of Hope®, one of the largest and most advanced cancer research and treatment organizations in the U.S. with its National Medical Center named top 5 in the nation for cancer by U.S. News & World Report, have identified a new molecular target for treating pancreatic cancer, reports a Gastroenterology study published today.

8 Apr 2025

Tolebrutinib shows promise for treating non-relapsing secondary progressive multiple sclerosis

A Cleveland Clinic-led clinical trial of tolebrutinib, an investigational oral Bruton's tyrosine kinase inhibitor, a group of drugs originally developed to treat lymphomas and related blood disorders, demonstrated a 31% delay in the onset of six-month confirmed disability progression (CDP) in patients with non-relapsing secondary progressive multiple sclerosis (SPMS).

8 Apr 2025

New drug compound prevents long COVID symptoms in mice

Researchers have shown a new drug compound can prevent long COVID symptoms in mice – a landmark finding that could lead to a future treatment for the debilitating condition.

8 Apr 2025

Experts warn of rising HIV deaths with planned aid cuts

Global deaths from HIV/AIDS and new infections could soar to levels unseen since the start of the century if planned funding cuts to foreign aid are sustained, undermining years of progress, experts warn.

8 Apr 2025

Semaglutide linked to higher risk of vision problems, FDA data analysis shows

Researchers from the University of Bern analyzed over 300,000 FDA reports and found semaglutide use was linked to a higher reporting rate of vision impairment. The findings call for further study into the ocular risks of this widely prescribed diabetes and weight loss drug.

8 Apr 2025

Single dose of osanetant reduces fear response in female mice after trauma

A new Brevia (peer-reviewed research report) published in Brain Medicine reveals that a single dose of the drug Osanetant, administered shortly after a traumatic event, significantly dampens fear expression in female mice.

8 Apr 2025

GP38 identified as key viral toxin and vaccine target in Crimean-Congo hemorrhagic fever virus research

A recent study published in Science Translational Medicine involving scientists from the U.S. Army Medical Research Institute of Infectious Diseases in collaboration with scientists from the Albert Einstein College of Medicine and the University of California-Berkeley have advanced discoveries surrounding the viral glycoprotein GP38 expressed by the Crimean-Congo hemorrhagic fever virus (CCHFV).

8 Apr 2025

New drug compound offers pain relief without opioid side effects

University of Florida scientists have helped identify a novel drug compound that selectively activates pain-altering receptors in the body, offering a potentially safer alternative to conventional pain medications.

8 Apr 2025

Wiley releases updated Maurer, Meyer, Helfer, Weber: LC-HR-MS/MS Library of Drugs, Poisons and Their Metabolites database

Wiley, one of the world's largest publishers and a global leader in research and learning, today announced the much-anticipated release of the second edition of Maurer, Meyer, Helfer, Weber: LC-HR-MS/MS Library of Drugs, Poisons, and Their Metabolites.

From John Wiley and Sons - Scientific Publishers 8 Apr 2025

New studies reveal how cytokines affect mood and behavior

Physicians have long observed a mystifying phenomenon: After a bout of infection or an autoimmune disease flare-up, some people experience prolonged mood swings, emotional dysregulation, and changes in behavior.

7 Apr 2025

AI model enhances detection of antibiotic resistance in deadly bacteria

Drug-resistant infections - especially from deadly bacteria like tuberculosis and staph - are a growing global health crisis.

7 Apr 2025

The thalamus could be a strategic target for treating cognitive dysfunction

Years ago, as a neurology resident, Chinfei Chen, MD, PhD, cared for a 20-year-old woman who had experienced a very small stroke, affecting only the thalamus.

7 Apr 2025

Vitamin C from fresh foods helps lower heart disease risk in type 2 diabetes

Low vitamin C levels are linked to higher cardiovascular disease prevalence in people with type 2 diabetes. Fresh fruit and vegetable intake is associated with higher vitamin C levels and may offer protective cardiovascular effects.

7 Apr 2025

Firings at federal health agencies decimate offices that release public records

Public access to government records that document the handling of illnesses, faulty products, and safety lapses at health facilities will slow after mass firings at the federal Department of Health and Human Services swept out staff members responsible for releasing records, according to transparency advocates and health experts.

7 Apr 2025