Nephrology News and Research

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Nephrology is a branch of internal medicine and pediatrics dealing with the study of the function and diseases of the kidney.

An alternative approach to augmenting the effect of antibiotics in chronic CF lung infections

There are about 77,000 people known to have cystic fibrosis. That's from the various cystic fibrosis registries available globally. The World Health Organization suggests that this number may be low, because there's no reporting on cystic fibrosis from the developing world. The accepted number, at the moment, is about 80,000. That's the one that is used for most of the work that's being done on cystic fibrosis.

From Neem Biotech 3 Nov 2017

Research reveals presence of potential autoantigen in patients with aggressive kidney disease

New research reveals the presence of abundant levels of a certain protein in the kidneys of patients with fibrillary glomerulonephritis (FGN). In FGN, large amounts of protein become trapped in the millions of filtering units - or glomeruli - that make up the kidney.

3 Nov 2017

Computers can alert doctors of acute kidney injury earlier to help save lives

Embedding a decision support tool in the hospital electronic health record increases detection of acute kidney injury, reducing its severity and improving survival, according to new research from the University of Pittsburgh and UPMC.

2 Nov 2017

First-of-its-kind nonsynthetic, decellularized graft one step closer to clinical trials

Researchers at the University of Minnesota have created a new lab-grown blood vessel replacement that is composed completely of biological materials, but surprisingly doesn't contain any living cells at implantation. The vessel, that could be used as an "off the shelf" graft for kidney dialysis patients, performed well in a recent study with nonhuman primates.

1 Nov 2017

Topical gel made from blood pressure pills holds great promise in healing chronic wounds

An international team of researchers led by Johns Hopkins has shown that a topical gel made from a class of common blood pressure pills that block inflammation pathways speeds the healing of chronic skin wounds in mice and pigs.

1 Nov 2017

Integrated care enhances clinical outcomes for dialysis patients

DaVita Kidney Care, a division of DaVita Inc., a leading provider of kidney care services in the United States, today announced results of the first performance year in the Centers for Medicare and Medicaid Services Comprehensive ESRD Care Model as an ESRD Seamless Care Organization.

31 Oct 2017

Air pollution linked to mortality from kidney, bladder and colorectal cancer

Air pollution is classified as carcinogenic to humans given its association with lung cancer, but there is little evidence for its association with cancer at other body sites. In a new large-scale prospective study led by the Barcelona Institute of Global Health, an institution supported by the "la Caixa" Foundation, and the American Cancer Society, researchers observed an association between some air pollutants and mortality from kidney, bladder and colorectal cancer.

31 Oct 2017

Alzheimer's disease could be triggered by breakdowns from other parts of the body

Alzheimer's disease, the leading cause of dementia, has long been assumed to originate in the brain. But research from the University of British Columbia and Chinese scientists indicates that it could be triggered by breakdowns elsewhere in the body.

31 Oct 2017

New discovery challenges basic assumptions about the brain's cellular makeup

A discovery made by Junhwan Kim, PhD, assistant professor at The Feinstein Institute for Medical Research, is challenging science's longstanding beliefs regarding the cellular makeup of the brain. This breakthrough was outlined in a study recently published in the journal Molecular and Cellular Biochemistry.

30 Oct 2017

Kidney transplantation may offer survival benefit for patients on long-term dialysis

A new study finds that kidney transplantation prolongs the lives of not only patients who have recently initiated dialysis, but also those who have been undergoing dialysis for more than a decade.

27 Oct 2017

Review emphasizes need for more hypertension research in females

Women account for half of all cases of high blood pressure (hypertension) in the U.S., yet the majority of hypertension research focuses on men.

26 Oct 2017

Penn researchers awarded $3.75 million grant to investigate how meal timings affect human health

Disrupting sleep-wake cycles from a predominantly daytime to a delayed eating lifestyle, -- i.e., skipping breakfast and making lunch the first meal of the day, plus eating late dinner, disrupts the body's natural circadian (24-hour) rhythm, the cycle that tells us when to sleep, wake up, eat, and influences hormones and other functions.

26 Oct 2017

Report: Overall burden of kidney disease remains high in the U.S.

According to an annual data report from the United State Renal Data System, the overall burden of kidney disease remains high in U.S. with the rates of kidney failure requiring dialysis or kidney transplantation ranking among the highest in the world.

26 Oct 2017

Scientists explore popular pre-heart transplant therapy’s impact on kidney function

Scientists, nephrologists and cardiac surgeons from The Feinstein Institute for Medical Research and Northwell Health's Department of Internal Medicine, Cardiology and Cardio-Thoracic Surgery examined the impact of a popular pre-heart transplant therapy on the kidney in a study published today by The Clinical Journal of the American Society of Nephrology.

26 Oct 2017

Single infusion of wildtype HSPCs halts cellular damage caused by neuromuscular disorder in mice

Researchers at University of California San Diego School of Medicine report that a single infusion of wildtype hematopoietic stem and progenitor cells (HSPCs) into a mouse model of Friedreich's ataxia (FA) measurably halted cellular damage caused by the degenerative disease.

25 Oct 2017

Researchers find rare genetic variants that may help explain longevity in some CF patients

Cystic fibrosis is an inherited disorder caused by genetic mutations that disrupt the normal movement of chloride in and out of cells. Among other health problems, cystic fibrosis compromises the lungs' ability to fight infection and breathe efficiently, making it the most lethal genetic disease in the Caucasian population. Patients have an average lifespan of just 30 to 40 years.

25 Oct 2017

Nephrology News and Research

Further Reading

An alternative approach to augmenting the effect of antibiotics in chronic CF lung infections

Research reveals presence of potential autoantigen in patients with aggressive kidney disease

Computers can alert doctors of acute kidney injury earlier to help save lives

First-of-its-kind nonsynthetic, decellularized graft one step closer to clinical trials

Topical gel made from blood pressure pills holds great promise in healing chronic wounds

Integrated care enhances clinical outcomes for dialysis patients

Air pollution linked to mortality from kidney, bladder and colorectal cancer

Alzheimer's disease could be triggered by breakdowns from other parts of the body

New discovery challenges basic assumptions about the brain's cellular makeup

Kidney transplantation may offer survival benefit for patients on long-term dialysis

Review emphasizes need for more hypertension research in females

Penn researchers awarded $3.75 million grant to investigate how meal timings affect human health

Report: Overall burden of kidney disease remains high in the U.S.

Scientists explore popular pre-heart transplant therapy’s impact on kidney function

Single infusion of wildtype HSPCs halts cellular damage caused by neuromuscular disorder in mice

Researchers find rare genetic variants that may help explain longevity in some CF patients

UH professors developing new home test kit for kidney nephritis

Robot-assisted surgery may not be time- or cost-effective compared with conventional procedure

Research identifies molecular mechanism that causes kidney cancer to resist drug treatment

New set of guidelines released for managing and caring patients with mitochondrial disease

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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