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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

Mathematics offers new clues in the fight against Alzheimer's

Mathematics may not be the first thing people associate with Alzheimer's disease research. But for Pedro Maia, an assistant professor of mathematics and data science at The University of Texas at Arlington, analyzing how different parts of the brain interact like a network is revealing new insights into one of the world's most devastating brain disorders.

24 Jul 2025

Standard DNA tests miss most cases of NUT carcinoma

The diagnosis of a suspected lung, head, and neck cancer called NUT carcinoma should include additional testing capable of detecting gene fusions that are definitive markers of the disease, according to a study by Dana-Farber Cancer Institute investigators.

24 Jul 2025

Different anti-PD-L1 antibodies show varied results in tumor growth inhibition

Immune checkpoint inhibitors (ICIs), a powerful form of immunotherapy, have revolutionized cancer treatment by unleashing the body's own immune system to fight tumors.

24 Jul 2025

New redox-sensitive pathway reveals how cells activate AMPK in response to metabolic stress

AMP-activated protein kinase (AMPK) plays a central role in maintaining energy balance in cells, especially under energy stress.

24 Jul 2025

AI-driven microscopy predicts and tracks protein aggregation in real time

The accumulation of misfolded proteins in the brain is central to the progression of neurodegenerative diseases like Huntington's, Alzheimer's and Parkinson's.

24 Jul 2025

Scientists discover neuron-like communication system in the gut

In a key advance for regenerative medicine and gut health, scientists from Duke-NUS Medical School and Nanyang Technological University, Singapore (NTU Singapore) have uncovered a precise and unexpected communication system in the gut.

24 Jul 2025

CoVerage outperforms rivals in early detection of COVID mutations

The CoVerage system monitors SARS-CoV-2 evolution, predicting variants and scoring amino acid changes to inform vaccine efficacy and public health strategies.

24 Jul 2025

AI identifies novel gene variants linked to Alzheimer’s risk

This study reveals how machine learning models uncover new genetic variants linked to Alzheimer’s, advancing predictive accuracy in genetic epidemiology.

24 Jul 2025

Gut bacteria send direct signals to the brain to stop you from overeating

Researchers have discovered a novel gut-brain sensory circuit in mice where specialized colonic cells sense bacterial flagellin and rapidly suppress feeding via the vagus nerve. This "neurobiotic sense" operates independently of immune pathways, revealing a direct neural mechanism for microbiota-host communication.

24 Jul 2025

Digging into the past: What ancient proteins say about real medieval meals

Researchers used stable isotope and proteomic analyses on medieval European skeletons to uncover the details of ancient diets. The findings revealed a heavy reliance on C3 plants, terrestrial animal proteins, legumes, and freshwater fish, demonstrating the power of combining methods for paleodietary reconstruction.

24 Jul 2025

Reactivating silent genes offers hope for Rett syndrome treatment

Researchers led by UC Davis Health scientist Sanchita Bhatnagar have developed a promising gene therapy that could treat Rett syndrome.

23 Jul 2025

UN proposal on trans fats could harm nutrition in poor countries, experts warn

A draft UN declaration to eliminate trans-fatty acids from global diets has elicited a sharp reaction from experts who claim it violates the rights of the world's poorest to nutritional benefits of milk and meat.

23 Jul 2025

Research uncovers a 'neurobiotic sense' that lets the brain respond to gut microbe signals

In a breakthrough that reimagines the way the gut and brain communicate, researchers have uncovered what they call a "neurobiotic sense," a newly identified system that lets the brain respond in real time to signals from microbes living in our gut.

23 Jul 2025

Blocking key host pathways may stop Cryptosporidium infections

Researchers at the Francis Crick Institute have mapped the human metabolic pathways that Cryptosporidium, an intestinal parasite, requires to survive.

23 Jul 2025

New method genetically blocks mosquitoes from transmitting malaria

Mosquitoes kill more people each year than any other animal. In 2023, the blood-sucking insects infected a reported 263 million people with malaria, leading to nearly 600,000 deaths, 80% of which were children.

23 Jul 2025

Novel DNA plasmid therapy shows high success rate in treating chronic pain in dogs

Elenagen™, a novel DNA plasmid therapy that previously demonstrated high clinical benefit and low toxicity in cancer patients, has now shown significant promise in alleviating chronic pain demonstrating a 90% success rate.

23 Jul 2025

Intranasal insulin safely and effectively reaches key memory regions of the brain

A groundbreaking brain imaging study from Wake Forest University School of Medicine confirms a vital step toward new Alzheimer's disease treatments: Intranasal insulin, delivered via a simple nasal spray, safely and effectively reaches key memory regions of the brain in older adults.

23 Jul 2025