Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Men with inherited gene mutation have high risk of aggressive prostate cancer

Men who inherit mutations in a gene called TP53 have a high risk of developing aggressive prostate cancer, a multicenter research team in the United States has found.

2 Dec 2021

Impact of SARS-CoV-2 infection on testis function

A study published in the journal Nature Reviews Urology discusses the impact of coronavirus disease 2019 (COVID-19) on male fertility.

2 Dec 2021

Longer interval between COVID-19 mRNA vaccine doses leads to stronger immune response

The first peer-reviewed study in North America examining the timing between the first and second doses of COVID-19 mRNA vaccines shows that a longer dose interval leads to a stronger immune response. The study is funded by the Government of Canada through its COVID-19 Immunity Task Force.

1 Dec 2021

Flow Robotics and Automata collaborate to provide end-to-end lab automation

Flow Robotics A/S and Automata have teamed up and integrated the liquid handling robot, flowbot® ONE, with the robot arm, Eva.

From Flow Robotics 1 Dec 2021

Introducing the PhysioMimix™ OOC Multi-Organ Microphysiological System

CN Bio, a leading developer of single and multi-organ microphysiological systems (MPS), otherwise known as organ-on-a-chip (OOC), today announced the commercial launch of its new PhysioMimix™ OOC Multi-Organ MPS.

From CN Bio 1 Dec 2021

Novel anti-inflammatory drug target identified by CRISPR

In this interview, News-Medical speaks to Dr. Jeffrey Rathmell about his recent research into how metabolic pathways impact immune function.

1 Dec 2021

Study sheds light on Aβ deposition patterns in the brain from external sources

Alzheimer's disease (AD) involves the deposition of a protein called amyloid β protein (Aβ) in the brain. This protein can build up in both the functional tissues, or "parenchyma", of the brain, and in the blood vessels.

30 Nov 2021

'Biosensor barcodes' can identify and track how cancer cells 'talk' to each other

Ever since the first barcode appeared on a pack of chewing gum in 1974, the now-ubiquitous system has enabled manufacturers, retailers and consumers to quickly and effectively identify, characterize, locate and track products and materials.

30 Nov 2021

Northwestern researchers continue to tackle every facet of COVID-19 pandemic

As the COVID-19 pandemic nears the two-year mark, Northwestern Medicine scientists continue to tackle every facet of the disease, from investigating coronavirus vaccines' potential for providing immunity against similar coronaviruses to developing novel rapid antigen-based tests and examining disparities in COVID-19 case and mortality rates in Chicago.

30 Nov 2021

First-of-its-kind PET imaging-based tool developed to detect liver inflammation in NAFLD patients

A UC Davis Health team has developed a first-of-its-kind positron emission tomography (PET) scan imaging-based tool to detect liver inflammation in patients affected with non-alcoholic fatty liver disease.

30 Nov 2021

Study on molnupiravir precursor NHC antiviral activity against SARS-CoV-2 variants of concern

In a new study, published on the bioRxiv* preprint server, scientists aimed to determine the reaction of the molnupiravir parent drug (NHC) to different SARS-CoV-2 Variants of Concern (VoCs). They also sought to establish the therapeutic window in a human lung cell model.

29 Nov 2021

Rare variants in high-risk autism gene can alter architecture and organization of neurons, study finds

Scientists at the University of North Carolina at Chapel Hill School of Medicine and colleagues have demonstrated that rare variants in the ANK2 gene, consistently found in individuals with autism spectrum disorder (ASD), can alter architecture and organization of neurons, potentially contributing to autism and neurodevelopmental comorbidities.

29 Nov 2021

Genetic variations affect and rewire phosphorylation signaling networks in SARS-CoV-2 infection

Researchers study human single nucleotide variants (SNVs) using machine learning to identify amino acid changes that alter kinase-bound sequence motifs.

29 Nov 2021

Study shows plasmacytoid dendritic cells may be a viable target for protection against SARS-CoV-2

A recent research paper by scientists from Denmark reveals that circulating plasmacytoid dendritic cells may be a potential therapeutic target to maintain desired levels of an antiviral compound known as interferon, allowing for the mitigation of coronavirus disease (COVID-19) severity. The study is currently available on the bioRxiv* preprint server while it undergoes peer review.

28 Nov 2021

Researchers reveal possible role for anti-idiotype antibodies in long-term effects of COVID-19

With around 256 million cases and more than 5 million deaths worldwide, the COVID-19 pandemic has challenged scientists and those in the medical field.

25 Nov 2021

Experimental compound reduces diabetic complications in mice

An experimental compound reduced complications of type 1 and type 2 diabetes in mice—not by lowering blood sugar—but by countering its consequences of cell death, inflammation, and organ damage.

24 Nov 2021

Bat coronavirus ecology, evolution, and spillover

In a review published in Nature Reviews Microbiology, the authors collate information about the ecology and evolution of bat coronaviruses.

24 Nov 2021

Relaxation of COVID-19 restrictions led to the reemergence of seasonal respiratory viruses in Houston

A Houston Methodist study showed a rapid return of seasonal respiratory viruses after COVID-19 restrictions were relaxed in Texas, demonstrating the effectiveness of masking, distancing and other precautionary measures at stopping the spread of many respiratory illnesses, not just COVID-19.

24 Nov 2021

Tobacco mosaic virus nanoparticle-based novel COVID-19 vaccine candidate

Scientists generate a VLP type NP platform made of recombinant viral antigens conjugated with TMV virions.

23 Nov 2021

Covid-19 could reduce the perception of pain in oncological patients

Physicians from the Geneva University Hospitals (HUG) have observed a surprising phenomenon during the second wave of the COVID-19 pandemic: some patients with cancer-related pain have experiences a significant decrease or even disappearance of pain perception during the acute phase of infection.

22 Nov 2021

Pathology News and Research

Further Reading

Men with inherited gene mutation have high risk of aggressive prostate cancer

Impact of SARS-CoV-2 infection on testis function

Longer interval between COVID-19 mRNA vaccine doses leads to stronger immune response

Flow Robotics and Automata collaborate to provide end-to-end lab automation

Introducing the PhysioMimix™ OOC Multi-Organ Microphysiological System

Novel anti-inflammatory drug target identified by CRISPR

Study sheds light on Aβ deposition patterns in the brain from external sources

'Biosensor barcodes' can identify and track how cancer cells 'talk' to each other

Northwestern researchers continue to tackle every facet of COVID-19 pandemic

First-of-its-kind PET imaging-based tool developed to detect liver inflammation in NAFLD patients

Study on molnupiravir precursor NHC antiviral activity against SARS-CoV-2 variants of concern

Rare variants in high-risk autism gene can alter architecture and organization of neurons, study finds

Genetic variations affect and rewire phosphorylation signaling networks in SARS-CoV-2 infection

Study shows plasmacytoid dendritic cells may be a viable target for protection against SARS-CoV-2

Researchers reveal possible role for anti-idiotype antibodies in long-term effects of COVID-19

Experimental compound reduces diabetic complications in mice

Bat coronavirus ecology, evolution, and spillover

Relaxation of COVID-19 restrictions led to the reemergence of seasonal respiratory viruses in Houston

Tobacco mosaic virus nanoparticle-based novel COVID-19 vaccine candidate

Covid-19 could reduce the perception of pain in oncological patients

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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