Alzheimer's Disease News and Research

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Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. In most people with AD, symptoms first appear after age 60. AD is the most common cause of dementia among older people, but it is not a normal part of aging. Dementia refers to a decline in cognitive function that interferes with daily life and activities. AD starts in a region of the brain that affects recent memory, then gradually spreads to other parts of the brain. Although treatment can slow the progression of AD and help manage its symptoms in some people, currently there is no cure for this devastating disease.

Study lays the groundwork for developing novel strategies to treat neurological diseases

A research team from the School of Life Sciences at The Chinese University of Hong Kong has recently discovered that SOX9 protein is an essential regulatory factor of choroid plexus function that ensures the correct composition of cerebrospinal fluid (CSF).

24 Feb 2021

New platform can help treat neurodegenerative diseases through regenerative medicine

Imagine if surgeons could transplant healthy neurons into patients living with neurodegenerative diseases or brain and spinal cord injuries.

24 Feb 2021

HIV-positive people with severe immunosuppression, APOE4 gene may have increased risk for dementia

People living with the human immunodeficiency virus (HIV) who have a history of severe immunosuppression and at least one copy of the Alzheimer's disease-related gene variant APOE4, might see a compounded adverse effect on the circuitry that impacts memory.

22 Feb 2021

Researchers discover first evidence of protein folding driven by liquid-liquid phase separation

Scientists have discovered the first evidence of protein folding driven by liquid-liquid phase separation, a phenomenon in which fluids form into microscopic droplets and separate inside cells -- like drops of oil in water.

20 Feb 2021

Report proposes new system of universal coverage to support long-term care of older Americans

The COVID-19 pandemic's heavy toll on older Americans highlights the need to strengthen the nation's safety net for people in need of long-term services and supports, an Oregon Health & Science University researcher and co-authors argue in a new report published by Milbank Quarterly.

19 Feb 2021

Understanding the dynamics of brain blood flow could hold key for treating neurologic conditions

While the human brain has over 400 miles of total vasculature, little is known about the tiny capillaries that make up much of this intricate labyrinth of blood vessels critical for delivering oxygenated blood and nutrients to billions of brain cells.

19 Feb 2021

Henry Ford first in the U.S. to offer FDA-approved DBS system to treat Parkinson's disease

The Parkinson's Disease and Movement Disorder Center at Henry Ford Health System was the first in the United States to offer a new FDA-approved device to help treat the symptoms of Parkinson's disease.

18 Feb 2021

UC San Diego researchers launch clinical trial to test gene therapy for Alzheimer’s disease

Researchers at University of California San Diego School of Medicine have launched a first-in-human Phase I clinical trial to assess the safety and efficacy of a gene therapy to deliver a key protein into the brains of persons with Alzheimer's disease (AD) or Mild Cognitive Impairment (MCI), a condition that often precedes full-blown dementia.

18 Feb 2021

Modified therapeutic molecule enhances stroke treatment

A research team from the Institut national de la recherche scientifique (INRS) has improved the protective effect of a molecule against ischemic stroke, which is caused by an interruption of blood flow to the brain.

18 Feb 2021

Study examines postoperative outcomes of coronary revascularization in people with and without Alzheimer’s

The risk of both mortality and rehospitalisation after an elective revascularisation procedure for coronary artery disease is similar for people with and without Alzheimer’s disease (AD), but people with AD had worse outcomes after an emergency procedure, according to a new study from the University of Eastern Finland.

18 Feb 2021

Researchers identify antibody that removes amyloid plaques without the risk of brain bleeds

As people age, a normal brain protein known as amyloid beta often starts to collect into harmful amyloid plaques in the brain. Such plaques can be the first step on the path to Alzheimer's dementia.

18 Feb 2021

Study: Patients should be assessed for frailty before considering multiple surgeries

Patients should be assessed for frailty before having many types of surgery, even if the surgery is considered low risk, a review of two national patient databases shows.

18 Feb 2021

Scientists reveal the shape of glutamate transporter in human cells

A University of Sydney-led international team of scientists has revealed the shape of one of the most important molecular machines in our cells the glutamate transporter, helping to explain how our brain cells communicate with one another.

18 Feb 2021

Study: Cognitive SuperAgers resist protein tangles that lead to Alzheimer’s disease

A new Northwestern Medicine study showed cognitive SuperAgers have resistance to the development of fibrous tangles in a brain region related to memory and which are known to be markers of Alzheimer's disease.

17 Feb 2021

New study sheds light on potential pathophysiological mechanism underlying delirium

Delirium, a common syndrome among older adults, particularly in those who have recently undergone surgery, critically ill patients in the ICU, and in older patients with multiple health issues, is a form of acute confusion that is characterized by poor attention, disorientation, impaired memory, delusions, and abrupt changes in mood and behavior.

17 Feb 2021

Lewy body dementia may share similar genetic profiles with Alzheimer's disease

In a study led by National Institutes of Health (NIH) researchers, scientists found that five genes may play a critical role in determining whether a person will suffer from Lewy body dementia, a devastating disorder that riddles the brain with clumps of abnormal protein deposits called Lewy bodies.

17 Feb 2021

Study: Alzheimer's patients have worse outcomes after elective revascularization procedure

The risk of both mortality and rehospitalization after an elective revascularization procedure for coronary artery disease is similar for people with and without Alzheimer's disease (AD), but people with AD had worse outcomes after an emergency procedure, according to a new study from the University of Eastern Finland.

17 Feb 2021

Alzheimer's Disease News and Research

Further Reading

Study lays the groundwork for developing novel strategies to treat neurological diseases

New platform can help treat neurodegenerative diseases through regenerative medicine

HIV-positive people with severe immunosuppression, APOE4 gene may have increased risk for dementia

Researchers discover first evidence of protein folding driven by liquid-liquid phase separation

Report proposes new system of universal coverage to support long-term care of older Americans

Understanding the dynamics of brain blood flow could hold key for treating neurologic conditions

Henry Ford first in the U.S. to offer FDA-approved DBS system to treat Parkinson's disease

UC San Diego researchers launch clinical trial to test gene therapy for Alzheimer’s disease

Modified therapeutic molecule enhances stroke treatment

Study examines postoperative outcomes of coronary revascularization in people with and without Alzheimer’s

Researchers identify antibody that removes amyloid plaques without the risk of brain bleeds

Study: Patients should be assessed for frailty before considering multiple surgeries

Scientists reveal the shape of glutamate transporter in human cells

Study: Cognitive SuperAgers resist protein tangles that lead to Alzheimer’s disease

New study sheds light on potential pathophysiological mechanism underlying delirium

Lewy body dementia may share similar genetic profiles with Alzheimer's disease

Study: Alzheimer's patients have worse outcomes after elective revascularization procedure

Simulating an overactive autoimmune response leads to changes in the brain region

Gait variability could help diagnose different types of dementia, Alzheimer's disease

Major antioxidant in green tea may increase levels of natural anti-cancer protein

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