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Hormones may drive the differences in opioid misuse between men and women

The opioid epidemic has claimed more than half a million lives in the U.S. since 1999, about three-quarters of them men, according to the National Institutes of Health.

10 Mar 2025

Stress and obesity found to fuel early pancreatic cancer growth

A new study led by UCLA investigators suggests that chronic stress and an unhealthy diet may work together to fuel the early development of pancreatic cancer, shedding light on how lifestyle factors contribute to one of the deadliest malignancies.

10 Mar 2025

Breakthrough drug combination targets KRAS mutation in lung cancer

A breakthrough in lung cancer treatment may be on the horizon. Scientists at VCU Massey Comprehensive Cancer Center have uncovered a powerful combination therapy leveraging sotorasib-an FDA-approved drug in the market-and an experimental drug called FGTI-2734, which could make precision medicine more effective for patients with a highly resistant form of lung cancer.

10 Mar 2025

British scientists unveil world-leading technology to speed up drug discovery

A new 3D bio-printer that produces human-like tissue holds the potential to revolutionize the discovery of new drugs for cancer, heart disease and arthritis.

10 Mar 2025

How the FDA lets chemicals pour into America’s food supply

Joseph Shea, who sells athletic wear in Myrtle Beach, South Carolina, wonders and worries about the food he eats.

10 Mar 2025

GLP-1 drugs may cut risk of leukemia and lymphoma in type 2 diabetes patients

Researchers found that GLP-1 receptor agonists (GLP-1RAs) significantly reduce the risk of several blood cancers in type 2 diabetes patients, especially compared to insulin. The study also highlights GLP-1RAs’ potential as a cancer-protective treatment, independent of glucose control.

9 Mar 2025

Can microbiome discoveries finally become treatments? Scientists show the way

Researchers propose a novel iterative strategy combining big data and experimental models to move microbiome research from theory to clinical applications. The study highlights the need to bridge the gap between correlation and causation to develop effective microbiome-based therapies.

9 Mar 2025

Long-term NSAID use may lower dementia risk

Long-term NSAID use reduces dementia risk, particularly in those without the APOE-ε4 gene, highlighting the importance of sustained anti-inflammatory treatment over dosage levels.

9 Mar 2025

Fentanyl poisonings among children in the U.S. increase sharply over eight years

Incidents of children in the U.S. being poisoned by the synthetic opioid fentanyl "increased and became more severe", a new study reveals.

8 Mar 2025

Ubiquitination plays a key role in cancer stem cell function and treatment resistance

This review highlights the critical role of ubiquitination in governing the functionality of cancer stem cells (CSCs), shedding light on potential therapeutic targets for combating tumor progression, recurrence, and drug resistance.

8 Mar 2025

Existing drug could prevent liver damage caused by ammonia build-up

High levels of ammonia kill liver cells by damaging the mitochondria that power the cells. But this can be prevented using an existing drug due to start clinical trials, finds a new study in mice led by researchers from UCL.

7 Mar 2025

Eradivir begins Phase 2 challenge study for antiviral therapeutic EV25

Eradivir, a clinical-stage small molecule immunotherapy biotech company, announced it has begun a Phase 2 challenge study with its antiviral therapeutic, EV25. The study will provide safety and efficacy data gathered from otherwise healthy participants infected with influenza then later treated with EV25.

7 Mar 2025

Insilico Medicine's AI-driven drug Rentosertib receives official generic name

Insilico Medicine("Insilico"), a clinical stage generative artificial intelligence (AI)-driven biotechnology company, recently announced that its breakthrough drug candidate for idiopathic pulmonary fibrosis (IPF) – Rentosertib (formerly known as ISM001-055) – has been granted an official generic name by the United States Adopted Names (USAN) Council.

7 Mar 2025

Research poses a new explanation for how cancer-fighting drugs attack and destroy tumor cells

Research by UMass Chan Medical School scientists Sharon Cantor, PhD, and Jenna M. Whalen, PhD, poses a new explanation for how cancer-fighting drugs attack and destroy BRCA1 and BRCA2 tumor cells.

7 Mar 2025

Research reveals genetic connection between obesity in dogs and humans

Researchers studying British Labrador retrievers have identified multiple genes associated with canine obesity and shown that these genes are also associated with obesity in humans.

6 Mar 2025

New clinical trial aims to optimize pain management and reduce opioid use after mastectomy

A multidisciplinary team of University of Cincinnati Cancer Center researchers is leading a new clinical trial aimed to optimize pain management and reduce the need for opioids after mastectomy procedures.

6 Mar 2025

Researchers discover why scleroderma affects women more than men

Two new studies led by researchers at Hospital for Special Surgery (HSS) have uncovered key biological mechanisms driving systemic sclerosis (SSc), or scleroderma – a rare and often devastating autoimmune disease that causes fibrosis (tissue hardening) and inflammation.

6 Mar 2025