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Understanding the molecular basis of how THC cannabinoid inhibits an important human enzyme

In various European countries and North America, medical cannabis or medicines based on cannabinoids are authorized for therapeutic purposes.

9 Jan 2023

Compounds derived from B.C. sea sponge can prevent COVID-19 infection in human cells

UBC researchers have identified three compounds that prevent COVID-19 infection in human cells, derived from natural sources including a B.C. sea sponge.

9 Jan 2023

Research findings open the door to new strategies for promoting muscle function during aging

Proven to protect against a wide array of diseases, exercise may be the most powerful anti-aging intervention known to science.

5 Jan 2023

Researchers reveal previously unknown properties of T cells

Certain T cells can secrete cytokines that are normally part of the innate immune system, as researchers from the Leibniz Institute for Natural Product Research and Infection Biology and an international research team discovered.

5 Jan 2023

Researchers elucidate the mechanism behind the formation of pores in mitochondrial membrane

Mitochondria are considered to be the power plants of cells and are essential for human metabolism. Dysfunction in 40 percent of mitochondrial proteins are associated with human diseases, which is why mitochondria also play an important role in medical research.

5 Jan 2023

Scientists pinpoint the routes taken by SARS-CoV-2 to enter and exit cells in our nasal cavity

Somebody just coughed on you. On a plane. At a dinner party. In a supermarket line. If only there were a "morning after" nasal spray that could knock out respiratory viruses' ability to colonize your nose and throat.

5 Jan 2023

Mediterranean diet may benefit health in part by incorporating moderate wine consumption

Many public health warnings have been issued against alcohol consumption, even in small quantities, though the evidence for such strict limits is controversial. The current study, published in the MDPI journal Nutrients, is a narrative review focused on clearing up some of the confusion associated with alcoholic drinks.

4 Jan 2023

Researchers discover novel candidate drug targets for advanced non-alcoholic fatty liver disease

Using the latest technologies - including both single-nuclear sequencing of mice and human liver tissue and advanced 3D glass imaging of mice to characterize key scar-producing liver cells - researchers have uncovered novel candidate drug targets for non-alcoholic fatty liver disease (NAFLD).

4 Jan 2023

Physical activity inhibits the production of insulin

When a fruit fly starts walking or flying, its insulin-producing cells are immediately inhibited. This could be one explanation for why exercise promotes health.

4 Jan 2023

Novel experimental approach slows physical decline and extends the lives of roundworms

Scientists in aging research today report a novel experimental approach that slowed the rate of physical decline and lengthened the lives of roundworms commonly used in biological studies, C. elgans.

30 Dec 2022

UKB resident awarded the C. E. Alken Prize for outstanding scientific uro-oncological research

Dr. Niklas Klümper, resident at the Clinic for Urology and working group leader at the Institute for Experimental Oncology at the University Hospital Bonn (UKB), was awarded the C. E. Alken Prize in recognition of his outstanding scientific uro-oncological work.

30 Dec 2022

Study suggests a strategy for preventing the progression of chronic leukemia to aggressive disease

A study from Washington University School of Medicine in St. Louis suggests a strategy for preventing a chronic, slow-growing type of blood cancer from progressing to an aggressive form of leukemia.

29 Dec 2022

Scientists explore efficacy of small molecule drugs against severe COVID-19 in vitro

Researchers evaluated the efficacy of small molecule drugs against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in vitro.

29 Dec 2022

Checkerboard-like arrangement of inner ear cells vital for hearing, research reveals

A Japanese research group has become the first to reveal that the checkerboard-like arrangement of cells in the inner ear's organ of Corti is vital for hearing.

27 Dec 2022

Researchers present a new strategy for self-adjuvanting vaccine development

This new article publication from Acta Pharmaceutica Sinica B, discusses a fully synthetic Tn-based three-component cancer vaccine using covalently linked TLR4 ligand MPLA and iNKT cell agonist KRN-7000 as built-in adjuvant effectively protects mice from tumor development.

23 Dec 2022

Research serves as a platform to identify therapeutic drugs for schizophrenia

Inflammation and overactivation of the immune system in the brain can cause loss of synapses and the death of neurons, leading to neurodegenerative and psychiatric diseases.

22 Dec 2022

Extracellular vesicles enhance cancer immunotherapy

Nano-sized membrane bubbles known as extracellular vesicles activate the immune system in mice and seem to render their tumors sensitive to a type of immunotherapy drug called a checkpoint inhibitor.

22 Dec 2022

Study could pave the way for new drug to treat hand osteoarthritis

A new study, published in Science Translational Medicine by researchers at the University of Oxford has identified that Talarozole, a drug that is known to increase retinoic acid, was able to prevent osteoarthritis (OA) in disease models.

22 Dec 2022

Sotorasib achieves meaningful anticancer activity in patients with KRAS G12C-mutated metastatic pancreatic cancer

In the Phase I/II CodeBreaK 100 trial, the KRAS G12C inhibitor sotorasib achieved meaningful anticancer activity with an acceptable safety profile in heavily pretreated patients with KRAS G12C-mutated metastatic pancreatic cancer, according to researchers at The University of Texas MD Anderson Cancer Center.

21 Dec 2022

Researchers unravel how one of the crucial early steps on the path of life could have happened

One-hundred fifty years ago, Charles Darwin speculated that life likely originated in a warm little pond. There, Darwin supposed, chemical reactions and the odd lightning strike might have led to chains of amino acids that, over time, became more and more complex until the beginnings of life emerged.

21 Dec 2022

Molecule News and Research

Understanding the molecular basis of how THC cannabinoid inhibits an important human enzyme

Compounds derived from B.C. sea sponge can prevent COVID-19 infection in human cells

Research findings open the door to new strategies for promoting muscle function during aging

Researchers reveal previously unknown properties of T cells

Researchers elucidate the mechanism behind the formation of pores in mitochondrial membrane

Scientists pinpoint the routes taken by SARS-CoV-2 to enter and exit cells in our nasal cavity

Mediterranean diet may benefit health in part by incorporating moderate wine consumption

Researchers discover novel candidate drug targets for advanced non-alcoholic fatty liver disease

Physical activity inhibits the production of insulin

Novel experimental approach slows physical decline and extends the lives of roundworms

UKB resident awarded the C. E. Alken Prize for outstanding scientific uro-oncological research

Study suggests a strategy for preventing the progression of chronic leukemia to aggressive disease

Scientists explore efficacy of small molecule drugs against severe COVID-19 in vitro

Checkerboard-like arrangement of inner ear cells vital for hearing, research reveals

Researchers present a new strategy for self-adjuvanting vaccine development

Research serves as a platform to identify therapeutic drugs for schizophrenia

Extracellular vesicles enhance cancer immunotherapy

Study could pave the way for new drug to treat hand osteoarthritis

Sotorasib achieves meaningful anticancer activity in patients with KRAS G12C-mutated metastatic pancreatic cancer

Researchers unravel how one of the crucial early steps on the path of life could have happened

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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