Alzheimer's Disease News and Research

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Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. In most people with AD, symptoms first appear after age 60. AD is the most common cause of dementia among older people, but it is not a normal part of aging. Dementia refers to a decline in cognitive function that interferes with daily life and activities. AD starts in a region of the brain that affects recent memory, then gradually spreads to other parts of the brain. Although treatment can slow the progression of AD and help manage its symptoms in some people, currently there is no cure for this devastating disease.

An analysis links COVID-19 to brain microvascular injury and inflammation

The ongoing COVID-19 pandemic is caused by the severe acute respiratory syndrome-2 (SARS-CoV-2), an RNA virus that belongs to the family Coronaviridae. According to research, coronavirus disease 2019 (COVID-19) patients often suffer from neurological disorders like strokes, lost taste or smell, memory loss, confusion, and delirium.

13 Jun 2021

Study identifies mechanisms by which COVID-19 can lead to Alzheimer's disease-like dementia

A new Cleveland Clinic-led study has identified mechanisms by which COVID-19 can lead to Alzheimer's disease-like dementia.

11 Jun 2021

Study: cis P-tau is an early marker of vascular dementia, Alzheimer's disease

Researchers remain perplexed as to what causes dementia and how to treat and reverse the cognitive decline seen in patients.

11 Jun 2021

Systemic biomarkers show beneficial effects of aerobic exercise on brain function in older adults

Increasing evidence shows that physical activity and exercise training may delay or prevent the onset of Alzheimer's disease (AD). In aging humans, aerobic exercise training increases gray and white matter volume, enhances blood flow, and improves memory function.

10 Jun 2021

Study reveals new insights into how genes are regulated in dementia

The largest study of its kind has unveiled new insights into how genes are regulated in dementia, including discovering 84 new genes linked to the disease.

10 Jun 2021

Nose-to-brain: Nasal delivery of biopharmaceuticals to the brain

Placing medications as close as possible to the site of the disease: This sounds completely believable in theory, but is unfortunately not so simple in practice. While this works well for many drugs via the bloodstream or the digestive tract, it does not apply to the brain.

9 Jun 2021

Having trouble falling asleep associated with cognitive impairment 14 years later

A study of nearly 2,500 adults found that having trouble falling asleep, as compared to other patterns of insomnia, was the main insomnia symptom that predicted cognitive impairment 14 years later.

9 Jun 2021

Healthy behaviors can prevent dementia, finds study

A new Alzheimer's disease drug will hit the market soon, the first in nearly two decades. But some experts say the evidence for it isn't terribly strong and worry that it may cost a lot.

9 Jun 2021

New study has implications for research and advancements in Alzheimer’s and related memory disorders

Scientists have observed for the first time what it looks like in the key memory region of the brain when a mistake is made during a memory trial.

9 Jun 2021

Weak brain signals may be an early warning sign of age-related neurodegenerative diseases

Weakened electrical signals in the brain may be an early warning sign of age-related neurodegenerative diseases such as Alzheimer's disease, suggests a study published today in eLife.

8 Jun 2021

Researchers identify genomic cellular map associated with hippocampal sclerosis

A multidisciplinary team led by researchers from the Spanish Research Council identifies the genomic cellular map associated with hippocampal sclerosis, a major histopathological condition of temporal lobe epilepsy.

8 Jun 2021

Brain study may lead to new treatments for neuro-immune conditions

The immune system is the brain's best frenemy. It protects the brain from infection and helps injured tissues heal, but it also causes autoimmune diseases and creates inflammation that drives neurodegeneration.

8 Jun 2021

FDA approves monoclonal antibody aducanumab for treating Alzheimer's patients

Today's FDA approval of the monoclonal antibody Aduhelm (aducanumab) to treat patients with Alzheimer's disease reflects years of significant advances in Alzheimer's research. This is the first new Alzheimer's drug approved in 17 years and the first shown to modify the course of the disease, which FDA believes will lead to slowing of patients' cognitive decline.

8 Jun 2021

New technology can explain the effect of genetic factors on brain structure, function

Liang Zhan, assistant professor of electrical and computer engineering at Pitt's Swanson School of Engineering, received a $500,000 CAREER award from the National Science Foundation to develop computational tools that improve our understanding of the human brain.

8 Jun 2021

Discovery offers a potential new pathway to treat hypertension

High blood pressure, or hypertension, is the leading modifiable risk factor for cardiovascular diseases and premature death worldwide.

7 Jun 2021

FDA grants accelerated approval for first-of-its-kind Alzheimer's treatment

Today, the U.S. Food and Drug Administration approved Aduhelm (aducanumab) for the treatment of Alzheimer's, a debilitating disease affecting 6.2 million Americans. Aduhelm was approved using the accelerated approval pathway, which can be used for a drug for a serious or life-threatening illness that provides a meaningful therapeutic advantage over existing treatments.

7 Jun 2021

A single blood-based biomarker can help indicate underlying neurodegeneration

Levels of a protein called neurofilament light chain (NfL) in the blood can identify those who might have neurodegenerative diseases such as Down's syndrome dementia, motor neuron disease (ALS) and frontotemporal dementia, when clinical symptoms are not definitive

7 Jun 2021

Alzheimer's Disease News and Research

Further Reading

An analysis links COVID-19 to brain microvascular injury and inflammation

Study identifies mechanisms by which COVID-19 can lead to Alzheimer's disease-like dementia

Study: cis P-tau is an early marker of vascular dementia, Alzheimer's disease

Systemic biomarkers show beneficial effects of aerobic exercise on brain function in older adults

Study reveals new insights into how genes are regulated in dementia

Nose-to-brain: Nasal delivery of biopharmaceuticals to the brain

Having trouble falling asleep associated with cognitive impairment 14 years later

Healthy behaviors can prevent dementia, finds study

New study has implications for research and advancements in Alzheimer’s and related memory disorders

Weak brain signals may be an early warning sign of age-related neurodegenerative diseases

Researchers identify genomic cellular map associated with hippocampal sclerosis

Brain study may lead to new treatments for neuro-immune conditions

FDA approves monoclonal antibody aducanumab for treating Alzheimer's patients

New technology can explain the effect of genetic factors on brain structure, function

Discovery offers a potential new pathway to treat hypertension

FDA grants accelerated approval for first-of-its-kind Alzheimer's treatment

A single blood-based biomarker can help indicate underlying neurodegeneration

FDA weighs approval of a lucrative Alzheimer’s drug but benefits are iffy

Secondary infections amplify the brain's immune response and affect memory in Alzheimer's disease

Alzheimer's disease increases a threefold risk of contracting severe COVID-19 and death

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