Human physiology is the science of the mechanical, physical, and biochemical functions of humans in good health, their organs, and the cells of which they are composed. The principal level of focus of physiology is at the level of organs and systems. Most aspects of human physiology are closely homologous to corresponding aspects of animal physiology, and animal experimentation has provided much of the foundation of physiological knowledge. Anatomy and physiology are closely related fields of study: anatomy, the study of form, and physiology, the study of function, are intrinsically tied and are studied in tandem as part of a medical curriculum.
A team led by scientists at the University of Pennsylvania and University of Georgia provides thousands of researchers around the world with access to the Eukaryotic Pathogen Genomics Database (EuPathDB.org), a collection of resources for analyzing large-scale datasets associated with microbial pathogens.
A study from McMaster University has found a potential mechanism explaining why some people who take drugs to lower their cholesterol develop sore, aching muscles.
A global panel of exercise oncology experts today published new guidance recommending the systematic use of an “exercise prescription” to help cancer patients cope with treatment side effects and lower the risk of developing certain cancers.
When the adrenal gland produces too much aldosterone, this often leads to high blood pressure and kidney damage (hyperaldosteronism). It has only recently emerged that several patients harbor a mutation in the gene for the ClC-2 chloride channel.
Pediatric anesthesiologists, like Dr. Guelay Bilen-Rosas at UW Health, have long been concerned by how difficult it is to detect breathing problems among young patients during anesthesia.
When trying to get pregnant, couples often change their lifestyles, going on crash diets or taking up stricter exercise regimens. New research, done on mice, suggests that men might be best off avoiding crash diets, as it may affect the heart health of their offspring.
The waning effectiveness of drugs over time continues to be a major challenge in treating diseases, including asthma.
Due to strain-specific behavioral idiosyncrasies, inbred mouse strains are suboptimal research models for behavioral aging studies.
For all the attention the human microbiome has been getting over the last few years, one aspect of such research rarely makes headlines: the difficulty of observing how it changes over time in response to various stimuli.
New research suggests a vaccine that blocks a digestive hormone may slow the spread of pancreatic cancer, potentially increasing survival rates. The study, published ahead of print in the American Journal of Physiology—Gastrointestinal and Liver Physiology, was chosen as an APSselect article for October.
Aging is an inevitable and a normal process of life. As people grow older, they lose muscle mass caused by age-related sarcopenia. In older adults, the maintenance of muscle mass and strength contribute to mobility which impacts quality of life. One of the reasons why older adults become frail is because of age-related muscle weakness.
A study recently published by researchers from the Ohio Musculoskeletal and Neurological Institute at the Ohio University Heritage College of Osteopathic Medicine, in collaboration with a colleague from outside Ohio University, finds new evidence to support the belief that the nervous system plays an important role in age-related weakness.
If you thought a glass or two of alcohol on special occasions was safe during pregnancy, think again. Research in The Journal of Physiology shows even small amounts of alcohol consumed during pregnancy can cause insulin-resistance, which increases the likelihood of diabetes, in male rat offspring.
The need to feel balanced drives the development of coordination between body and limbs as zebrafish larvae learn to swim, a new study by NYU School of Medicine finds.
It has long been known that obesity impairs our metabolism and predisposes to diabetes and heart disease. New research in The Journal of Physiology has shown that the effects of maternal obesity even pass across generations to offspring, accelerating the rate of aging of metabolic problems that occur in normal life.
A new Northwestern University study finds that despite human's close genetic relationship to apes, the human gut microbiome is more similar to that of Old World monkeys like baboons than to that of apes like chimpanzees.
Blocking the mineralocorticoid receptor (MR)- a protein that helps maintain normal levels of salt and water in the body- in immune cells may help reduce the risk of heart attack and stroke by improving blood vessel health.
A research team from Carnegie Mellon University and Yale University will advance their innovative, synthetic nucleic acid-based gene editing technique under a new grant from the National Institutes of Health's Somatic Cell Genome Editing Program.
University of California, Irvine researcher Kevin Beier, PhD, assistant professor of physiology and biophysics in the School of Medicine, received a 2019 NIH Director's New Innovator Award to study learning and memory in an effort to discover new treatments for behavioral symptoms of chronic stress and depression.
Ever since three US-based researchers working independently unveiled the role of nitric oxide in mediating blood vessel dilation, endothelial cell contraction and smooth muscle relaxation, their discoveries have served as a basis for novel treatments for high blood pressure and erectile dysfunction, among other conditions.
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