Biomarker News and Research

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A biomarker is a biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Also called molecular marker and signature molecule.

A 'sniff test' could signal consciousness after a brain injury

A team of scientists at the Weizmann Institute of Science in Israel revealed that the ability to detect smells predicts recovery and long-term survival in patients who had a severe brain injury. The study, published in the journal Nature, shows that the simple "sniff test," which is inexpensive and convenient, could help doctors to diagnose and develop treatments for patients who have brain injuries and unconsciousness.

3 May 2020

AHA awards grants to 12 teams for fast-tracked heart and brain health research related to COVID-19

Less than a month after issuing a rapid response call for scientific research proposals for fast-tracked studies of the effects of COVID-19 on the body's cardiovascular and cerebrovascular systems, the American Heart Association has awarded $1.2 million in grants to teams at 12 institutions across the U.S. to begin this unprecedented work.

2 May 2020

Using Multiplex Assays to Discover Biomarkers for Parkinson’s Disease

In this interview, Dr. Polinski and Dr. Atabakhsh discuss the importance of developing biomarkers for Parkinson’s and the partnership between MJFF and Abcam.

From Abcam 1 May 2020

Multicolor Immunohistochemistry (IHC): Going Beyond a Single Color

An interview with Dr. Will Howat at SfN 2018, discussing the possibilities and challenges of immunohistochemistry (IHC) beyond a single color!

From Abcam 1 May 2020

ACCC's BiomarkerLIVE project facilitates integration of precision medicine into practice

As the science and knowledge around biomarkers and molecular profiling continues to expand, oncology providers are challenged with efficiently implementing molecular testing into their everyday practice.

30 Apr 2020

Drug combo for untreated CLL approved by FDA based on E1912 trial

Patients with untreated chronic lymphocytic leukemia or small lymphocytic lymphoma now have a new treatment option--a combination of the targeted agent ibrutinib with the immunologic agent rituximab.

29 Apr 2020

Study reveals how APOE4 triggers leaks in the blood-brain barrier

New USC research reveals how APOE4, a genetic culprit for Alzheimer's disease, triggers leaks in the brain's plumbing system, allowing toxic substances to seep into the brain areas responsible for memory encoding and other cognitive functions.

29 Apr 2020

Kurome secures license to develop novel therapies for chemo-resistant cancer

Seed investor CincyTech announced the formation of Kurome Therapeutics ("Kurome"), a preclinical stage company developing novel therapies targeting cancer cells' adaptive resistance mechanisms beginning with hematopoietic, or blood cell, cancers.

29 Apr 2020

Gustave Roussy and Biognosys Announce Partnership

The severe pneumonitis in patients infected by SARS-Cov-2 requires prolonged treatment in intensive care units with mechanical ventilation.

From Biognosys 28 Apr 2020

Caprion - HistoGeneX Expands its biomarker capabilities and deploys molecular COVID-19 testing services

Caprion - HistoGeneX announced today that the company is launching a molecular PCR testing service for identifying patients with COVID-19.

28 Apr 2020

Duke engineers awarded NSF grant to adapt fast, low-cost diagnostic tool for COVID-19

Biomedical engineers at Duke University are adapting a rapid testing platform originally designed to detect Ebola to see whether it could be of use in detecting antigens to SARS-Cov-2, the virus that causes COVID-19.

27 Apr 2020

Gut microbiota could predict severity of COVID-19

The COVID-19 pandemic is spreading to every corner of the world. But not everyone is falling sick at the same rate. A new study published on the preprint server medRxiv in April 2020 suggests that the composition of the gut microbiome could partially explain the difference in susceptibility. This adds a new dimension to what is currently known about the disease.

27 Apr 2020

Decreasing early neuroinflammation could slow Alzheimer's progression

In a new animal study examining Alzheimer's disease, researchers found that disease progression could be slowed by decreasing neuroinflammation in the brain before memory problems and cognitive impairment were apparent.

27 Apr 2020

Simple blood test offers early warning of chemotherapy-related cardiac dysfunction

Scientists have identified a collection of biomarkers that together signal that a person's cancer treatment may be harming their heart.

27 Apr 2020

Mapping complex peripheral immune response to severe COVID-19

In a recent article publicly available at medRxiv, researchers from Stanford have presented a single-cell atlas of the peripheral immune response to coronavirus disease (COVID-19), highlighting pertinent immunological features associated with the severe forms of the disease.

26 Apr 2020

Australian researchers develop world’s first ultrasound biosensor

Australian researchers have made a world-first breakthrough that has the potential to monitor the changes in pH levels and other responses to therapy in stroke and cancer patients.

24 Apr 2020

New nanobiosensor can help diagnose early-stage multiple sclerosis

Researchers at the Federal University of São Carlos in Sorocaba have developed a technique to diagnose early-stage multiple sclerosis, a disease of the central nervous system, and distinguish it from neuromyelitis optica, a rare yet severe autoimmune inflammatory process also affecting the central nervous system.

23 Apr 2020

Higher levels of specific gene can indicate better prognosis in prostate cancer

The most common form of cancer in older men is prostate cancer. In many cases the tumor grows slowly and can be treated effectively, but it is sometimes more aggressive and becomes terminal.

23 Apr 2020

Researchers develop new blood test for Alzheimer's disease

A new blood test for Alzheimer's disease has been developed under the leadership of researchers at the University of Gothenburg, Sweden. The method is based on measuring a specific variant of tau protein in ordinary blood samples, which makes the test relatively simple and cheap to perform.

23 Apr 2020

UMB and UMD fund cross-campus research projects

The University of Maryland, Baltimore (UMB) and the University of Maryland, College Park (UMD) are funding new cross-campus research projects as part of a new joint program that seeks to solve big health care challenges through joint research that draws on the institutions world leading expertise in medicine and artificial intelligence.

23 Apr 2020