Oncology News and Research

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Oncology, meaning bulk, mass, or tumor, and the suffix ''-logy'', meaning "study of") is a branch of medicine that deals with tumors (cancer). A medical professional who practices oncology is an ''oncologist''.

Using a gene signature to predict cancer patient's response to chemotherapy agent cisplatin

Researchers at Cleveland Clinic have taken an important step in predicting which treatment will work for individual cancer patients.

21 Apr 2023

New preservation temperature extends the lifespan of donor organ outside the body

Storing donor lungs for transplant at 10 degrees Celsius markedly increases the length of time the organ can live outside the body according to research led by a team of scientists at the Toronto Lung Transplant Program in the Ajmera Transplant Centre at the University Health Network.

20 Apr 2023

Breast cancer patients using antibiotics more likely to experience recurrence or death

Women with triple-negative breast cancer who received multiple antibiotic prescriptions within three years after their cancer diagnosis were more likely to experience disease recurrence and to die from their cancer than those who took fewer courses of the drugs, according to a study by researchers at Stanford Medicine.

20 Apr 2023

Gut bacteria could be responsible for dampening our immune response to COVID-19 vaccine

Gut bacteria that break down a sugar called fucose could be dampening our immune response to the COVID-19 mRNA vaccine, according to a study led by researchers from the Okinawa Institute of Science and Technology.

20 Apr 2023

Study uncovers a protein-protein interaction that contributes to Parkinson's disease

In a study published in Nature Communications, a team led by Krembil Brain Institute Senior Scientists, Drs. Lorraine Kalia and Suneil Kalia, and University of Toronto (U of T) Professor, Dr. Philip M. Kim, identified a protein-protein interaction that contributes to Parkinson's disease.

20 Apr 2023

First-in-human clinical study begins investigating the duoCAR T-cell therapy for treatment of HIV

UC Davis Health researchers have dosed the second participant in their clinical trial looking to identify a potential cure for HIV utilizing CAR T-cell therapy.

19 Apr 2023

Clinical trial may set a new 'gold standard' for the treatment of childhood craniopharyngioma

St. Jude Children's Research Hospital is reporting phase 2 clinical trial results treating the brain tumor craniopharyngioma with proton therapy.

19 Apr 2023

Rapamycin and other rapalogs have potential to delay cancer

A new research perspective was published in Oncotarget's Volume 14 on April 14, 2023, entitled, "Cancer prevention with rapamycin."

18 Apr 2023

SWOG investigators report results from DART clinical trial of immunotherapy combination for rare gynecologic cancers

Results from the S1609 DART clinical trial, which tested an immunotherapy combination of ipilimumab plus nivolumab in 53 cohorts of patients with rare cancers, are being reported for five cohorts of patients who had rare gynecologic cancers.

18 Apr 2023

Researchers discover the molecule responsible for guiding T cells toward tumors

Immunotherapy, particularly CAR T-Cell treatment for cancer, is extending the lives of many patients. But sometimes the therapy randomly migrates to places it shouldn't go, tucking into the lungs or other noncancerous tissue and causing toxic side effects.

18 Apr 2023

Discovery could be the key to unlocking new, more successful treatments for glioblastoma

For decades, researchers have marveled at the ability of glioblastoma, a particularly aggressive brain cancer, to turn off a patient's cancer-fighting immune cells, thereby allowing tumors to grow freely.

18 Apr 2023

Children with ALL living in extreme poverty face two-fold greater risk of relapse

Children with acute lymphoblastic leukemia (ALL) who live in extreme poverty and were undergoing maintenance therapy faced an almost two-fold greater risk of relapse compared with kids who weren't as poor, according to a study published in today's issue of Blood.

18 Apr 2023

New $2.3 million NCI grant awarded to Georgia Cancer Center to improve survival of patients with AML

Acute myeloid leukemia (AML) is a cancer that affects blood cells in the bone marrow - the spongy tissue inside certain bones, where new blood cells are made.

