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Molecular probes can track the progress of protein that misbehaves in neurodegenerative diseases

A team of researchers from the IIT-Istituto Italiano di Tecnologia (Italian Institute of Technology) has designed in silico "molecular probes" able to track the progress of a protein that misbehaves in different neurodegenerative diseases, such as Amyotrophic Lateral Sclerosis (ALS) and Fronto-Temporal Dementia (FTD).

9 Sep 2022

Researchers produce high-resolution crystal structure of enzyme critical to SARS-CoV-2 survival

A team of Mount Sinai researchers has produced a high-resolution crystal structure of an enzyme essential to the survival of SARS-CoV-2, the virus that causes COVID-19.

9 Sep 2022

Researchers review role of melatonin in pregnancies complicated by placental insufficiency

A new study explores the role of melatonin in pregnancy.

8 Sep 2022

Study provides a potential game-changer in assessing treatment response in pancreatic cancer patients

The statistics for pancreatic cancer are sobering. With a five-year survival rate of only 9%, incidence of the most common type, pancreatic ductal adenocarcinoma (PDAC), is growing and projected to be the second cause of cancer deaths by 2030.

8 Sep 2022

Promising anti-cancer agent may also prevent SARS-CoV-2 from replication

Based on findings from a new study by a Johns Hopkins Medicine-led research team, an effective means of fighting SARS-CoV-2, the virus that causes COVID-19, may be possible that circumvents the problem of waning immunity often observed when current vaccines deal with emerging COVID variants.

8 Sep 2022

Pitt researchers describe a pathway by which cells repair damaged lysosomes

Today in Nature, University of Pittsburgh researchers describe for the first time a pathway by which cells repair damaged lysosomes, structures that contribute to longevity by recycling cellular trash.

8 Sep 2022

Research identifies a promising path to developing therapies to treat esophageal tumors

Research led by Case Western Reserve University has identified a promising path to developing therapies to treat esophageal tumors––a form of cancer that not only is among the most deadly, but also has been occurring at increasing rates over the past decade.

8 Sep 2022

Insights into molecular structure of protein assembly that plays key role in controlling cristae architecture

Energy supply is a vital component of economic life. And the complex interplay between society and economy is jeopardized whenever core services or key industrial sectors are at risk of failing because of energy supply problems.

7 Sep 2022

Studies to explore whether achieving beneficial ketone levels can improve metabolic health of military service members

A series of upcoming studies will explore whether the grind of active-duty military life and veterans' disproportionately high incidence of chronic illness could be tamed by lifestyle interventions designed to achieve a metabolic state of nutritional ketosis.

7 Sep 2022

Discovery sheds light on an important aspect of gut health and mucosal immunity

Immune cells called group 3 innate lymphoid cells (ILC3s) play an essential role in establishing tolerance to symbiotic microbes that dwell in the human gastrointestinal tract, according to a study led by researchers at Weill Cornell Medicine.

7 Sep 2022

Clock gene-dependent glutamate signaling responsible for seasonal regulation of reproduction in bean bugs

Did you know that not only does organism's body have a biological clock that can tell the time of the day, it can also tell the time of the year? Now, researchers from Japan have found that one capable little molecule may be behind the mechanism by which the biological clock keeps track of the seasons.

6 Sep 2022

Discovery of bacteria-killing toxin could pave the way for new generation of antibiotics

Researchers at McMaster University have discovered a previously unknown bacteria-killing toxin that could pave the way for a new generation of antibiotics.

6 Sep 2022

Targeting Gαq/11 may be an efficient therapeutic strategy against uveal melanoma

Announcing a new article publication from Acta Pharmaceutica Sinica B. Constitutively activated G proteins caused by specific mutations mediate the development of multiple malignancies.

5 Sep 2022

Alternative approaches to functional and phenotypic assays using multi-parameter flow cytometry

Synexa is an industry-leading biomarker and large molecule bio analytic research service provider. In this interview, NewsMedical speaks with Natalie Strickland, a principal scientist at Synexa, about alternative approaches to flow cytometry.

From Synexa Life Sciences 5 Sep 2022

Research reveals a starring role for mitochondrial dynamics within adult muscle stem cells

Mitochondria are remarkable shape-shifting organelles that have long been understood as the powerhouses inside our cells.

2 Sep 2022

Inhibiting a key metabolic enzyme selectively kills melanoma cells and stops tumor growth

Researchers at Sanford Burnham Prebys, led by Ze'ev Ronai, Ph.D., have shown for the first time that inhibiting a key metabolic enzyme selectively kills melanoma cells and stops tumor growth.

1 Sep 2022

Intranasally delivered neutralizing antibody protects against SARS-CoV-2 Omicron and Delta variants

The current study focused on the ability of this nmAb to neutralize Delta, Omicron, and other VOCs, as well as its efficacy when given by the intranasal route in an animal model.

1 Sep 2022

dsDNA Quantification for NGS Quality Control

Andrew Jones discusses the importance of quality control in NGS and the effect that a poorly followed protocol can have on experimental results.

From DeNovix Inc. 1 Sep 2022

Improving 1 µL UV-Vis Spectrophotometry Sample Results

Prior to microvolume spectrophotometry, UV-Vis quantification of biomolecules was performed using quartz cuvettes with a 10mm pathlength.

From DeNovix Inc. 1 Sep 2022

Study reveals a vital route through which fascin promotes cancer development

The study reveals an important route through which fascin promotes cancer development and provides insights into potential pathways that could block its action.

30 Aug 2022

Molecule News and Research

Molecular probes can track the progress of protein that misbehaves in neurodegenerative diseases

Researchers produce high-resolution crystal structure of enzyme critical to SARS-CoV-2 survival

Researchers review role of melatonin in pregnancies complicated by placental insufficiency

Study provides a potential game-changer in assessing treatment response in pancreatic cancer patients

Promising anti-cancer agent may also prevent SARS-CoV-2 from replication

Pitt researchers describe a pathway by which cells repair damaged lysosomes

Research identifies a promising path to developing therapies to treat esophageal tumors

Insights into molecular structure of protein assembly that plays key role in controlling cristae architecture

Studies to explore whether achieving beneficial ketone levels can improve metabolic health of military service members

Discovery sheds light on an important aspect of gut health and mucosal immunity

Clock gene-dependent glutamate signaling responsible for seasonal regulation of reproduction in bean bugs

Discovery of bacteria-killing toxin could pave the way for new generation of antibiotics

Targeting Gαq/11 may be an efficient therapeutic strategy against uveal melanoma

Alternative approaches to functional and phenotypic assays using multi-parameter flow cytometry

Research reveals a starring role for mitochondrial dynamics within adult muscle stem cells

Inhibiting a key metabolic enzyme selectively kills melanoma cells and stops tumor growth

Intranasally delivered neutralizing antibody protects against SARS-CoV-2 Omicron and Delta variants

dsDNA Quantification for NGS Quality Control

Improving 1 µL UV-Vis Spectrophotometry Sample Results

Study reveals a vital route through which fascin promotes cancer development

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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