Alzheimer's Disease News and Research

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Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. In most people with AD, symptoms first appear after age 60. AD is the most common cause of dementia among older people, but it is not a normal part of aging. Dementia refers to a decline in cognitive function that interferes with daily life and activities. AD starts in a region of the brain that affects recent memory, then gradually spreads to other parts of the brain. Although treatment can slow the progression of AD and help manage its symptoms in some people, currently there is no cure for this devastating disease.

Trouble managing money may be an early sign of dementia

After Maria Turner's minivan was totaled in an accident a dozen years ago, she grew impatient waiting for the insurance company to process the claim.

5 May 2021

Researchers use gene therapy to prevent learning, memory loss in Alzheimer's mouse model

Researchers at University of California San Diego School of Medicine, with colleagues elsewhere, have used gene therapy to prevent learning and memory loss in a mouse model of Alzheimer's disease (AD), a key step toward eventually testing the approach in humans with the neurodegenerative disease.

5 May 2021

$Mild depression may predict postoperative delirium in older adults undergoing hip fracture repair$

Mild depression may predict postoperative delirium in older adults undergoing hip fracture repair

Screening for even mild depressive symptoms before hip fracture repair may be helpful in predicting which patients are at higher risk of developing delirium after emergency surgery, according to results of a new study by researchers from Johns Hopkins Medicine.

4 May 2021

$3.5 million grant awarded to address the underrepresentation of Black adults in Alzheimer's research

Black adults are more likely than other groups to develop Alzheimer's disease or related disorders but are poorly represented in Alzheimer's disease research, including recent clinical trials. This health disparity illustrates how Black individuals can benefit from advances in the field if they had access.

4 May 2021

Researchers provide a promising new way to elucidate the brain's health

Researchers from the Center for BrainHealth at The University of Texas at Dallas are investigating a potential new early indicator of the decline toward Alzheimer's disease: measuring the energy metabolism of the living human brain using cutting-edge imaging techniques.

4 May 2021

Four-part small-molecule cocktail can prevent cellular stress

Researchers at the National Institutes of Health (NIH) have devised a four-part small-molecule cocktail that can protect stem cells called induced pluripotent stem cells (iPSCs) from stress and maintain normal stem cell structure and function.

4 May 2021

Low doses of ionizing radiation may be a promising therapy for people with Alzheimer’s disease

Individuals living with severe Alzheimer's disease showed remarkable improvements in behavior and cognition within days of receiving an innovative new treatment that delivered low doses of radiation, a recent Baycrest-Sunnybrook pilot study found.

3 May 2021

Researchers develop novel algorithm for the diagnostics of dementia

Researchers from the University of Eastern Finland and the University of Oulu in collaboration with an international team have created a new diagnostic biomarker-based algorithm for the diagnostics of dementia.

30 Apr 2021

Study shows how tau spreads to four distinct patterns leading to different Alzheimer's symptoms

Alzheimer's disease is characterized by the abnormal accumulation and spread of the tau protein in the brain. An international study can now show how tau spreads according to four distinct patterns that lead to different symptoms with different prognoses of the affected individuals.

30 Apr 2021

BrainMap analysis strongly affirms 'network degeneration hypothesis' theory

The brain possesses a complex architecture of functional networks as its information-processing machinery. Is the brain's network architecture itself a target of disease? If so, which networks are associated with which diseases? What can this tell us about the underlying causes of brain disorders?

29 Apr 2021

High-powered MRI detects subtle differences in the hippocampus of people with Down syndrome

Using ultra-high field magnetic resonance imaging (MRI) to map the brains of people with Down syndrome (DS), researchers from Case Western Reserve University, Cleveland Clinic, University Hospitals and other institutions detected subtle differences in the structure and function of the hippocampus--a region of the brain tied to memory and learning.

29 Apr 2021

Repairing faulty drains could be key to unlocking the potential of Alzheimer's therapies

Experimental Alzheimer's drugs have shown little success in slowing declines in memory and thinking, leaving scientists searching for explanations.

29 Apr 2021

New breakthrough method for quickly, accurately diagnosing cardiac arrhythmias

Researchers from Belgium, the Netherlands, Russia, and Italy have developed a breakthrough method for quickly, accurately, and reliably diagnosing cardiac arrhythmias.

27 Apr 2021

UCI biologists develop new mouse model to study late-onset Alzheimer's disease

University of California, Irvine biologists have developed a new genetically engineered mouse model that, unlike its predecessors, is based on the most common form of Alzheimer's disease.

27 Apr 2021

Traumatic brain injury and Alzheimer's disease share common trajectories

Brain changes in people with Alzheimer's disease and in those with mild traumatic brain injuries (TBIs) have significant similarities, a new USC study shows, suggesting new ways to identify patients at high risk for Alzheimer's.

26 Apr 2021

Researchers assess the theoretical impact of biomarker framework on dementia prediction

One of the biggest challenges in Alzheimer's research is to identify biomarkers that can identify people who are at risk of developing dementia. Biomarkers could be used to screen people so they might be helped before they develop dementia.

26 Apr 2021

Researchers create a cell library to study how various sugars bind to and interact with receptors

Most infectious bacteria and viruses bind to sugars on the surface of our cells. Now researchers from the University of Copenhagen have created a library of tens of thousands of natural cells containing all the sugars found on the surface of our cells.

23 Apr 2021

Alzheimer's Disease News and Research

Further Reading

Trouble managing money may be an early sign of dementia

Researchers use gene therapy to prevent learning, memory loss in Alzheimer's mouse model

Mild depression may predict postoperative delirium in older adults undergoing hip fracture repair

$3.5 million grant awarded to address the underrepresentation of Black adults in Alzheimer's research

Researchers provide a promising new way to elucidate the brain's health

Four-part small-molecule cocktail can prevent cellular stress

Low doses of ionizing radiation may be a promising therapy for people with Alzheimer’s disease

Researchers develop novel algorithm for the diagnostics of dementia

Study shows how tau spreads to four distinct patterns leading to different Alzheimer's symptoms

BrainMap analysis strongly affirms 'network degeneration hypothesis' theory

High-powered MRI detects subtle differences in the hippocampus of people with Down syndrome

Repairing faulty drains could be key to unlocking the potential of Alzheimer's therapies

New breakthrough method for quickly, accurately diagnosing cardiac arrhythmias

UCI biologists develop new mouse model to study late-onset Alzheimer's disease

Traumatic brain injury and Alzheimer's disease share common trajectories

Researchers assess the theoretical impact of biomarker framework on dementia prediction

Researchers create a cell library to study how various sugars bind to and interact with receptors

Experimental drug reverses key symptoms of Alzheimer's disease in mice

Stem cell therapy can repair brain damage and improve memory function in mice

Listening to music can help older adults sleep better, finds study

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