Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Immunotherapy treatment may be appropriate for patients with earlier stages of melanoma

An immunotherapy called pembrolizumab reduced cancer recurrence after surgery in patients with stage IIb and IIc melanoma, according to the results of an international, randomized phase III clinical trial led by UPMC Hillman Cancer Center.

20 Sep 2021

A new synthetic multiantigen MVA vaccine COH04S1 effective against SARS-CoV-2

A new study utilized MVA to develop vaccine candidates that were subsequently evaluated in animal models of congenital cytomegalovirus disease.

19 Sep 2021

Unique imaging technique sheds light on how cells related to IBD affect intestinal tissues

New "maps" of hundreds of thousands of cells related to inflammatory bowel disease shed greater light on their effects on intestinal tissues through a newly utilized imaging technique called "imaging mass cytometry."

16 Sep 2021

Albert Einstein College of Medicine receives $5 million NIH grant for IDD research

Albert Einstein College of Medicine has received a five-year, $5 million grant from the National Institutes of Health to support the Rose F. Kennedy Intellectual and Developmental Disabilities Research Center, which has been at the forefront of research on normal and abnormal brain development for more than 50 years.

15 Sep 2021

NIH awards funding to build a national study population of volunteers on long-term effects of COVID-19

The National Institutes of Health awarded nearly $470 million to build a national study population of diverse research volunteers and support large-scale studies on the long-term effects of COVID-19.

15 Sep 2021

Single protein is a key player in two very common forms of dementia, study reveals

Dementia has many faces, and because of the wide range of ways in which it can develop and affect patients, it can be very challenging to treat.

15 Sep 2021

Study on B lymphocytes may contribute to the optimization of vaccines

Our bodies can fine-tune the immune response to an infection and make it proportional to the threat at hand.

15 Sep 2021

A sweet pill to swallow: oral nucleoside analog of Remdesivir improved SARS-CoV-2 pathogenesis in mice

A new study focused on in vitro antiviral activity in various cell models and in vivo therapeutic efficacy of oral GS-621763 in a mouse model of SARS-CoV-2 pathogenesis.

15 Sep 2021

Severe COVID-19 linked to increase in autoantibodies

Hospitalized COVID-19 patients are substantially more likely to harbor autoantibodies - antibodies directed at their own tissues or at substances their immune cells secrete into the blood - than people without COVID-19, according to a new study.

14 Sep 2021

Metabolic and immune markers as tools for risk stratification and monitoring in COVID-19

In a new study posted to the medRxiv* server scientists from Weil Cornell University and Stony Brook University in New York attempted to identify the metabolic and immune markers associated with severe COVID-19 disease using high-throughput targeted nuclear magnetic resonance (NMR) spectroscopy and high-dimensional flow cytometry. This will facilitate risk stratification, monitoring, and therapeutic interventions in COVID-19 patients.

14 Sep 2021

COVID-19 lockdown linked to improved glycemic control in type 1 diabetes

A new study looks at changes in the glycemic control in patients with diabetes during the lockdowns implemented to deal with the COVID-19 pandemic.

13 Sep 2021

Novel method enables 3D imaging of human organs with micrometer precision

Researchers at Umeå University, Sweden, now demonstrate a method by which specific cell types in human organs can be studied with micrometer precision.

13 Sep 2021

Study finds possible direct connection between neurodegenerative diseases and the herpesvirus

A new study by researchers at University of Illinois Chicago suggests that when the protein optineurin, or OPTN, is present in cells it restricts the spread of HSV-1, the herpes simplex virus type 1.

13 Sep 2021

Neutrophil extracellular traps boost the bacterial killing power of macrophages

Like a spider trapping its prey, our immune system cells cooperate to capture and "eat" bacteria.

12 Sep 2021

The strengths and weaknesses of the spike protein in SARS-CoV-2 variants

The S protein has the ability to appropriate various conformations that are dependent on the formation of the receptor-binding domain (RBD) of its protomers.

12 Sep 2021

Survey: Less than half of community oncologists use biomarker testing to guide lung cancer care

Less than half of community oncologists surveyed indicated that they use biomarker testing to guide patient discussions compared to 73% of academic clinicians, according to a report issued today at the IASLC 2021 World Conference on Lung Cancer.

12 Sep 2021

Microscopy paired with AI leads to a fast, accurate, and cost-effective COVID-19 test

Beckman researchers paired microscopy with artificial intelligence to develop a COVID-19 test that's fast, accurate, and cost-effective. All we need to do is say "ahh."

12 Sep 2021

First rat model recapitulates all disabling alterations experienced by patients with Morquio A disease

A research team from the Universitat Autònoma de Barcelona has generated the first rat model recapitulating all disabling alterations experienced by patients with Mucopolysaccharidosis type IVA, also known as Morquio A disease.

12 Sep 2021

Duke/UNC awarded NIH funding to establish prestigious Alzheimer's Disease Research Center

Duke University and the University of North Carolina at Chapel Hill have been awarded funds from the National Institutes of Health to establish a prestigious Alzheimer's Disease Research Center (ADRC), part of a federally-funded national network of similar centers.

9 Sep 2021

Allergic reactions provide protection against yeast-triggered asthma, research shows

We think of asthma and other allergic diseases as unnecessary aberrant immune responses that do more harm than good. However, new evidence by an international team led by researchers at Baylor College of Medicine shows that some allergic reactions provide necessary protection against highly invasive and potentially lethal infectious agents, such as yeast.

9 Sep 2021

Pathology News and Research

Further Reading

Immunotherapy treatment may be appropriate for patients with earlier stages of melanoma

A new synthetic multiantigen MVA vaccine COH04S1 effective against SARS-CoV-2

Unique imaging technique sheds light on how cells related to IBD affect intestinal tissues

Albert Einstein College of Medicine receives $5 million NIH grant for IDD research

NIH awards funding to build a national study population of volunteers on long-term effects of COVID-19

Single protein is a key player in two very common forms of dementia, study reveals

Study on B lymphocytes may contribute to the optimization of vaccines

A sweet pill to swallow: oral nucleoside analog of Remdesivir improved SARS-CoV-2 pathogenesis in mice

Severe COVID-19 linked to increase in autoantibodies

Metabolic and immune markers as tools for risk stratification and monitoring in COVID-19

COVID-19 lockdown linked to improved glycemic control in type 1 diabetes

Novel method enables 3D imaging of human organs with micrometer precision

Study finds possible direct connection between neurodegenerative diseases and the herpesvirus

Neutrophil extracellular traps boost the bacterial killing power of macrophages

The strengths and weaknesses of the spike protein in SARS-CoV-2 variants

Survey: Less than half of community oncologists use biomarker testing to guide lung cancer care

Microscopy paired with AI leads to a fast, accurate, and cost-effective COVID-19 test

First rat model recapitulates all disabling alterations experienced by patients with Morquio A disease

Duke/UNC awarded NIH funding to establish prestigious Alzheimer's Disease Research Center

Allergic reactions provide protection against yeast-triggered asthma, research shows

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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