Proteomics News and Research

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The term 'proteome' was first coined in 1994, and refers to all the proteins in a cell, tissue, or organism. Proteomics refers to the study of the proteome. Because proteins are involved in almost all biological activities, the proteome is a rich source of biological information.

Study sheds new light on p53 tumor suppressor gene's role in ulcerative colitis

Researchers in the lab of Michael Sigal at the Max Delbrück Center and Charité – Universitätsmedizin Berlin have elucidated the role of the p53 gene in ulcerative colitis.

26 Oct 2024

PIONEER software breaks down barriers in protein-protein interaction research

Scientists from Cleveland Clinic and Cornell University have designed a publicly-available software and web database to break down barriers to identifying key protein-protein interactions to treat with medication.

24 Oct 2024

New antibody platform targets evolving viruses

Scientists at the Icahn School of Medicine at Mount Sinai, in collaboration with colleagues in the field, have developed an innovative antibody platform aimed at tackling one of the greatest challenges in treating rapidly evolving viruses like SARS-CoV-2: their ability to mutate and evade existing vaccines and therapies.

23 Oct 2024

P-stalk ribosomes identified as key regulators of immune evasion in cancer

Research uncovers how P-stalk ribosomes regulate cytokine responses, driving immune evasion in tumors across multiple cancer types. It offers new insights into post-translational mechanisms influencing immunotherapy success.

23 Oct 2024

Researchers uncover the potential of JAK inhibitors to treat life-threatening skin disease

Researchers identified Janus kinase inhibitors as a promising treatment for the severe drug-induced skin condition toxic epidermal necrolysis, by analyzing patient biopsies with deep visual proteomics.

17 Oct 2024

New grant aims to develop rapid biosensors for detecting African swine fever

Foreign animal diseases are a global threat to swine production with the potential for detrimental economic implications.

17 Oct 2024

Groundbreaking discovery offers hope for patients suffering from toxic epidermal necrolysis

A global team of researchers at the Max Planck Institute of Biochemistry has made a groundbreaking discovery that saves the lives of patients suffering from toxic epidermal necrolysis.

16 Oct 2024

New drug targets identified for retinitis pigmentosa therapies

An international team of researchers has identified new drug targets for therapies that could benefit patients with different forms of retinitis pigmentosa and other inherited retinal diseases.

16 Oct 2024

De novo antibody protein sequencing reveals novel functional and neutralizing antibodies post-SARS-CoV-2 vaccination

Rapid Novor has published a study that highlights the power of combining de novo antibody protein sequencing with conventional proteomics to uncover functional and neutralizing antibodies in human plasma following SARS-CoV-2 vaccination.

From Rapid Novor Inc 14 Oct 2024

Computational tools unlock the secrets of the genome

In collaboration with the International Conference on Research in Computational Molecular Biology (RECOMB), Genome Research publishes a collection of 20 computational methods and their applications in genomics including spatial, single-cell, and long-read sequencing.

13 Oct 2024

Study uncovers mechanism of MX protein in fighting HIV-1 and herpes simplex virus

A group of researchers led by Xavier Saelens and Sven Eyckerman at the VIB-UGent Center for Medical Biotechnology discovered how a protein linked to the human immune system wards off HIV-1 and herpes simplex virus-1 by assembling structures in the cell that lure in these viruses and then trap them or even take them apart.

9 Oct 2024

Bruker Introduces Innovative Neuroscience Research Solution with High-Speed OptoVolt Voltage Imaging

New multiphoton microscopy module enables millisecond neural event imaging at single neuron resolution.

From Bruker Nano Surfaces and Metrology 7 Oct 2024

Study uncovers biological drivers of plasma proteins, offering new insights for disease biomarkers and drug discovery

Researchers mapped the biological influences on 4,775 plasma proteins, revealing the interplay of modifiable and non-modifiable factors, with key implications for disease biomarkers and drug targets.

30 Sep 2024

Study uncovers hidden proteins fueling heart disease and stroke

Researchers identified key proteins linked to cardiovascular disease, highlighting new targets for drug development using genetic and observational analyses in UK and China biobanks.

26 Sep 2024

Drug effects on gut microbiome altered by bacterial communities

Many human medications can directly inhibit the growth and alter the function of the bacteria that constitute our gut microbiome.

24 Sep 2024

Groundbreaking project seeks to illuminate the complexities of Parkinson's

Launching today, Landmark is a groundbreaking three-year research programme that aims to understand Parkinson’s in unprecedented detail. The project brings together Parkinson’s UK, Imperial College London, GSK, Novartis, Roche and UCB for the first time, and has been made possible by a founding gift of £4 million from the Gatsby charitable foundation.

24 Sep 2024

Philanthropic investment establishes research center to advance precision diagnosis for diseases

An outstanding $21 million philanthropic investment will establish a pioneering research center to advance precision diagnosis for diseases that affect millions of Australians.

19 Sep 2024

Researchers discover how oral cancer cells may block the body's immune response

Macquarie University researchers have discovered new information about how oral cancer cells may block the body's immune response. This could lead to better treatments for this aggressive disease.

18 Sep 2024

New insights into the mechanisms of efavirenz-induced neurotoxicity

Efavirenz is an important drug for treating HIV infection, but it has negative effects that can significantly impact patients' quality of life over time. It causes neuropsychiatric disorders and neurocognitive impairment in roughly 50 percent of patients. The drug is associated with abnormal lipid levels in blood plasma, but the molecular mechanisms responsible for negative clinical observations are unknown.

18 Sep 2024

Microbial-immune interactions in severe asthma: Insights into pathogen dominance and treatment approaches

Researchers assess the airway microbiome and host immune-inflammatory responses to identify treatable aspects of severe asthma.

17 Sep 2024

Proteomics News and Research

Further Reading

Study sheds new light on p53 tumor suppressor gene's role in ulcerative colitis

PIONEER software breaks down barriers in protein-protein interaction research

New antibody platform targets evolving viruses

P-stalk ribosomes identified as key regulators of immune evasion in cancer

Researchers uncover the potential of JAK inhibitors to treat life-threatening skin disease

New grant aims to develop rapid biosensors for detecting African swine fever

Groundbreaking discovery offers hope for patients suffering from toxic epidermal necrolysis

New drug targets identified for retinitis pigmentosa therapies

De novo antibody protein sequencing reveals novel functional and neutralizing antibodies post-SARS-CoV-2 vaccination

Computational tools unlock the secrets of the genome

Study uncovers mechanism of MX protein in fighting HIV-1 and herpes simplex virus

Bruker Introduces Innovative Neuroscience Research Solution with High-Speed OptoVolt Voltage Imaging

Study uncovers biological drivers of plasma proteins, offering new insights for disease biomarkers and drug discovery

Study uncovers hidden proteins fueling heart disease and stroke

Drug effects on gut microbiome altered by bacterial communities

Groundbreaking project seeks to illuminate the complexities of Parkinson's

Philanthropic investment establishes research center to advance precision diagnosis for diseases

Researchers discover how oral cancer cells may block the body's immune response

New insights into the mechanisms of efavirenz-induced neurotoxicity

Microbial-immune interactions in severe asthma: Insights into pathogen dominance and treatment approaches

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