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Prime editing reverses symptoms of severe childhood neurological disease

Scientists use a precise form of gene editing called prime editing to correct the most common genetic mutations that cause alternating hemiplegia of childhood, a rare and severe neurological disorder that begins in infancy.

21 Jul 2025

Combination of two cancer drugs could treat the most common form of dementia

A study comparing the gene expression signature of Alzheimer's disease with those elicited by 1,300 approved drugs found a combination of two cancer medications that could treat the most common form of dementia.

21 Jul 2025

Novel polysaccharide from Albizzia julibrissin shows promise against pancreatic cancer

Albizzia julibrissin is a widely distributed plant in China. Its dried stem bark has been used in traditional oriental medicine to treat insomnia, diuresis, sthenia, ascaricide, and confusion.

21 Jul 2025

Study uncovers a specialized gut-brain pathway for glucose sensing

In a groundbreaking study, a research team at KAIST has uncovered a gut-brain circuit that enables the brain to selectively recognize glucose—beyond simply registering total caloric intake.

21 Jul 2025

Myeloid cells play central role in immune response after polytrauma

Gaining insights into the complex pathways and key cell populations involved in immune dysregulation can aid the development of therapeutic approaches to treat polytrauma, which is associated with poor patient outcomes.

21 Jul 2025

Gecko-inspired nanoparticles deliver targeted chemotherapy to tumors

As far back as the 4th Century B.C., Aristotle marveled at the nimble gecko's ability to "run up and down a tree in any way, even with the head downwards."

21 Jul 2025

Fluorescent bacteria enable real-time tumor visualization during surgery

Accurate removal of tumors is the most critical aspect of cancer surgery, yet it remains a significant challenge in clinical practice.

21 Jul 2025

Georgia shows rough road ahead for states as Medicaid work requirements loom

Every time Ashton Alexander sees an ad for Georgia Pathways to Coverage, it feels like a "kick in the face."

21 Jul 2025

Sperm RNA profiles could identify the best embryos for IVF

Findings on sperm RNA suggest new biomarkers for IVF success, potentially improving embryo selection and reducing cycles needed for desired fertility outcomes.

21 Jul 2025

DeNovix releases new CellDrop FLxi applications

DeNovix announces the release of three new cell counting applications for the CellDrop FLxi Automated Cell Counter.

From DeNovix Inc. 21 Jul 2025

AI turns old diabetes drug Halicin into a potent weapon against superbugs

Researchers found that Halicin, an AI-identified drug, effectively inhibited most multidrug-resistant bacteria except Pseudomonas aeruginosa. The study highlights Halicin’s broad-spectrum antibacterial potential and the transformative role of artificial intelligence in antibiotic discovery.

20 Jul 2025

$New insights into diagnosis and treatment of tibial tubercle avulsion fractures in young athletes$

New insights into diagnosis and treatment of tibial tubercle avulsion fractures in young athletes

As youth engagement in high-energy sports surges, so does the prevalence of sport-related injuries. Among them, tibial tubercle avulsion fractures (TTAFs) represent a small but serious subset, accounting for less than 3% of pediatric fractures.

18 Jul 2025

Combination of dysbiosis, OTUD3 gene mutations, and STING signaling linked to ulcerative colitis severity

Ulcerative colitis (UC) causes misery for millions worldwide. It affects the large intestine, causing pain, cramping, and frequent bowel movements with bloody diarrhea.

18 Jul 2025

ATR FTIR spectroscopy shows high accuracy in breast tissue classification

Histopathology is the gold standard in cancer diagnosis. However, attenuated total reflectance (ATR)-Fourier transform infrared (FTIR) spectroscopy has shown diagnostic potential in other settings.

18 Jul 2025

Developing AI-driven stem cell therapies to fight ovarian aging

Ovarian aging, characterized by diminishing egg reserves and quality, affects millions of women worldwide, often leading to infertility.

18 Jul 2025

Ohio State chemists unlock easier path to develop key drug components

Chemists have developed a novel way to generate a variety of highly useful chemical building blocks by harnessing metal carbenes, suggests new research.

18 Jul 2025

Sound stress alone induces pain sensitivity and brain inflammation

Pain is an important physiological response in living organisms. While physical pain is an outcome of tissue damage, pain can manifest as diverse unpleasant sensory and emotional experiences. Many studies report that emotional or psychological stress enhances pain responses.

18 Jul 2025

Cuproptosis offers new hope for treating inflammatory bowel disease and colorectal cancer

Cuproptosis represents a novel mechanism of cell death characterized by intracellular copper ion accumulation.

18 Jul 2025

New mRNA vaccine strategy awakens immune system to fight cancer

An experimental mRNA vaccine boosted the tumor-fighting effects of immunotherapy in a mouse-model study, bringing researchers one step closer to their goal of developing a universal vaccine to "wake up" the immune system against cancer.

18 Jul 2025

Study identifies SDR42E1's role in vitamin D pathway

Vitamin D is not only an essential nutrient, but also the precursor of the hormone calcitriol, indispensable for health: it regulates the uptake of phosphate and calcium necessary for bones by the intestines, as well as cell growth and the proper function of muscles, nerve cells, and the immune system.

18 Jul 2025