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Researchers reveal impact of genetic ancestry on breast cancer risk and cell diversity

Researchers map the diverse cell types present in healthy breast tissue to elucidate the role of genetic ancestry in breast cancer risk.

20 Aug 2024

The gut barrier plays key role in colorectal cancer prognosis

A new review was published in Oncotarget's Volume 15 on August 14, 2024, entitled, "The gut barrier as a gatekeeper in colorectal cancer treatment."

19 Aug 2024

Advancements in neoantigen vaccines offer hope for personalized cancer therapy

The saga of cancer treatment is marked by a relentless pursuit of effectiveness against a disease characterized by complexity and adaptability.

19 Aug 2024

Symptom-triggered testing shows promise for identifying early-stage ovarian cancer

Researchers evaluate the efficacy of symptom-triggered testing in detecting early-stage ovarian cancer.

19 Aug 2024

New exosome-based drug delivery system enhances ovarian cancer treatment

Ovarian cancer is one of the most common malignancies in women worldwide. Unlike breast cancer, ovarian cancer lacks early diagnostic markers and does not show noticeable symptoms until cancer metastases, leading to a low survival rate for ovarian cancer patients.

16 Aug 2024

Study highlights LLPS's influence on signaling pathways and disease progression

This paper, led by Professor Wu (Wenzhou Institute University, Wenzhou Medical University) and Professor Huang (Northeastern University), explores LLPS, a phenomenon closely associated with various diseases, including cancer and neurodegenerative disorders.

16 Aug 2024

Advancements in MRI brain tumor segmentation with improved U-net model

The brain is responsible for the "general command" of human thinking and coordination of the body.

16 Aug 2024

New nanobody shows potential in preventing lung metastasis of breast tumor cells

A new research paper was published in Oncotarget's Volume 15 on August 14, 2024, entitled, "A nanobody against the V-ATPase c subunit inhibits metastasis of 4T1-12B breast tumor cells to lung in mice."

16 Aug 2024

Ribonucleic acid for injection II enhances immunity and hematopoiesis in immunosuppressed mice

Announcing a new publication for Acta Materia Medica journal. Ribonucleic acid for injection II is a clinical adjuvant cancer therapy treatment based on immunotherapy, which exerts its effects by enhancing immune function and suppressing tumor growth.

16 Aug 2024

Saliva test offers hope for head and neck cancer patients

But what if a mouthwash-based test to detect biomarkers can help physicians predict disease recurrence in head and neck cancer patients?

16 Aug 2024

Weill Cornell Medicine secures $12.4 million grant for lymphoma research

Weill Cornell Medicine has received a five-year, $12.4 million grant from the National Cancer Institute, part of the National Institutes of Health, for an extensive program of basic and translational research on the biology of diffuse large B-cell lymphoma (DLBCL), the most common form of lymphoma.

15 Aug 2024

Neoadjuvant immunotherapy yields comparable outcomes in high-risk liver cancer surgery

Patients with liver cancer who received immune checkpoint inhibitors (ICIs) before surgery - including those who would not have been eligible for surgery by conventional criteria - had similar outcomes to patients who received surgery upfront, according to results from a retrospective study.

15 Aug 2024

The FDA calls them ‘recalls,’ yet the targeted medical devices often remain in use

In 2016, medical device giant Abbott issued a recall for its MitraClip cardiac device — "a Class I recall, the most serious type," the FDA said.

15 Aug 2024

New research gives unprecedented view of colorectal cancer genetic makeup

Researchers provided a comprehensive genomic characterization of colorectal carcinoma, a type of cancer that starts in the colon or rectum, through whole-genome sequencing of 2,023 samples, identifying novel driver genes, molecular subgroups, and potential clinical implications.

15 Aug 2024

Study reveals a paradigm shift in the understanding of T-lineage acute lymphoblastic leukemia

Researchers at Children's Hospital of Philadelphia (CHOP), St. Jude Children's Research Hospital (St. Jude) and the Children's Oncology Group (COG) today announced a significant paradigm shift in the understanding of T-lineage acute lymphoblastic leukemia (T-ALL), an aggressive and high-risk form of cancer, to one frequently driven by genetic changes in non-coding portions of our DNA.

14 Aug 2024

Ketogenic diet can boost efficacy of pancreatic cancer therapy

A study of fasting and the ketogenic diet reveals a new vulnerability of pancreatic tumors to an existing cancer drug.

14 Aug 2024

New targets for improved cancer immunotherapy

In the past two decades, immune checkpoint inhibitors (ICIs) have revolutionized cancer treatment, showing promising results against various solid tumors. This study reviews recent developments in ICIs, focusing on new targets like T cell immunoreceptors with Ig and ITIM domains (TIGIT), T cell immunoglobulin and mucin domain-containing protein 3 (TIM-3), and lymphocyte activation gene-3 (LAG-3). These targets aim to overcome resistance mechanisms limiting the effectiveness of current therapies, such as anti-PD-1 and anti-CTLA-4. By identifying and developing these new ICIs, researchers hope to improve treatment outcomes and provide new therapeutic options for cancer patients.

14 Aug 2024

Early detection key to beating ovarian cancer

'Symptom triggered testing', prompted by symptoms such as pain, abdominal bloating/swelling, and feeling full soon after starting to eat, can pick up early stage aggressive ovarian cancer in 1 in 4 of those affected, finds a data analysis, published online in the International Journal of Gynecological Cancer.

14 Aug 2024

Novel vaccination strategy shows promise in boosting immunity and controlling influenza spread in pigs

Study demonstrates that a novel prime/boost vaccination protocol using live-attenuated influenza vaccines effectively induces strong immune responses in pigs, offering a promising approach for future influenza vaccination strategies.

13 Aug 2024

Largest multi-omics study identifies new genetic landscapes in colorectal cancer

The Institute of Intelligent Medical Research (IIMR) of BGI Genomics, in collaboration with Sweden's Uppsala University, has published the largest multi-omics study of colorectal cancer (CRC) to date.

13 Aug 2024

Tumor News and Research

Researchers reveal impact of genetic ancestry on breast cancer risk and cell diversity

The gut barrier plays key role in colorectal cancer prognosis

Advancements in neoantigen vaccines offer hope for personalized cancer therapy

Symptom-triggered testing shows promise for identifying early-stage ovarian cancer

New exosome-based drug delivery system enhances ovarian cancer treatment

Study highlights LLPS's influence on signaling pathways and disease progression

Advancements in MRI brain tumor segmentation with improved U-net model

New nanobody shows potential in preventing lung metastasis of breast tumor cells

Ribonucleic acid for injection II enhances immunity and hematopoiesis in immunosuppressed mice

Saliva test offers hope for head and neck cancer patients

Weill Cornell Medicine secures $12.4 million grant for lymphoma research

Neoadjuvant immunotherapy yields comparable outcomes in high-risk liver cancer surgery

The FDA calls them ‘recalls,’ yet the targeted medical devices often remain in use

New research gives unprecedented view of colorectal cancer genetic makeup

Study reveals a paradigm shift in the understanding of T-lineage acute lymphoblastic leukemia

Ketogenic diet can boost efficacy of pancreatic cancer therapy

New targets for improved cancer immunotherapy

Early detection key to beating ovarian cancer

Novel vaccination strategy shows promise in boosting immunity and controlling influenza spread in pigs

Largest multi-omics study identifies new genetic landscapes in colorectal cancer

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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