Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Physical activity may reduce immune cell activation to improve brain health in Alzheimer's disease

No one will disagree that an active lifestyle is good for you, but it remains unclear how physical activity improves brain health, particularly in Alzheimer's disease.

22 Nov 2021

Monitoring cellular metabolism for NAFLD/NASH liver disease research

In this interview, Jolanta Vidugiriene, a Senior Research Scientist at Promega Corporation, talks to News-Medical about tools for studying metabolism in NAFLD/NASH research.

From Promega Corporation 22 Nov 2021

Adolescents with multiple concussions show disruption in the brain's default mode network

Adolescents and young adults with post-concussive symptoms who suffered three to five concussions showed disruption in the default mode network, an interconnected network of brain regions involved in wakeful rest and internal thoughts.

22 Nov 2021

Human lung airway-on-a-chip faithfully recapitulates cystic fibrosis pathology

The inherited progressive disorder cystic fibrosis (CF) causes severe damage to the lungs, and other tissues in the body by affecting the cells that produce mucus, sweat, and digestive juices.

21 Nov 2021

People taking immunosuppressant produce weaker, shorter-lived antibodies after COVID-19 vaccination

People who received two doses of the Pfizer COVID-19 vaccine while on TNF inhibitors - a class of immunosuppressants used to treat rheumatoid arthritis and other autoimmune conditions - generated less powerful and shorter-lived antibodies against the virus that causes COVID-19 than healthy people and those on other kinds of immunosuppressants, according to a study by researchers at Washington University School of Medicine in St. Louis.

21 Nov 2021

Deaf and hard-of-hearing scientists support equity and inclusion in professional societies

Providing some basic standards of support will greatly increase diversity in fields of science and medicine, a group of hard of hearing and deaf scientists argue in a perspective published in the journal Frontiers in Education.

20 Nov 2021

High prevalence of germline variants in Japanese patients with pheochromocytoma and paraganglioma

Certain kinds of tumors can be inherited within families. Identifying the underlying genetic cause is important in treatment, but most studies on these tumors have been carried out on Caucasian populations.

19 Nov 2021

A nasal COVID vaccine using a weakened influenza vector

The authors of a new study, published on the bioRxiv* preprint server, constructed a COVID-19 nasal vaccine candidate by inserting a gene encoding the receptor-binding domain (RBD) of the spike protein of SARS-CoV-2, named CA4-dNS1-nCoV-RBD (dNS1-RBD) in a live attenuated influenza virus (LAIV) vector.

18 Nov 2021

The antiviral function of BET protein against SARS-CoV-2 infection

Considering the past shreds of evidence on BRD2 and BRD4 associated with viral infections, researchers have recently evaluated the function of all relevant BET proteins during COVID-19 infection.

17 Nov 2021

New method to identify potential false-positive COVID-19 results

Researchers from the University of Missouri School of Medicine have developed and tested a process to identify potential false-positive COVID-19 results.

17 Nov 2021

Researchers identify never-before-defined subtypes of a blood cancer

Mount Sinai researchers have developed a new model that uses DNA and RNA sequencing data from hundreds of patients to identify specific genes and genetic alterations responsible for never-before-defined subtypes of a blood cancer called multiple myeloma.

17 Nov 2021

Olympus announces first results of its AI-based pathology diagnostic tool for gastric cancer

The results of Olympus’ ongoing joint research program to create an AI-based pathology diagnostic tool with the potential to streamline pathologists’ workloads were announced at the Japan Society of Digital Pathology Study annual meeting.

From Evident Corporation - Life Sciences 17 Nov 2021

What genes affect the COVID-19 gender imbalance?

Many studies have established that coronavirus disease 2019 (COVID-19) is more infective in men than women, and men are more at risk of severe disease. While some have suggested that behavioral differences could explain increased transmission to men, this does not explain the more morbid prognosis.

16 Nov 2021

Discovery of new receptor that interacts with SARS-CoV-2 spike, suppresses infection

Researchers recently conducted a study to identify host factors affecting cellular interactions of the SARS-CoV-2 spike protein.

16 Nov 2021

Broad neutralization capability of potent nanobody against SARS-CoV-2 variants

A new study has described the molecular basis of the neutralization potency and breadth of nanobodies.

16 Nov 2021

Study offers new insight into the role of tau proteins in ALS pathogenesis

A team led by investigators at Massachusetts General Hospital has shown that people living with amyotrophic lateral sclerosis (ALS), or Lou Gehrig's disease, who carry a mutation in the C9orf72 gene exhibit elevated levels of tau and phosphorylated tau protein in the motor cortex region of the brain.

15 Nov 2021

Common hypertension drug not effective in slowing down the progression of Alzheimer's disease

New research led by the University of Bristol, has shown the drug losartan, normally used to treat high blood pressure (hypertension), is not effective in slowing down the progression of Alzheimer's disease (AD) in people with mild-to-moderate disease after 12 months of treatment.

15 Nov 2021

Researchers discover new gene critical for daily behavioral rhythms

Life is organized on a 24-hour schedule. Central to this regular rhythm is the circadian clock, timekeepers that are present in virtually every organ, tissue and cell type. When a clock goes awry, sleep disruption or a variety of diseases can result.

15 Nov 2021

Potential biomarkers of coagulopathy and disease severity in COVID-19

Scientists have investigated the presence of specific biomarkers in hospitalized COVID-19 patients

15 Nov 2021

Educational program on anticholinergic burden aims to improve health outcomes of older people

Falls, confusion, cognitive decline, dry mouth, constipation and urinary retention. In a new NPS MedicineWise podcast episode released today, Dr Kate Annear, NPS MedicineWise medical adviser and GP talks about the new NPS MedicineWise educational program on the cumulative effects of anticholinergic medicines.

15 Nov 2021

Pathology News and Research

Further Reading

Physical activity may reduce immune cell activation to improve brain health in Alzheimer's disease

Monitoring cellular metabolism for NAFLD/NASH liver disease research

Adolescents with multiple concussions show disruption in the brain's default mode network

Human lung airway-on-a-chip faithfully recapitulates cystic fibrosis pathology

People taking immunosuppressant produce weaker, shorter-lived antibodies after COVID-19 vaccination

Deaf and hard-of-hearing scientists support equity and inclusion in professional societies

High prevalence of germline variants in Japanese patients with pheochromocytoma and paraganglioma

A nasal COVID vaccine using a weakened influenza vector

The antiviral function of BET protein against SARS-CoV-2 infection

New method to identify potential false-positive COVID-19 results

Researchers identify never-before-defined subtypes of a blood cancer

Olympus announces first results of its AI-based pathology diagnostic tool for gastric cancer

What genes affect the COVID-19 gender imbalance?

Discovery of new receptor that interacts with SARS-CoV-2 spike, suppresses infection

Broad neutralization capability of potent nanobody against SARS-CoV-2 variants

Study offers new insight into the role of tau proteins in ALS pathogenesis

Common hypertension drug not effective in slowing down the progression of Alzheimer's disease

Researchers discover new gene critical for daily behavioral rhythms

Potential biomarkers of coagulopathy and disease severity in COVID-19

Educational program on anticholinergic burden aims to improve health outcomes of older people

Industry Focus eBook - Analytical Chemistry (2nd Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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