17 Apr 2023

Combination treatment could improve stem cell transplantation process for multiple myeloma patients

The standard treatment for patients with multiple myeloma often includes stem cell transplantation in which the patient's own stem cells are harvested and stored while the patient receives intensive chemotherapy to kill the cancer.

17 Apr 2023

Pre- and post-surgical immunotherapy-based treatment significantly improved lung cancer outcomes

A regimen of pre-surgical immunotherapy and chemotherapy followed by post-surgical immunotherapy significantly improved event-free survival (EFS) and pathologic complete response (pCR) rates compared to chemotherapy alone for patients with operable non-small cell lung cancer (NSCLC), according to Phase III trial results presented today by researchers from The University of Texas MD Anderson Cancer Center at the American Association for Cancer Research (AACR) Annual Meeting 2023.

17 Apr 2023

Experimental mRNA vaccine plus an immunotherapy reduced the likelihood of melanoma recurrence

The combination of an experimental mRNA vaccine with an immunotherapy reduced the likelihood of melanoma recurring or causing death by 44% when compared to immunotherapy alone, a new clinical trial shows.

17 Apr 2023

Many melanoma patients could avoid the risk for toxicity from combination therapies, study suggests

Data from a national clinical trial shows that a striking 89% of patients with desmoplastic melanoma responded to immunotherapy (pembrolizumab) alone, suggesting that many patients could avoid the risk for toxicity from combination therapies and achieve cancer control with this approach to treatment.

17 Apr 2023

Cedars-Sinai Cancer collaborates on a streamlined clinical trial design in Pragmatica-Lung Study

Investigators from Cedars-Sinai Cancer are collaborating on a streamlined clinical trial design in a study called Pragmatica-Lung.

12 Apr 2023

Women with multiple tumors in one breast may be able to avoid a mastectomy

Patients who have multiple tumors in one breast may be able to avoid a mastectomy if the tumors can be removed while leaving enough breast tissue, according to research led by the Alliance in Clinical Trials in Oncology and Mayo Clinic Comprehensive Cancer Center.

12 Apr 2023

Pragmatica-Lung Study aims to increase accessibility to cancer clinical trials

The National Cancer Institute, part of the National Institutes of Health (NIH), has helped launch a phase 3 randomized clinical trial (NCT05633602) of a two-drug combination to treat patients with advanced non-small cell lung cancer (NSCLC).

12 Apr 2023

Oncology News and Research

Further Reading

Using a gene signature to predict cancer patient's response to chemotherapy agent cisplatin

New preservation temperature extends the lifespan of donor organ outside the body

Breast cancer patients using antibiotics more likely to experience recurrence or death

Gut bacteria could be responsible for dampening our immune response to COVID-19 vaccine

Study uncovers a protein-protein interaction that contributes to Parkinson's disease

First-in-human clinical study begins investigating the duoCAR T-cell therapy for treatment of HIV

Clinical trial may set a new 'gold standard' for the treatment of childhood craniopharyngioma

Rapamycin and other rapalogs have potential to delay cancer

SWOG investigators report results from DART clinical trial of immunotherapy combination for rare gynecologic cancers

Researchers discover the molecule responsible for guiding T cells toward tumors

Discovery could be the key to unlocking new, more successful treatments for glioblastoma

Children with ALL living in extreme poverty face two-fold greater risk of relapse

New $2.3 million NCI grant awarded to Georgia Cancer Center to improve survival of patients with AML

Combination treatment could improve stem cell transplantation process for multiple myeloma patients

Pre- and post-surgical immunotherapy-based treatment significantly improved lung cancer outcomes

Experimental mRNA vaccine plus an immunotherapy reduced the likelihood of melanoma recurrence

Many melanoma patients could avoid the risk for toxicity from combination therapies, study suggests

Cedars-Sinai Cancer collaborates on a streamlined clinical trial design in Pragmatica-Lung Study

Women with multiple tumors in one breast may be able to avoid a mastectomy

Pragmatica-Lung Study aims to increase accessibility to cancer clinical trials

Event guide: 10th CAR-TCR Summit eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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