Antigen News and Research

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Triaptosis could be a promising strategy in the fight against cancer

Cancer remains one of the most critical global public health challenges, exerting profound social, economic, and clinical burdens while limiting gains in human life expectancy.

10 Dec 2025

Sterilized fermented beverage targets obesity and type 2 diabetes pathways in computational study

Researchers profiled a terminally sterilized probiotic-fermented MFH beverage and identified aporphine alkaloids and flavonoids with favorable predicted ADMET properties. Integrated network pharmacology, molecular docking, and 100-ns MD simulations suggest multi-target engagement of metabolic-inflammatory pathways relevant to obesity and type 2 diabetes.

9 Dec 2025

Early RSV infection turns maternal allergy into a powerful driver of childhood asthma

Early-life RSV infection and parental allergy interact to substantially increase childhood asthma risk, supported by population data from more than 1.5 million children and mechanistic mouse experiments. The study shows that viral infection reprograms neonatal immune responses by altering how maternally transferred allergen-specific antibodies are handled, driving long-term allergic airway disease.

8 Dec 2025

Genome-edited immune cell therapy shows promise for treating aggressive blood cancer

A groundbreaking new treatment using genome-edited immune cells, developed by scientists at UCL (University College London) and Great Ormond Street Hospital (GOSH), has shown promising results in helping children and adults fight a rare and aggressive form of blood cancer called T-cell acute lymphoblastic leukemia (T-ALL).

8 Dec 2025

Lymphocyte levels help predict outcomes after CAR T-cell therapy in non-Hodgkin lymphoma

Measuring the lymphocytes - white blood cells that fight infection - in a patient's blood can be used to predict outcomes in non-Hodgkin lymphoma patients who receive CAR T-cell therapy, according to research from physicians at Fox Chase Cancer Center and Temple Health.

8 Dec 2025

Poor dietary iron weakens lung memory T cells after flu infection

Dietary iron deficiency in mice alters lung T cell activation during influenza infection and leads to memory T cells that are present in normal or increased numbers but have impaired antiviral cytokine responses. These functional deficits are most pronounced in lung CD8-positive memory T cells and persist even under optimal recall conditions.

8 Dec 2025

Study uncovers strategy to sensitize estrogen receptor–positive breast tumors to immunotherapy

A study led by researchers at the Hospital del Mar Research Institute advances one of the most significant milestones in breast cancer treatment, making immunotherapy effective against the most common tumor type, estrogen receptor-positive or luminal breast cancer.

4 Dec 2025

Organ-on-a-chip system reveals how aging weakens vaccine-driven anti-cancer immunity

Dr. Vadim Jucaud's lab at the Terasaki Institute has introduced a new organ-on-a-chip platform that recapitulates age-dependent immune responses, offering a more accurate testing bed for evaluating cancer vaccine performance in older adults, the population most affected by cancer and often overlooked in traditional preclinical testing.

4 Dec 2025

Injectable scaffold vaccine shows strong protection against implant-related MRSA

Research reveals that silica scaffolds can train the immune system against S. aureus, offering a novel approach to prevent orthopedic device infections.

4 Dec 2025

Study finds link between Pg-induced periapical disease and systemic metabolic dysfunction

New study examines the oral pathogen Porphyromonas gingivalis (Pg) and suggests its influence may extend beyond dental tissues.

3 Dec 2025

Triaptosis-based therapeutic innovations could offer renewed hope for cancer patients

Cancer remains one of the most critical global public health challenges, exerting profound social, economic, and clinical burdens while limiting gains in human life expectancy.

1 Dec 2025

Breakthrough immunotherapy approved for treatment of adults with aggressive blood cancer

Adult patients with an aggressive form of leukemia will be able to receive a breakthrough immunotherapy, which was invented by UCL researchers, on the NHS within weeks following approval for use by the National Institute for Health and Care Excellence (NICE).

