Oxygen News and Research

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Could a fungus-derived compound reduce hyperinflammation in severe COVID-19?

New research from scientists at the University of Pennsylvania, USA, demonstrates that cyclosporine A (CSA), a calcineurin inhibitor that modulates cytokine production, may have potential antiviral properties against coronaviruses.

18 Jun 2021

Fighting the good fight –a new protein found in red blood cells linked to limiting cognitive decline

A new study shows that depleting mouse blood of the protein ADORA2B led to faster declines in memory, and increased brain inflammation.

18 Jun 2021

Regeneron mAb cocktail benefits hospitalized patients with no natural SARS-CoV-2 antibody response

Researchers reporting on findings from the Randomized Evaluation of COVID-19 Therapy (RECOVERY) trial in the UK are recommending that any therapeutic use of REGEN-COV may be best restricted to individuals without detectable antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

17 Jun 2021

New mouse model mimics human pathology of childhood restrictive cardiomyopathy

Severe childhood restrictive cardiomyopathy is a condition that causes the muscles in the walls of the heart to become stiff, so that the heart is unable to fill properly with blood.

17 Jun 2021

ACT Accelerator partnership welcomes commitment of 870 million vaccine doses, highlights funding gaps

At the close of this year’s G7 Leaders’ summit, the Prime Minister of the United Kingdom of Great Britain and Northern Ireland announced a donation of an additional 870 million vaccine doses from attendees, with the majority to be delivered through COVAX, the vaccines pillar of the Access to COVID 19 Tools Accelerator, within the next year.

15 Jun 2021

Treatment-resistant depression relieved by laughing gas

Researchers at the Washington University School of Medicine in St. Louis and the University of Chicago have found that a single, one-hour treatment involving the inhalation of a mixture of oxygen and the anesthetic drug nitrous oxide, also known as laughing gas, can improve symptoms of depression in people resistant to treatment.

15 Jun 2021

High genetic running capacity promotes healthier metabolism in tissues as we age

High running capacity is associated with health and longevity. However, whether high genetic running capacity promotes more efficient metabolism with aging is not known.

14 Jun 2021

COVID-19 PCR tests can withstand freeze-drying process

In fighting the COVID-19 pandemic, it's not just the vaccines that require complicated cold supply chains and refrigerated storage. Polymerase chain reaction (PCR) tests -- often considered the "gold standard" of testing -- also have enzymes and reagents that need to be frozen.

14 Jun 2021

Researchers demonstrate an alternative way to produce highly detailed images of the brain

The gold standard in functional brain imaging for over two decades, functional magnetic resonance imaging (fMRI) has transformed the landscape of research and clinical care. Yet, because of its cost and functional limitations, scientists have continued to look for new ways to see into the human brain.

14 Jun 2021

Nanoparticle-based therapy alleviates pulmonary hypertension in mouse model of rare lung disease

The disease is so rare and complex that its acronym is hard to pronounce. But for infants unlucky enough to be born with this lung disease, the outcome is usually fatal.

14 Jun 2021

New mathematical model helps simulate progression of age-related macular degeneration

Researchers from the Universidad Carlos III de Madrid (UC3M) have created a mathematical model and simulated numerically the progression of age-related macular degeneration, one of the main causes of blindness.

14 Jun 2021

Study suggests COVID-19 in children is milder than the flu

Researchers retrospectively analyzed the medical records of children in Turkey hospitalized because of coronavirus disease 2019 (COVID-19) or influenza and found COVID-19 to be milder than influenza in this group.

14 Jun 2021

Metformin prevents pulmonary or lung inflammation in animals infected with SARS-CoV-2

Metformin is a widely prescribed blood sugar-lowering drug. It is often used as an early therapy (in combination with diet and lifestyle changes) for type 2 diabetes, which afflicts more than 34 million Americans.

11 Jun 2021

Cross-sectional study explores differences in biomarkers in fulminant and non-fulminant COVID-19 myocarditis

Researchers from the US recently conducted a study to examine the clinical course and echocardiographic and lab testing across clinically defined fulminant and non-fulminant COVID-19 myocarditis. This study is published on the preprint server, medRxiv.*

11 Jun 2021

Major anti-cancer protein released by neutrophils selectively kills tumor cells

A study published in the June 10, 2021 issue of Cell describes a remarkable new mechanism by which the body's own immune system can eliminate cancer cells without damaging host cells.

10 Jun 2021

New device can provide improved protection to newborns on ventilators

If a newborn is moved or becomes agitated while on a ventilator, the breathing tube also could move. Just a few seconds with the tube in the wrong position might lead to a critical lack of oxygen to the brain, possibly resulting in lifelong disability or brain damage or even ending the baby's life.

10 Jun 2021

Microgel-coated mesenchymal stromal cells can reverse pulmonary fibrosis

Researchers at the University of Illinois Chicago have shown that even after lung tissue has been damaged, it may be possible to reverse fibrosis and promote tissue repair through treatment with microgel-coated mesenchymal stromal cells.

9 Jun 2021

Testing placental hormone levels can help identify candidates for pregnancy complications

Women who will develop potentially life-threatening disorders during pregnancy can be identified early when hormone levels in the placenta are tested, a new study has shown.

8 Jun 2021

ONK Therapeutics and Trinity researchers seek to improve cellular therapies for treating cancer

ONK Therapeutics Ltd, an innovative natural killer (NK) cell therapy company, today announced that it has been awarded an Innovation Partnership Programme grant by Enterprise Ireland (EI) to fund collaborative research at Trinity College Dublin, Ireland, led by Dr. David Finlay to optimize the metabolism and engineering of NK cells for improved cancer therapies.

8 Jun 2021

Boeing tested air purifiers like those widely used in schools. It decided not to use them in planes.

Aerospace giant Boeing tested two kinds of ionization technologies — like those widely adopted in schools hoping to combat covid — to determine how well each killed germs on surfaces and decided that neither was effective enough to install on its commercial planes.

8 Jun 2021

Oxygen News and Research

Could a fungus-derived compound reduce hyperinflammation in severe COVID-19?

Fighting the good fight –a new protein found in red blood cells linked to limiting cognitive decline

Regeneron mAb cocktail benefits hospitalized patients with no natural SARS-CoV-2 antibody response

New mouse model mimics human pathology of childhood restrictive cardiomyopathy

ACT Accelerator partnership welcomes commitment of 870 million vaccine doses, highlights funding gaps

Treatment-resistant depression relieved by laughing gas

High genetic running capacity promotes healthier metabolism in tissues as we age

COVID-19 PCR tests can withstand freeze-drying process

Researchers demonstrate an alternative way to produce highly detailed images of the brain

Nanoparticle-based therapy alleviates pulmonary hypertension in mouse model of rare lung disease

New mathematical model helps simulate progression of age-related macular degeneration

Study suggests COVID-19 in children is milder than the flu

Metformin prevents pulmonary or lung inflammation in animals infected with SARS-CoV-2

Cross-sectional study explores differences in biomarkers in fulminant and non-fulminant COVID-19 myocarditis

Major anti-cancer protein released by neutrophils selectively kills tumor cells

New device can provide improved protection to newborns on ventilators

Microgel-coated mesenchymal stromal cells can reverse pulmonary fibrosis

Testing placental hormone levels can help identify candidates for pregnancy complications

ONK Therapeutics and Trinity researchers seek to improve cellular therapies for treating cancer

Boeing tested air purifiers like those widely used in schools. It decided not to use them in planes.

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