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Researchers explore how HIV spreads in 3D tissue-like environments

The spread of pathogens like the human immunodeficiency virus (HIV) is often studied in a test tube, i.e. in two-dimensional cell cultures, even though it hardly reflects the much more complex conditions in the human body.

25 Jul 2019

Study identifies new mechanism that impacts HIV infection

A team of scientists led by Texas Biomed's Assistant Professor Smita Kulkarni, Ph.D. and Mary Carrington, Ph.D., at the Frederick National Laboratory for Cancer Research, published results of a study that pinpointed a long noncoding RNA molecule which influences a key receptor involved in HIV infection and progression of the disease.

25 Jul 2019

New vaccine shows promise against toughest HIV strains

A new study reports successful immunization against a so-far invincible “death star” strain of an HIV-related laboratory virus (SIVmac239) and another tough strain. The new approach also achieves long-term protection with a single dose, showing that gene therapy could allow broad and durable protection, based on a modified form of the CD4 protein that allows HIV entry into human cells.

24 Jul 2019

Vaginal ring used by most women for HIV prevention in open-label study

In an open-label study of women in southern and eastern Africa, a vaginal ring that is inserted once a month and slowly releases an antiviral drug was estimated to reduce the risk of HIV by 39%, according to statistical modeling.

24 Jul 2019

New vaccine containing DNA and recombinant proteins may protect from HIV

Researchers at the Icahn School of Medicine at Mount Sinai have developed a novel vaccine consisting of DNA and recombinant proteins?proteins composed of a portion of an HIV protein and another unrelated protein.

24 Jul 2019

Tailored adherence strategies needed to engage young African women in consistent PrEP use

In a study of open-label Truvada as daily pre-exposure prophylaxis (PrEP) to prevent HIV among 427 young African women and adolescent girls, 95% initiated the HIV prevention strategy, and most used PrEP for the first three months.

24 Jul 2019

Folic acid supplementation mitigates risk of neural tube defects linked to HIV drug

Dolutegravir is a preferred medication for treating HIV infection, but it recently has been linked to a 6- to 9-fold increase in the risk for neural tube defects among babies born to mothers receiving the drug during early gestation.

24 Jul 2019

New analysis quantifies how stimulant treatment reduces serious outcomes of ADHD

An analysis of three previous studies of children and young adults with attention-deficit hyperactivity disorder quantifies for the first time the extent to which stimulant treatment reduces the development of mood disorders, school problems, conduct disorders, substance use disorders and other problems.

23 Jul 2019

Connection to HIV treatment services helps gay, bisexual population to achieve viral suppression

Gay, bisexual and other men who have sex with men and transgender women with HIV, who are not in care, can be engaged in care when reached and connected with HIV treatment services, according to findings from a clinical trial supported by the National Institutes of Health.

23 Jul 2019

Recreational drugs more likely to be tried for the first time in summer, study shows

American teenagers and adults are more likely to try illegal or recreational drugs for the first time in the summer, a new study shows.

23 Jul 2019

Continuation of community-wide HIV testing could lead to reductions in new HIV cases

Continuation of community-wide HIV testing and prompt initiation of treatment as delivered in the HPTN 071 study in South Africa and Zambia could lead to substantial reductions in new HIV cases, be cost-effective, and help to achieve the UNAIDS 2030 targets, according to projections from mathematical modeling and cost-effectiveness analyses presented today at the 10th International AIDS Society Conference on HIV Science in Mexico City.

23 Jul 2019

People successfully treated for visceral leishmaniasis can still infect others, study confirms

The results of an innovative "infectivity" study conducted by the Drugs for Neglected Diseases initiative and the International Centre for Diarrhoeal Disease Research, Bangladesh confirm that people successfully treated for visceral leishmaniasis in South Asia can still infect others if they develop a skin condition known as post-kala-azar dermal leishmaniasis.

22 Jul 2019

IAS 2019 spotlights challenge of providing HIV services in humanitarian crises

More than 5,000 people from 140 counties have gathered in Mexico City for the opening of the 10th IAS Conference on HIV Science, where global experts called for urgent action to address the health needs of millions of people affected by humanitarian crises.

22 Jul 2019

IAS 2019 conference provides in-depth insights on global HIV crisis

On Sunday 21 July, from 18:00 – 18:45 (CDT), leaders in the HIV field will brief journalists just before the start of the 10th IAS Conference on HIV Science opening session on the most current and pressing global health challenges, including the recent state of humanitarian conflict, natural disasters, global migration, and regional outbreaks.

22 Jul 2019

Scientists confirm HIV theory by sequencing 53-year old tissue

Researchers have extracted a near-complete HIV-1 genome from the lymph node tissue of a man who has been embedded in wax since 1966.

22 Jul 2019

Study uncovers gene that hides tumor cells from immunotherapy

A team at Fred Hutchinson Cancer Research Center has identified a gene that could make immunotherapy treatments, specifically checkpoint inhibitors, work for a wider variety of cancer patients.

19 Jul 2019

Opioid overdose deaths on the decline says CDC but the real picture may still be grim

The opioid epidemic began in the 1990s with hundreds of deaths occurring each year due to overdose of these drugs of abuse. According to the Centre for Disease Prevention and Control (CDC), for the first time in two decades, there has been a drop of 5 percent in the opioid overdose deaths in 2018.

17 Jul 2019

Study identifies genomic differences that impact response to Cryptococcus infection

Cryptococcus neoformans is a fungal pathogen that infects people with weakened immune systems, particularly those with advanced HIV/AIDS. New University of Minnesota Medical Research could mean a better understanding of this infection and potentially better treatments for patients.

16 Jul 2019

HIV therapy leaves unrepaired holes in the immune system's wall of defense

If they don't receive antiretroviral therapy (ART), most HIV patients see a progressive weakening of their immune system.

16 Jul 2019

HIV DNA persists in spinal fluid despite treatment, linked to cognitive impairment

Many people living with the human immunodeficiency virus (HIV) and using antiretroviral therapy (ART) may still have cells sheltering the virus lurking in the cerebrospinal fluid, a new study has found.

16 Jul 2019

HIV News and Research

Researchers explore how HIV spreads in 3D tissue-like environments

Study identifies new mechanism that impacts HIV infection

New vaccine shows promise against toughest HIV strains

Vaginal ring used by most women for HIV prevention in open-label study

New vaccine containing DNA and recombinant proteins may protect from HIV

Tailored adherence strategies needed to engage young African women in consistent PrEP use

Folic acid supplementation mitigates risk of neural tube defects linked to HIV drug

New analysis quantifies how stimulant treatment reduces serious outcomes of ADHD

Connection to HIV treatment services helps gay, bisexual population to achieve viral suppression

Recreational drugs more likely to be tried for the first time in summer, study shows

Continuation of community-wide HIV testing could lead to reductions in new HIV cases

People successfully treated for visceral leishmaniasis can still infect others, study confirms

IAS 2019 spotlights challenge of providing HIV services in humanitarian crises

IAS 2019 conference provides in-depth insights on global HIV crisis

Scientists confirm HIV theory by sequencing 53-year old tissue

Study uncovers gene that hides tumor cells from immunotherapy

Opioid overdose deaths on the decline says CDC but the real picture may still be grim

Study identifies genomic differences that impact response to Cryptococcus infection

HIV therapy leaves unrepaired holes in the immune system's wall of defense

HIV DNA persists in spinal fluid despite treatment, linked to cognitive impairment

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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