27 Nov 2025

Regenerative medicine offers a pathway toward curing type 1 diabetes

Type 1 diabetes (T1D) is an autoimmune disorder characterized by the specific destruction of insulin-producing pancreatic β-cells.

26 Nov 2025

Scientists uncover how brain enzyme OTULIN controls tau expression

Scientists have uncovered a surprising mechanism by which a brain enzyme called OTULIN controls the expression of tau, the protein that forms toxic tangles in Alzheimer's disease.

25 Nov 2025

Kimchi consumption strengthens antigen recognition and immune regulation

Amid concerns about the simultaneous spread of multiple respiratory diseases, such as colds and influenza, with the change of seasons in current times, a recent clinical study has scientifically proven that kimchi, a traditional Korean fermented food, enhances the function of human immune cells and maintains the balance of the immune system.

24 Nov 2025

Kennedy sharpens vaccine attacks, without scientific backing

As the federal government prepares for the next meeting of its Advisory Committee on Immunization Practices, Health and Human Services Secretary Robert F. Kennedy Jr. has intensified his attacks on aluminum vaccine components used in many shots to boost the body's immune response.

24 Nov 2025

CAR T cell therapy could be a highly effective tool against atherosclerosis

A pioneering preclinical study has shown that CAR T cell therapy-a personalized form of immunotherapy used in cancer treatment-could be a highly effective tool against atherosclerosis, the condition where a build-up of plaque in the arteries reduces blood flow, leading to heart attacks and strokes.

21 Nov 2025

Engineered CAR-T cells show promise against glioblastoma in preclinical models

With a five-year survival rate of less than 5%, glioblastoma is one of the most aggressive types of brain cancer.

20 Nov 2025

Blood group A linked to a higher risk of primary biliary cholangitis

Findings indicate blood group A elevates the risk of primary biliary cholangitis, suggesting ABO group analysis could aid in autoimmune liver disease diagnosis.

19 Nov 2025

Apriori Bio and A*STAR collaborate to develop next-generation saRNA influenza vaccines

Apriori Bio, a Flagship Pioneering company focused on developing prospective, variant-resilient vaccines, and the Agency for Science, Technology and Research Infectious Diseases Labs (A*STAR IDL) announced a strategic research partnership to co-develop and evaluate next generation self-amplifying RNA (saRNA) vaccines targeting seasonal and pandemic influenza.

18 Nov 2025

Antigen News and Research

Triaptosis could be a promising strategy in the fight against cancer

Sterilized fermented beverage targets obesity and type 2 diabetes pathways in computational study

Early RSV infection turns maternal allergy into a powerful driver of childhood asthma

Genome-edited immune cell therapy shows promise for treating aggressive blood cancer

Lymphocyte levels help predict outcomes after CAR T-cell therapy in non-Hodgkin lymphoma

Poor dietary iron weakens lung memory T cells after flu infection

Study uncovers strategy to sensitize estrogen receptor–positive breast tumors to immunotherapy

Organ-on-a-chip system reveals how aging weakens vaccine-driven anti-cancer immunity

Injectable scaffold vaccine shows strong protection against implant-related MRSA

Study finds link between Pg-induced periapical disease and systemic metabolic dysfunction

Triaptosis-based therapeutic innovations could offer renewed hope for cancer patients

Breakthrough immunotherapy approved for treatment of adults with aggressive blood cancer

Regenerative medicine offers a pathway toward curing type 1 diabetes

Scientists uncover how brain enzyme OTULIN controls tau expression

Kimchi consumption strengthens antigen recognition and immune regulation

Kennedy sharpens vaccine attacks, without scientific backing

CAR T cell therapy could be a highly effective tool against atherosclerosis

Engineered CAR-T cells show promise against glioblastoma in preclinical models

Blood group A linked to a higher risk of primary biliary cholangitis

Apriori Bio and A*STAR collaborate to develop next-generation saRNA influenza vaccines

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

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